دورية أكاديمية
Systematic review: predictive value of organoids in colorectal cancer.
| العنوان: | Systematic review: predictive value of organoids in colorectal cancer. |
|---|---|
| المؤلفون: | Sakshaug BC; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Folkesson E; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Haukaas TH; Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway., Visnes T; Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway., Flobak Å; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway. asmund.flobak@ntnu.no.; Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway. asmund.flobak@ntnu.no.; The Cancer Clinic, St Olav's University Hospital, Prinsesse Kristinas Gate 1, 7030, Trondheim, Norway. asmund.flobak@ntnu.no. |
| المصدر: | Scientific reports [Sci Rep] 2023 Oct 23; Vol. 13 (1), pp. 18124. Date of Electronic Publication: 2023 Oct 23. |
| نوع المنشور: | Systematic Review; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
| مواضيع طبية MeSH: | Colorectal Neoplasms*/therapy, Humans ; Organoids |
| مستخلص: | While chemotherapy alone or in combination with radiotherapy and surgery are important modalities in the treatment of colorectal cancer, their widespread use is not paired with an abundance of diagnostic tools to match individual patients with the most effective standard-of-care chemo- or radiotherapy regimens. Patient-derived organoids are tumour-derived structures that have been shown to retain certain aspects of the tissue of origin. We present here a systematic review of studies that have tested the performance of patient derived organoids to predict the effect of anti-cancer therapies in colorectal cancer, for chemotherapies, targeted drugs, and radiation therapy, and we found overall a positive predictive value of 68% and a negative predictive value of 78% for organoid informed treatment, which outperforms response rates observed with empirically guided treatment selection. (© 2023. Springer Nature Limited.) |
| References: | Cell Stem Cell. 2022 Jun 2;29(6):905-917.e6. (PMID: 35508177) BMJ. 2021 Mar 29;372:n71. (PMID: 33782057) iScience. 2023 Jun 13;26(7):107116. (PMID: 37426352) Front Oncol. 2022 Feb 09;11:756214. (PMID: 35223449) Sci Rep. 2016 Jan 11;6:19103. (PMID: 26752500) Clin Cancer Res. 2019 Sep 1;25(17):5376-5387. (PMID: 31175091) Int J Cancer. 2023 Feb 1;152(3):524-535. (PMID: 36161653) Lancet. 2018 Mar 17;391(10125):1023-1075. (PMID: 29395269) Cell. 2018 Jan 11;172(1-2):373-386.e10. (PMID: 29224780) Cancer Res. 2022 Jun 15;82(12):2298-2312. (PMID: 35472075) Nat Med. 2019 Oct;25(10):1607-1614. (PMID: 31591597) Cancer Med. 2020 Jan;9(1):361-373. (PMID: 31693304) Eur J Cancer. 2009 Jan;45(2):228-47. (PMID: 19097774) Int J Cancer. 2020 Sep 1;147(5):1405-1418. (PMID: 31989583) J Biomed Opt. 2007 Mar-Apr;12(2):024014. (PMID: 17477729) J Radiat Res. 2013 Nov 1;54(6):1161-3. (PMID: 23732771) J Clin Oncol. 2004 Apr 1;22(7):1209-14. (PMID: 15051767) Cancer Sci. 2019 Jan;110(1):345-355. (PMID: 30343529) Cancer Res. 2014 Sep 15;74(18):5184-94. (PMID: 25100563) Nat Methods. 2016 Jun;13(6):521-7. (PMID: 27135972) ESMO Open. 2023 Jun;8(3):101198. (PMID: 37119788) Clin Cancer Res. 2020 Jul 15;26(14):3662-3670. (PMID: 32376656) Crit Rev Oncol Hematol. 2021 Jan;157:103190. (PMID: 33310278) ESMO Open. 2021 Jun;6(3):100103. (PMID: 33887686) Cell Stem Cell. 2020 Jan 2;26(1):17-26.e6. (PMID: 31761724) N Engl J Med. 2019 Oct 24;381(17):1632-1643. (PMID: 31566309) Adv Sci (Weinh). 2022 Nov;9(31):e2204097. (PMID: 36058001) Sci Transl Med. 2019 Oct 9;11(513):. (PMID: 31597751) J Clin Invest. 2009 Jun;119(6):1429-37. (PMID: 19487819) Cell. 2015 May 7;161(4):933-45. (PMID: 25957691) Dis Colon Rectum. 2021 Jul 1;64(7):833-850. (PMID: 33709991) Biomedicines. 2023 Mar 30;11(4):. (PMID: 37189676) NPJ Precis Oncol. 2021 Apr 12;5(1):30. (PMID: 33846504) Mol Oncol. 2022 Jun;16(12):2396-2412. (PMID: 34850547) Nat Rev Mol Cell Biol. 2007 Oct;8(10):839-45. (PMID: 17684528) Dis Colon Rectum. 2023 May 1;66(5):733-743. (PMID: 36898057) Ann Oncol. 2008 Mar;19(3):508-15. (PMID: 17998284) Front Oncol. 2021 Mar 18;11:641980. (PMID: 33816288) CA Cancer J Clin. 2017 Mar;67(2):93-99. (PMID: 28094848) Cancers (Basel). 2021 Jul 27;13(15):. (PMID: 34359661) Science. 2018 Feb 23;359(6378):920-926. (PMID: 29472484) Clin Transl Med. 2021 Jan;11(1):e285. (PMID: 33463056) |
| تواريخ الأحداث: | Date Created: 20231023 Date Completed: 20231027 Latest Revision: 20231123 |
| رمز التحديث: | 20231123 |
| مُعرف محوري في PubMed: | PMC10593775 |
| DOI: | 10.1038/s41598-023-45297-8 |
| PMID: | 37872318 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 2045-2322 |
|---|---|
| DOI: | 10.1038/s41598-023-45297-8 |