دورية أكاديمية
Review of Analytical Methods for Evaluating Azithromycin in the Context of Green Analytical Chemistry.
| العنوان: | Review of Analytical Methods for Evaluating Azithromycin in the Context of Green Analytical Chemistry. |
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| المؤلفون: | Sinzervinch A; Department of Pharmacy, Faculty of Pharmacy, Federal University of Goiás, Goiânia, Brazil., Lustosa IA; Department of Pharmacy, Faculty of Pharmacy, Federal University of Goiás, Goiânia, Brazil., Kogawa AC; Department of Pharmacy, Faculty of Pharmacy, Federal University of Goiás, Goiânia, Brazil. |
| المصدر: | Current pharmaceutical design [Curr Pharm Des] 2023; Vol. 29 (30), pp. 2369-2376. |
| نوع المنشور: | Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9602487 Publication Model: Print Cited Medium: Internet ISSN: 1873-4286 (Electronic) Linking ISSN: 13816128 NLM ISO Abbreviation: Curr Pharm Des Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Saif Zone, Sharjah, U.A.E. : Bentham Science Publishers Original Publication: Schiphol, The Netherlands : Bentham Science Publishers, c1995- |
| مواضيع طبية MeSH: | Azithromycin* , Anti-Infective Agents*, Humans ; Methanol ; Agar ; Acetonitriles |
| مستخلص: | Background: Azithromycin (AZT) is an antimicrobial available in different pharmaceutical forms and many people can have access to this medicine. Therefore, the existence of adequate and reliable analytical methods for evaluating the quality of AZT and AZT-based products is essential. Objective/methods: The purpose of this review is to discuss the analytical methods for evaluating AZT present in the literature and official compendia in the context of Green Analytical Chemistry (GAC). Results: Among the methods found in the literature for evaluating AZT, the most used method is HPLC (62%) followed by TLC (14%) and the microbiological method by agar diffusion (14%). Even pharmacopoeias recommend the analysis of AZT by HPLC or agar diffusion. Acetonitrile and methanol account for 35% of the most used solvents in the analyses, followed by buffer. Conclusion: AZT lacks analytical methods in the context of GAC. Both physical-chemical and microbiological methods can contemplate the environmentally friendly way to analyze AZT and AZT-based products, depending only on the chosen conditions. Ethanol, purified water, acetic acid instead of methanol, acetonitrile, buffer, formic acid in the physical-chemical methods are excellent alternatives. However, in the microbiological method, turbidimetry is a great option instead of agar diffusion. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| فهرسة مساهمة: | Keywords: Azithromycin; analytical methods; antimicrobial.; environmentally friendly method; green analytical chemistry; quality control |
| المشرفين على المادة: | 83905-01-5 (Azithromycin) Y4S76JWI15 (Methanol) 9002-18-0 (Agar) 0 (Anti-Infective Agents) 0 (Acetonitriles) |
| تواريخ الأحداث: | Date Created: 20231020 Date Completed: 20231122 Latest Revision: 20240408 |
| رمز التحديث: | 20240409 |
| DOI: | 10.2174/0113816128271482231010053929 |
| PMID: | 37859323 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1873-4286 |
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| DOI: | 10.2174/0113816128271482231010053929 |