دورية أكاديمية
أعرض في EDS

Role of the Circadian Gas-Responsive Hemeprotein NPAS2 in Physiology and Pathology.

التفاصيل البيبلوغرافية
العنوان: Role of the Circadian Gas-Responsive Hemeprotein NPAS2 in Physiology and Pathology.
المؤلفون: Murgo E; Department of Medical Sciences, Division of Internal Medicine and Chronobiology Laboratory, Fondazione IRCCS 'Casa Sollievo della Sofferenza', 71013 San Giovanni Rotondo, Italy., Colangelo T; Department of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71100 Foggia, Italy.; Cancer Cell Signaling Unit, Fondazione IRCCS 'Casa Sollievo della Sofferenza', 71013 San Giovanni Rotondo, Italy., Bellet MM; Department of Medicine and Surgery, University of Perugia, P.le L. Severi 1, 06132 Perugia, Italy., Malatesta F; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy., Mazzoccoli G; Department of Medical Sciences, Division of Internal Medicine and Chronobiology Laboratory, Fondazione IRCCS 'Casa Sollievo della Sofferenza', 71013 San Giovanni Rotondo, Italy.
المصدر: Biology [Biology (Basel)] 2023 Oct 22; Vol. 12 (10). Date of Electronic Publication: 2023 Oct 22.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101587988 Publication Model: Electronic Cited Medium: Print ISSN: 2079-7737 (Print) Linking ISSN: 20797737 NLM ISO Abbreviation: Biology (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, 2012-
مستخلص: Neuronal PAS domain protein 2 (NPAS2) is a hemeprotein comprising a basic helix-loop-helix domain (bHLH) and two heme-binding sites, the PAS-A and PAS-B domains. This protein acts as a pyridine nucleotide-dependent and gas-responsive CO-dependent transcription factor and is encoded by a gene whose expression fluctuates with circadian rhythmicity. NPAS2 is a core cog of the molecular clockwork and plays a regulatory role on metabolic pathways, is important for the function of the central nervous system in mammals, and is involved in carcinogenesis as well as in normal biological functions and processes, such as cardiovascular function and wound healing. We reviewed the scientific literature addressing the various facets of NPAS2 and framing this gene/protein in several and very different research and clinical fields.
References: Front Med (Lausanne). 2023 Feb 01;9:1014763. (PMID: 36816724)
Neuropsychopharmacology. 2010 May;35(6):1279-89. (PMID: 20072116)
Cell Signal. 2022 Jul;95:110332. (PMID: 35430345)
Nat Struct Mol Biol. 2013 Oct;20(10):1206-13. (PMID: 24056944)
Int J Cancer. 2012 Dec 1;131(11):2547-52. (PMID: 22473669)
J Neurosci. 2019 Jun 12;39(24):4657-4667. (PMID: 30962277)
Semin Cell Dev Biol. 2022 Jun;126:87-96. (PMID: 33810978)
J Biol Chem. 2010 Nov 12;285(46):35386-92. (PMID: 20817722)
Biochem Pharmacol. 2022 Dec;206:115345. (PMID: 36379250)
Front Immunol. 2022 Jan 27;13:777724. (PMID: 35154101)
PLoS One. 2018 Jun 29;13(6):e0199622. (PMID: 29958276)
Science. 2010 Dec 3;330(6009):1349-54. (PMID: 21127246)
Cell. 2008 Jul 25;134(2):329-40. (PMID: 18662547)
Front Mol Neurosci. 2017 Nov 03;10:360. (PMID: 29163035)
Cell. 2008 Jul 25;134(2):317-28. (PMID: 18662546)
J Biol Rhythms. 2005 Oct;20(5):404-18. (PMID: 16267380)
Physiol Res. 2017 Dec 30;66(Suppl 4):S501-S510. (PMID: 29355377)
J Transl Med. 2018 Dec 5;16(1):338. (PMID: 30518396)
Nat Rev Neurosci. 2018 Aug;19(8):453-469. (PMID: 29934559)
Ginekol Pol. 2023;94(1):33-40. (PMID: 36748323)
Science. 2000 Jun 23;288(5474):2226-30. (PMID: 10864874)
Neuron. 2017 Mar 22;93(6):1420-1435.e5. (PMID: 28285822)
