دورية أكاديمية
أعرض في EDS

Meaning-centered pain coping skills training for patients with metastatic cancer: Protocol for a randomized controlled efficacy trial.

التفاصيل البيبلوغرافية
العنوان: Meaning-centered pain coping skills training for patients with metastatic cancer: Protocol for a randomized controlled efficacy trial.
المؤلفون: Fisher HM; Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Duke Cancer Institute, Duke University Health System, Durham, NC, USA., Check DK; Duke Cancer Institute, Duke University Health System, Durham, NC, USA; Department of Population Health Sciences, Duke University Medical Center, Durham, NC, USA., Somers TJ; Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Duke Cancer Institute, Duke University Health System, Durham, NC, USA., Kelleher SA; Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Duke Cancer Institute, Duke University Health System, Durham, NC, USA., Majestic C; Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Duke Cancer Institute, Duke University Health System, Durham, NC, USA., Yu JA; Division of Pediatric Palliative and Supportive Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Reed SD; Department of Population Health Sciences, Duke University Medical Center, Durham, NC, USA; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, United States of America., Li Y; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, United States of America., Olsen MK; Department of Biostatistics & Bioinformatics, Duke University School of Medicine, Durham, NC, USA; Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA Health Care System, Durham, NC, USA., Lerebours R; Department of Biostatistics & Bioinformatics, Duke University School of Medicine, Durham, NC, USA., Keefe FJ; Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Duke Cancer Institute, Duke University Health System, Durham, NC, USA., Steinhauser KE; Duke Cancer Institute, Duke University Health System, Durham, NC, USA; Department of Population Health Sciences, Duke University Medical Center, Durham, NC, USA; Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA Health Care System, Durham, NC, USA; Center for the Study of Human Aging and Development, Duke University, Durham, NC, USA; Department of Medicine, Duke University Medical Center, Durham, NC, 27705, USA., Breitbart WS; Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Winger JG; Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Duke Cancer Institute, Duke University Health System, Durham, NC, USA. Electronic address: joseph.winger@duke.edu.
المصدر: Contemporary clinical trials [Contemp Clin Trials] 2023 Dec; Vol. 135, pp. 107363. Date of Electronic Publication: 2023 Oct 24.
نوع المنشور: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101242342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2030 (Electronic) Linking ISSN: 15517144 NLM ISO Abbreviation: Contemp Clin Trials Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, N.Y. : Elsevier, c2005-
مواضيع طبية MeSH: Quality of Life* , Neoplasms*/complications , Neoplasms*/therapy , Neoplasms*/pathology, Humans ; Pain ; Anxiety/etiology ; Anxiety/therapy ; Adaptation, Psychological ; Randomized Controlled Trials as Topic
مستخلص: Background: Many patients with advanced cancer describe pain as a debilitating symptom that greatly interferes with daily activities and enjoyment of life. Psychosocial interventions can improve cancer-related pain but rarely address spiritual concerns (e.g., loss of meaning, peace), which can influence the pain experience for those facing life-threatening illness. To address these needs, we systematically developed and pilot tested a novel psychosocial intervention called Meaning-Centered Pain Coping Skills Training (MCPC). In this randomized controlled trial, we aim to determine MCPC's efficacy for reducing pain interference (primary outcome) and improving secondary outcomes. We will also estimate MCPC's cost-effectiveness.
Method/design: Patients (target N = 210) with advanced solid tumor malignancies (Stage IV) and clinically-elevated pain interference will be enrolled and block randomized with equal allocation to MCPC + enhanced usual care or enhanced usual care alone. MCPC's four, videoconferenced, 45-60 min weekly sessions will be individually delivered by trained study therapists. Primary (pain interference) and secondary (pain severity, anxiety and depressive symptoms, pain self-efficacy, social support, spiritual well-being) patient-reported outcomes will be assessed at baseline, and 8-weeks (primary endpoint) and 12-weeks after baseline.
Conclusion: Our MCPC intervention is the first to systematically address the biopsychosocial-spiritual aspects of pain in patients with advanced cancer. If MCPC demonstrates efficacy, next steps will involve hybrid efficacy-effectiveness and implementation work to broaden access to this brief, manualized, remotely-delivered intervention, with the goal of reducing suffering in patients with life-threatening illness.
