دورية أكاديمية
Laser speckle contrast imaging, an alternative to laser doppler imaging in clinical practice of burn wound care derivation of a color code.
| العنوان: | Laser speckle contrast imaging, an alternative to laser doppler imaging in clinical practice of burn wound care derivation of a color code. |
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| المؤلفون: | Dijkstra A; van Weel Bethesda Hospital, Department of Intensive Care, Dirksland, the Netherlands. Electronic address: DijkstraA@maasstadziekenhuis.nl., Guven G; Hacettepe University Faculty of Medicine, Department of Intensive Care, Ankara, Turkey., van Baar ME; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands., Trommel N; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands., Hofland HWC; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands., Kuijper TM; Maasstad Hospital, Department of Rheumatology, Rotterdam, the Netherlands., Ince C; Erasmus Medical Center, Department of Translational Intensive Care, Rotterdam, the Netherlands., Van der Vlies CH; Maasstad Hospital, Burn Centre, Rotterdam, the Netherlands. Electronic address: C.vandervlies@erasmusmc.nl. |
| المصدر: | Burns : journal of the International Society for Burn Injuries [Burns] 2023 Dec; Vol. 49 (8), pp. 1907-1915. Date of Electronic Publication: 2023 May 08. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8913178 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1409 (Electronic) Linking ISSN: 03054179 NLM ISO Abbreviation: Burns Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: [Guildford, Surrey, UK] : Butterworths, [c1989- |
| مواضيع طبية MeSH: | Burns*/diagnostic imaging , Burns*/therapy , Skin*/diagnostic imaging, Adult ; Humans ; Cohort Studies ; Laser Speckle Contrast Imaging ; Laser-Doppler Flowmetry/methods ; Lasers ; Prospective Studies |
| مستخلص: | Objective: To develop a color code and to investigate the validity of Laser Speckle Contrast Imaging (LSCI) for measuring burn wound healing potential (HP) in burn patients as compared to the reference standard Laser Doppler Imaging (LDI). Method: A prospective, observational, cohort study was conducted in adult patients with acute burn wounds. The relationship between mean flux measured with LDI and mean perfusion units (PU) measured with LSCI was expressed in a regression formula. Measurements were performed between 2 and 5 days after the burn wound. The creation of a LSCI color code was done by mapping the clinically validated color code of the LDI to the corresponding values on the LSCI scale. To assess validity of the LSCI, the ability of the LSCI to discriminate between HP < 14 and ≥ 14 days and HP < 21 and original ≥ 21 days according to the LDI reference standard was evaluated, with calculation of receiver operating characteristics (ROC) curves. Results: A total of 50 patients were included with a median age of 40 years and total body surface area burned of 6%. LSCI values of 143 PU and 113 PU were derived as the cut-off values for the need of conservative treatment (HP < 14 and ≥ 14 days) resp. surgical closure (HP < 21 and ≥ 21 days). These LSCI cut off values showed a good discrimination between HP 14 days versus ≥ 14 days (Area Under Curve (AUC)= 0.89; sensitivity 85% and specificity = 82%) and a good discrimination between HP 21 days versus ≥ 21 days (AUC of 0.89, sensitivity 81% and specificity 88%). Conclusion: This is the first study in which a color code for the LSCI in adult clinical burn patients has been developed. Our study reconfirms the good performance of the LSCI for prediction of burn wound healing potential. This provides additional evidence for the potential value of the LSCI in specialized burn care. Competing Interests: Declaration of Competing Interest The authors declare that they have no conflict of interest. Perimed AB provided the Laser Speckle Contrast Imager for free. Perimed AB did not have any involvement in the study design, data collection and data analysis, nor in the writing process and submission of this paper. (Copyright © 2023. Published by Elsevier Ltd.) |
| فهرسة مساهمة: | Keywords: Burns; Clinical practice; Color code; Laser doppler imaging; Laser speckle contrast imaging; Validation |
| تواريخ الأحداث: | Date Created: 20231020 Date Completed: 20231214 Latest Revision: 20240712 |
| رمز التحديث: | 20240713 |
| DOI: | 10.1016/j.burns.2023.04.009 |
| PMID: | 37863755 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1879-1409 |
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| DOI: | 10.1016/j.burns.2023.04.009 |