Sociodemographic and clinical characterization of cases of 1,103 non-syndromic and 66 syndromic odontogenic keratocyst: a Brazilian multicenter study.

التفاصيل البيبلوغرافية
العنوان:	Sociodemographic and clinical characterization of cases of 1,103 non-syndromic and 66 syndromic odontogenic keratocyst: a Brazilian multicenter study.
المؤلفون:	Pereira Santana DC; School of Dentistry, Postgraduation Program in Dentistry and Health, Federal University of Bahia, Salvador, Brazil., Abbehusen Couto L; School of Dentistry, Postgraduation Program in Dentistry and Health, Federal University of Bahia, Salvador, Brazil., de Santana Passos-Soares J; Department of Social and Pediatric Dentistry, School of Dentistry da Federal, Postgraduation Program in Dentistry and Health, University of Bahia, Salvador, Brazil., Caló de Aquino Xavier F; Surgical Pathology Service, School of Dentistry, Postgraduation Program in Dentistry and Health, Federal University of Bahia, Salvador, Brazil., Alves Mesquita R; Department of Dental Clinical Practice, Pathology and Surgery, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil., Aragão Felix F; Department of Dental Clinical Practice, Pathology and Surgery, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil., da Silva TA; Department of Dental Clinical Practice, Pathology and Surgery, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil., Weege Nonaka CF; Department of Dentistry, State University of Paraíba, Campina Grande, Brazil., Muniz Alves P; Department of Dentistry, State University of Paraíba, Campina Grande, Brazil., Rodrigues Ferreira C; Department of Dentistry, State University of Paraíba, Campina Grande, Brazil., Libório-Kimura TN; Department of Pathology and Forensic Medicine (DPML), Federal University of Amazonas, Manaus, Brazil., Castro de Oliveira Moreira L; Department of Pathology and Forensic Medicine (DPML), Federal University of Amazonas, Manaus, Brazil., Câmara J; Department of Pathology and Forensic Medicine (DPML), Federal University of Amazonas, Manaus, Brazil., Alfaia Silva C; Department of Pathology and Forensic Medicine (DPML), Federal University of Amazonas, Manaus, Brazil., de Mendonça EF; Laboratory of Oral Pathology, School of Dentistry, Federal University of Goiás, Goiânia, Brazil., do Lago Costa N; Laboratory of Oral Pathology, School of Dentistry, Federal University of Goiás, Goiânia, Brazil., Rebelo Pontes HA; Oral Pathology Service, João de Barros, Barreto University Hospital, Federal University of Pará, Belém, Brazil., Lacerda de Souza L; Oral Pathology Service, João de Barros, Barreto University Hospital, Federal University of Pará, Belém, Brazil., Freire de Castro Lisboa J; Department of Clinical and Preventive Dentistry, Federal University of Pernambuco, Recife, Brazil., Pina Godoy G; Department of Clinical and Preventive Dentistry, Federal University of Pernambuco, Recife, Brazil., Azevedo Lins de Holanda L; Department of Clinical and Preventive Dentistry, Federal University of Pernambuco, Recife, Brazil., Domingues Martins M; Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil., Varvaki Rados P; Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil., Schmidt TR; Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil., de Almeida Freitas R; Postgraduate Program in Dental Sciences, Federal University of Rio Grande Do Norte, Natal, Brazil., Batista de Souza L; Postgraduate Program in Dental Sciences, Federal University of Rio Grande Do Norte, Natal, Brazil., Freitas de Morais E; Postgraduate Program in Dental Sciences, Federal University of Rio Grande Do Norte, Natal, Brazil., Vargas PA; Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Piracicaba, Brazil., Ajudarte Lopes M; Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Piracicaba, Brazil., Alves Quixabeira Oliveira G; Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Piracicaba, Brazil., Nunes Dos Santos J; Surgical Pathology Service, School of Dentistry, Postgraduation Program in Dentistry and Health, Federal University of Bahia, Salvador, Brazil., Gomes Henriques ÁC; Surgical Pathology Service, School of Dentistry, Postgraduation Program in Dentistry and Health, Federal University of Bahia, Salvador, Brazil. aguidacgh@gmail.com.
المصدر:	Clinical oral investigations [Clin Oral Investig] 2023 Nov; Vol. 27 (11), pp. 6951-6959. Date of Electronic Publication: 2023 Oct 19.
نوع المنشور:	Multicenter Study; Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9707115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-3771 (Electronic) Linking ISSN: 14326981 NLM ISO Abbreviation: Clin Oral Investig
أسماء مطبوعة:	Publication: Berlin : Springer-Verlag Original Publication: Berlin : Springer, c1997-
مواضيع طبية MeSH:	Odontogenic Cysts/pathology , Odontogenic Tumors, Humans ; Retrospective Studies ; Brazil ; Cross-Sectional Studies
مستخلص:	Objectives: This multicenter study aimed to evaluate cases of non-syndrome and syndromic odontogenic keratocyst, as well as cases of recurrence within these two groups. Methods: This descriptive, analytical, retrospective cross-sectional study evaluated the sex, age and presence of multiple lesions in 1,169 individuals seen at 10 Brazilian oral and maxillofacial pathology centers. Of these, 1,341 odontogenic keratocysts were analyzed regarding clinical diagnosis, size, site, imaging appearance, signs and symptoms, type of biopsy, treatment, and recurrence. Results: There was a similar distribution by sex. The median age of non-syndromic and syndromic patients was 32 and 17.5 years, respectively. The posterior mandible was the site most affected by small and large lesions in both groups and in recurrent cases. Unilocular lesions were more frequent, also in recurrent cases. Mainly small lesions showed this imaging appearance. Signs and symptoms were absent in most cases. Conservative treatment was the most frequent modality in all age groups, regardless of the patient's condition and recurrence. Recurrences were uncommon. Conclusion: This study showed a higher frequency of non-syndromic keratocysts in the population. Clinicopathological features related to the involvement of multiple sites, age, and recurrence may differ between syndromic and non-syndromic cases. Furthermore, we found an association between lesion size and some clinical features and between the time interval to recurrence and the syndromic spectrum. Clinical Relevance: To contribute to a better understanding of the distribution and association between clinical, imaging, and sociodemographic characteristics in each spectrum of the lesion. (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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فهرسة مساهمة:	Keywords: Keratocyst; Multicenter Study; Odontogenic Cyst; Oral Pathology
تواريخ الأحداث:	Date Created: 20231019 Date Completed: 20231108 Latest Revision: 20240308
رمز التحديث:	20240308
DOI:	10.1007/s00784-023-05313-7
PMID:	37855921
قاعدة البيانات:	MEDLINE

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تدمد:	1436-3771
DOI:	10.1007/s00784-023-05313-7