Competing Interests: Declaration of Competing Interest The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
References: J Pain Symptom Manage. 2016 Jun;51(6):1070-1090.e9. (PMID: 27112310)
Arch Psychiatr Nurs. 2007 Jun;21(3):150-61. (PMID: 17556108)
Pain Med. 2015 Jan;16(1):51-60. (PMID: 25159525)
Health Educ Behav. 2004 Apr;31(2):143-64. (PMID: 15090118)
Medicine (Baltimore). 2016 Mar;95(10):e2759. (PMID: 26962773)
Curr Oncol Rep. 2020 Jan 21;22(1):3. (PMID: 31965361)
Pain. 2014 Sep;155(9):1743-1754. (PMID: 24865795)
Arch Intern Med. 2005 Jul 25;165(14):1574-80. (PMID: 16043674)
Sleep Med. 2012 Feb;13(2):123-32. (PMID: 22172964)
Med Care. 2018 Jun;56(6):529-536. (PMID: 29668646)
Pain. 2017 Jun;158(6):1108-1112. (PMID: 28267060)
Am J Clin Oncol. 1982 Dec;5(6):649-55. (PMID: 7165009)
J Pain Symptom Manage. 2005 May;29(5):446-57. (PMID: 15904747)
Ann Behav Med. 2002 Winter;24(1):49-58. (PMID: 12008794)
Phys Ther. 2014 Oct;94(10):1443-54. (PMID: 24903113)
Gerontologist. 2002 Oct;42 Spec No 3:24-33. (PMID: 12415130)
J Behav Med. 2006 Feb;29(1):17-27. (PMID: 16400532)
JAMA. 2022 Jul 12;328(2):184-197. (PMID: 35819420)
PLoS One. 2016 Dec 22;11(12):e0168512. (PMID: 28005986)
J Behav Med. 2013 Oct;36(5):441-53. (PMID: 22752250)
Qual Life Res. 2020 Aug;29(8):2299-2310. (PMID: 32306302)
Cancer Nurs. 2006 Sep-Oct;29(5):400-5. (PMID: 17006114)
Pain. 2005 Jan;113(1-2):9-19. (PMID: 15621359)
Pain. 2010 Jul;150(1):173-182. (PMID: 20554116)
Med Care Res Rev. 2006 Apr;63(2):217-35. (PMID: 16595412)
Psychooncology. 2023 Jul;32(7):1096-1105. (PMID: 37173865)
Cancer Med. 2020 May;9(9):3202-3210. (PMID: 32129946)
Palliat Support Care. 2020 Jun;18(3):263-270. (PMID: 32115006)
Psychooncology. 2016 Dec;25(12):1380-1392. (PMID: 26810383)
Psychooncology. 2010 Jan;19(1):21-8. (PMID: 19274623)
Pain. 1995 Oct;63(1):77-83. (PMID: 8577493)
J Palliat Med. 2022 Jan;25(1):60-69. (PMID: 34388037)
J Gen Intern Med. 2018 Aug;33(8):1245-1252. (PMID: 29623512)
Pain Physician. 2013 Jul-Aug;16(4):379-89. (PMID: 23877454)
Support Care Cancer. 2020 Aug;28(8):3781-3789. (PMID: 31832824)
Ann Acad Med Singap. 1994 Mar;23(2):129-38. (PMID: 8080219)
J Clin Oncol. 2022 Jan 1;40(1):24-31. (PMID: 34292791)
Int J Psychiatry Med. 2016 Aug;51(6):563-575. (PMID: 28629291)
J Clin Epidemiol. 2011 May;64(5):507-16. (PMID: 21447427)
Soc Sci Med. 2009 Feb;68(3):562-9. (PMID: 19059687)
J Clin Oncol. 2012 Feb 10;30(5):539-47. (PMID: 22253460)
J Psychosoc Oncol. 2019 May-Jun;37(3):335-349. (PMID: 30585762)
Clin Psychol Sci. 2014 Jan 1;2(1):22-34. (PMID: 25821658)
Psychooncology. 2010 Mar;19(3):264-72. (PMID: 19367561)
J Biomed Inform. 2019 Jul;95:103208. (PMID: 31078660)
J Pain. 2023 Sep;24(9):1712-1720. (PMID: 37187219)
Cancer. 2018 Aug 1;124(15):3231-3239. (PMID: 29757459)
Psychooncology. 2019 Aug;28(8):1671-1678. (PMID: 31162756)
Assessment. 2011 Sep;18(3):263-83. (PMID: 21697139)
Support Care Cancer. 2021 Dec;29(12):7703-7714. (PMID: 34146165)
J Natl Compr Canc Netw. 2019 Aug 1;17(8):977-1007. (PMID: 31390582)
Med Care. 2002 Sep;40(9):771-81. (PMID: 12218768)
Clin Orthop Relat Res. 2017 Feb;475(2):498-507. (PMID: 27752988)
J Pain Symptom Manage. 2003 Jan;25(1):9-18. (PMID: 12565184)
J Pain Symptom Manage. 2022 Jun;63(6):e749-e755. (PMID: 35235856)
Cancer. 2019 Jul 15;125(14):2383-2393. (PMID: 31034600)
J Clin Epidemiol. 2012 Oct;65(10):1107-16. (PMID: 22818947)
Ann Intern Med. 2010 Jun 1;152(11):726-32. (PMID: 20335313)
J Pain Symptom Manage. 2007 Jun;33(6):661-75. (PMID: 17531909)
Psychooncology. 2018 Nov;27(11):2531-2545. (PMID: 29958339)
J Clin Oncol. 2015 Mar 1;33(7):749-54. (PMID: 25646186)
N Engl J Med. 1998 Apr 23;338(17):1193-201. (PMID: 9554861)
Cancer Pract. 2002 May-Jun;10 Suppl 1:S58-65. (PMID: 12027971)
Circ Cardiovasc Qual Outcomes. 2012 Jan;5(1):113-9. (PMID: 22147884)
معلومات مُعتمدة: P30 CA008748 United States CA NCI NIH HHS; P30 CA014236 United States CA NCI NIH HHS; R25 CA190169 United States CA NCI NIH HHS
فهرسة مساهمة: Keywords: Meaning-centered psychotherapy; Pain coping skills training; Pain management; Palliative care; Spirituality; cancer
تواريخ الأحداث: Date Created: 20231026 Date Completed: 20231128 Latest Revision: 20240521
رمز التحديث: 20240522
مُعرف محوري في PubMed: PMC10842087
DOI: 10.1016/j.cct.2023.107363
PMID: 37884120
قاعدة البيانات: MEDLINE
الوصف
تدمد:1559-2030
DOI:10.1016/j.cct.2023.107363