J Appl Physiol (1985). 2009 Dec;107(6):1972-80. (PMID: 19696364)
J Clin Invest. 2013 Dec;123(12):5389-400. (PMID: 24270424)
Science. 2001 Jul 20;293(5529):510-4. (PMID: 11441146)
Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1036-47. (PMID: 18156197)
Chronobiol Int. 2015;32(6):785-91. (PMID: 26134245)
Annu Rev Neurosci. 2023 Jul 10;46:123-143. (PMID: 36854316)
FEBS Lett. 2014 Aug 1;588(15):2477-83. (PMID: 24911207)
Breast Cancer Res Treat. 2010 Apr;120(3):663-9. (PMID: 19649706)
BMC Med. 2018 Feb 19;16(1):20. (PMID: 29455641)
eNeuro. 2018 Oct 2;5(5):. (PMID: 30283813)
FEBS J. 2006 Jun;273(11):2528-39. (PMID: 16704425)
J Cancer. 2022 Sep 1;13(11):3199-3208. (PMID: 36118525)
Ann Med. 2007;39(3):229-38. (PMID: 17457720)
Biol Psychiatry. 2015 Mar 1;77(5):425-433. (PMID: 25444159)
Int J Mol Sci. 2020 Apr 27;21(9):. (PMID: 32349365)
World J Gastroenterol. 2023 Jun 21;29(23):3645-3657. (PMID: 37398880)
Exp Biol Med (Maywood). 2017 Sep;242(15):1553-1558. (PMID: 28799406)
Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):713-8. (PMID: 9012850)
PeerJ. 2023 Jan 20;11:e14734. (PMID: 36699999)
Nat Neurosci. 2007 May;10(5):543-5. (PMID: 17417633)
Heliyon. 2022 Aug 11;8(8):e10164. (PMID: 36016532)
Nucleic Acids Res. 2011 Jun;39(11):4769-82. (PMID: 21317191)
Nat Rev Genet. 2005 Jul;6(7):544-56. (PMID: 15951747)
Cell Death Dis. 2017 Mar 23;8(3):e2704. (PMID: 28333141)
Genome Biol. 2021 Apr 15;22(1):105. (PMID: 33858483)
Genes Dev. 2001 Apr 15;15(8):995-1006. (PMID: 11316793)
Science. 2001 Jul 20;293(5529):506-9. (PMID: 11441147)
Mol Cell Biol. 2008 Oct;28(19):6056-65. (PMID: 18644859)
Front Oncol. 2022 Oct 17;12:1031728. (PMID: 36324565)
Nat Commun. 2020 Jul 7;11(1):3394. (PMID: 32636383)
Sleep Med Clin. 2015 Dec;10(4):403-12. (PMID: 26568118)
Acta Physiol (Oxf). 2021 Mar;231(3):e13548. (PMID: 32846050)
Science. 2002 Dec 20;298(5602):2385-7. (PMID: 12446832)
FEBS Lett. 2013 Jul 11;587(14):2131-6. (PMID: 23735699)
Biochem Biophys Res Commun. 2014 Jul 25;450(2):1058-62. (PMID: 24978311)
Eur J Neurosci. 2022 Feb;55(3):675-693. (PMID: 35001440)
J Neural Transm (Vienna). 2012 Oct;119(10):1133-45. (PMID: 22538398)
Bioessays. 2016 Apr;38(4):394-405. (PMID: 26866932)
Sci Rep. 2018 Aug 10;8(1):11996. (PMID: 30097595)
Nat Rev Neurosci. 2003 Aug;4(8):649-61. (PMID: 12894240)
Int J Clin Exp Med. 2015 May 15;8(5):7176-83. (PMID: 26221256)
Elife. 2022 Jan 18;11:. (PMID: 35040776)
Cancer Cell Int. 2019 Apr 05;19:87. (PMID: 30996687)
Int J Oncol. 2022 Dec;61(6):. (PMID: 36263655)
J Biol Chem. 2021 Sep;297(3):101068. (PMID: 34375638)
Neuropsychopharmacology. 2003 Apr;28(4):734-9. (PMID: 12655319)
Mol Cell Biol. 2008 May;28(9):3070-5. (PMID: 18316400)
Hypertens Res. 2015 Feb;38(2):155-62. (PMID: 25410879)
Sleep. 2013 Mar 01;36(3):431-46. (PMID: 23449886)
Int J Cancer. 2019 Oct 1;145(7):1745-1753. (PMID: 30665264)
Acta Biochim Biophys Sin (Shanghai). 2021 Oct 12;53(10):1257-1265. (PMID: 34415290)
Cancer Lett. 2020 Jan 28;469:498-509. (PMID: 31765736)
FEBS J. 2022 Nov;289(21):6589-6604. (PMID: 34657394)
Nature. 2004 Jul 22;430(6998):467-71. (PMID: 15269772)
Int J Mol Sci. 2019 Jan 15;20(2):. (PMID: 30650649)
Science. 2009 May 1;324(5927):651-4. (PMID: 19299583)
Sci Rep. 2015 May 19;5:10232. (PMID: 25989161)
Nat Genet. 2005 Feb;37(2):187-92. (PMID: 15665827)
Circulation. 2008 Apr 22;117(16):2087-95. (PMID: 18413500)
Cell Metab. 2016 Sep 13;24(3):462-473. (PMID: 27546460)
Handb Exp Pharmacol. 2013;(217):67-103. (PMID: 23604476)
Stroke. 2017 Sep;48(9):2565-2573. (PMID: 28747460)
