دورية أكاديمية
أعرض في EDS

Electron count and ligand composition influence the optical and chiroptical signatures of far-red and NIR-emissive DNA-stabilized silver nanoclusters.

التفاصيل البيبلوغرافية
العنوان: Electron count and ligand composition influence the optical and chiroptical signatures of far-red and NIR-emissive DNA-stabilized silver nanoclusters.
المؤلفون: Guha R; Department of Materials Science and Engineering, University of California Irvine CA 92697 USA stacy.copp@uci.edu., Gonzàlez-Rosell A; Department of Materials Science and Engineering, University of California Irvine CA 92697 USA stacy.copp@uci.edu., Rafik M; Department of Materials Science and Engineering, University of California Irvine CA 92697 USA stacy.copp@uci.edu., Arevalos N; Department of Materials Science and Engineering, University of California Irvine CA 92697 USA stacy.copp@uci.edu., Katz BB; Department of Chemistry, University of California Irvine CA 92697 USA., Copp SM; Department of Materials Science and Engineering, University of California Irvine CA 92697 USA stacy.copp@uci.edu.; Department of Physics and Astronomy, University of California Irvine CA 92697 USA.; Department of Chemical and Biomolecular Engineering, University of California Irvine CA 92697 USA.
المصدر: Chemical science [Chem Sci] 2023 Sep 11; Vol. 14 (41), pp. 11340-11350. Date of Electronic Publication: 2023 Sep 11 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Cambridge, UK : Royal Society of Chemistry, [2010]-
مستخلص: Near-infrared (NIR) emissive DNA-stabilized silver nanoclusters (Ag N -DNAs) are promising fluorophores in the biological tissue transparency windows. Hundreds of NIR-emissive Ag N -DNAs have recently been discovered, but their structure-property relationships remain poorly understood. Here, we investigate 19 different far-red and NIR emissive Ag N -DNA species stabilized by 10-base DNA templates, including well-studied emitters whose compositions and chiroptical properties have never been reported before. The molecular formula of each purified species is determined by high-resolution mass spectrometry and correlated to its optical absorbance, emission, and circular dichroism (CD) spectra. We find that there are four distinct compositions for Ag N -DNAs emissive at the far red/NIR spectral border. These emitters are either 8-electron clusters stabilized by two DNA oligomer copies or 6-electron clusters with one of three different ligand compositions: two oligomer copies, three oligomer copies, or two oligomer copies with additional chlorido ligands. Distinct optical and chiroptical signatures of 6-electron Ag N -DNAs correlate with each ligand composition. Ag N -DNAs with three oligomer ligands exhibit shorter Stokes shifts than Ag N -DNAs with two oligomers, and Ag N -DNAs with chlorido ligands have increased Stokes shifts and significantly suppressed visible CD transitions. Nanocluster electron count also significantly influences electronic structure and optical properties, with 6-electron and 8-electron Ag N -DNAs exhibiting distinct absorbance and CD spectral features. This study shows that the optical and chiroptical properties of NIR-emissive Ag N -DNAs are highly sensitive to nanocluster composition and illustrates the diversity of structure-property relationships for NIR-emissive Ag N -DNAs, which could be harnessed to precisely tune these emitters for bioimaging applications.
Competing Interests: There are no conflicts to declare.
(This journal is © The Royal Society of Chemistry.)
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تواريخ الأحداث: Date Created: 20231027 Latest Revision: 20231028
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10599602
DOI: 10.1039/d3sc02931j
PMID: 37886084
قاعدة البيانات: MEDLINE
الوصف
تدمد:2041-6520
DOI:10.1039/d3sc02931j