دورية أكاديمية
Unlocking the secrets of doxepin hydrochloride's crystal structure: Insights from high-quality powder diffraction analysis.
| العنوان: | Unlocking the secrets of doxepin hydrochloride's crystal structure: Insights from high-quality powder diffraction analysis. |
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| المؤلفون: | Dezena RMB; Preformulation Specialist Consultant, Pharmaceutical Industry, Campinas, São Paulo, Brazil; Faculty of Pharmaceutical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil. Electronic address: renan_marcel@hotmail.com., Rosa PCP; Faculty of Pharmaceutical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil. |
| المصدر: | Annales pharmaceutiques francaises [Ann Pharm Fr] 2024 Mar; Vol. 82 (2), pp. 369-372. Date of Electronic Publication: 2023 Oct 25. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Masson Editeur Country of Publication: France NLM ID: 2985176R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0003-4509 (Print) Linking ISSN: 00034509 NLM ISO Abbreviation: Ann Pharm Fr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Paris : Elsevier Masson Editeur Original Publication: Paris : Masson et Cie |
| مواضيع طبية MeSH: | Doxepin*, Powder Diffraction ; Pharmaceutical Preparations |
| مستخلص: | Doxepin hydrochloride, a versatile pharmaceutical compound, has been the subject of extensive research aimed at elucidating its crystal structure and solid-state characteristics. In this manuscript, we explore the significance of high-quality powder diffraction data in unveiling the intricate details of doxepin hydrochloride's crystal lattice. By examining the refined atom coordinates, density functional theory (DFT) optimization, and intermolecular interactions, we gain valuable insights into its structural conformation. This knowledge highlights the importance of precise crystallographic data in advancing our understanding of complex compounds and their pharmaceutical applications. (Copyright © 2023 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Chlorhydrate de doxépine; Crystal structures; Density Functional Theory (DFT); Données de diffraction de poudre de haute qualité; Doxepin hydrochloride; Géométrie chimique quantique; High-quality powder diffraction data; Pharmaceutical science; Quantum chemical geometry; Science pharmaceutique; Structures cristallines; Théorie fonctionnelle de la densité (DFT) |
| المشرفين على المادة: | 1668-19-5 (Doxepin) 0 (Pharmaceutical Preparations) |
| تواريخ الأحداث: | Date Created: 20231026 Date Completed: 20240226 Latest Revision: 20240226 |
| رمز التحديث: | 20240226 |
| DOI: | 10.1016/j.pharma.2023.10.007 |
| PMID: | 37884079 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0003-4509 |
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| DOI: | 10.1016/j.pharma.2023.10.007 |