J Physiol Sci. 2018 May;68(3):207-219. (PMID: 29460036)
Hepatology. 2015 Feb;61(2):497-505. (PMID: 25212631)
Cancer Manag Res. 2021 Dec 22;13:9329-9343. (PMID: 34992456)
Vessel Plus. 2018;2:. (PMID: 30101218)
J Biol Chem. 2013 Dec 20;288(51):36548-53. (PMID: 24196956)
Science. 2021 Jan 1;371(6524):. (PMID: 33384351)
Handb Exp Pharmacol. 2013;(217):379-88. (PMID: 23604488)
Heredity (Edinb). 2016 Sep;117(3):165-72. (PMID: 27301334)
J Neurosci. 2021 Feb 3;41(5):1046-1058. (PMID: 33268545)
Front Physiol. 2018 Mar 15;9:193. (PMID: 29662454)
Toxicol Lett. 2019 Oct 1;313:188-195. (PMID: 31284022)
Science. 2002 Dec 20;298(5602):2339-40. (PMID: 12493901)
PLoS One. 2009;4(3):e4882. (PMID: 19287494)
PLoS One. 2010 Apr 02;5(4):e10007. (PMID: 20368993)
J Huntingtons Dis. 2023;12(2):91-104. (PMID: 37125558)
J Inorg Biochem. 2012 Mar;108:188-95. (PMID: 22245004)
Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3450-5. (PMID: 17360665)
Science. 2009 May 1;324(5927):654-7. (PMID: 19286518)
Cell. 2006 May 5;125(3):497-508. (PMID: 16678094)
BMC Cancer. 2023 Mar 28;23(1):280. (PMID: 36978001)
FEBS J. 2005 Aug;272(16):4153-62. (PMID: 16098197)
Cell Mol Life Sci. 2015 Sep;72(17):3225-34. (PMID: 25972277)
IUBMB Life. 2004 Jun;56(6):309-15. (PMID: 15370879)
J Neurosci. 2021 Jan 20;41(3):502-512. (PMID: 33234609)
Cancer Res. 2009 Dec 15;69(24):9315-22. (PMID: 19934327)
Cold Spring Harb Symp Quant Biol. 2007;72:85-94. (PMID: 18419265)
Science. 2013 Nov 8;342(6159):727-30. (PMID: 24202171)
BMC Genomics. 2021 Apr 12;22(1):259. (PMID: 33845768)
Cold Spring Harb Perspect Biol. 2018 May 1;10(5):. (PMID: 28778867)
Nat Rev Genet. 2017 Mar;18(3):164-179. (PMID: 27990019)
Trends Cell Biol. 2014 Feb;24(2):90-9. (PMID: 23916625)
PLoS Genet. 2016 Feb 19;12(2):e1005882. (PMID: 26895328)
Oncotarget. 2017 Nov 11;8(62):105873-105881. (PMID: 29285299)
PLoS Genet. 2009 Apr;5(4):e1000442. (PMID: 19343201)
Front Genet. 2021 Jun 03;12:680528. (PMID: 34149816)
Epigenomics. 2012 Oct;4(5):537-49. (PMID: 23130835)
Proc Natl Acad Sci U S A. 2006 May 2;103(18):7118-23. (PMID: 16636276)
Curr Biol. 2013 Oct 21;23(20):1959-68. (PMID: 24094851)
PLoS One. 2010 Jan 01;5(1):e8561. (PMID: 20049328)
Int J Cancer. 2007 Jan 15;120(2):432-5. (PMID: 17096334)
Handb Exp Pharmacol. 2013;(217):29-44. (PMID: 23604474)
Genes Brain Behav. 2022 Sep;21(7):e12829. (PMID: 36053258)
J Physiol Pharmacol. 2013 Dec;64(6):761-72. (PMID: 24388891)
Science. 2005 Aug 26;309(5739):1390-4. (PMID: 16109848)
Front Biosci (Schol Ed). 2014 Jan 01;6(1):120-37. (PMID: 24389266)
Psychopharmacology (Berl). 2022 Oct;239(10):3185-3200. (PMID: 35915264)
J Biol Chem. 2005 Jun 3;280(22):21358-68. (PMID: 15797872)
Mol Ther Nucleic Acids. 2019 Dec 6;18:1009-1022. (PMID: 31778954)
J Cell Biol. 2016 Oct 10;215(1):15-25. (PMID: 27738003)
Nat Struct Mol Biol. 2017 Jan;24(1):15-22. (PMID: 27892932)
Biomed Res Int. 2022 Jul 4;2022:9774879. (PMID: 35832846)
J Cell Biochem. 2019 May;120(5):8731-8741. (PMID: 30536616)
Biochemistry. 2015 Jan 20;54(2):250-9. (PMID: 25526362)
Encephale. 2015 Sep;41(4 Suppl 1):S38-44. (PMID: 26746321)
Adv Exp Med Biol. 2021;1344:87-110. (PMID: 34773228)
فهرسة مساهمة: Keywords: NPAS2; PAS domain; circadian; heme; molecular clockwork; rhythmicity
تواريخ الأحداث: Date Created: 20231027 Latest Revision: 20231029
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10603908
DOI: 10.3390/biology12101354
PMID: 37887064
قاعدة البيانات: MEDLINE
الوصف
تدمد:2079-7737
DOI:10.3390/biology12101354