دورية أكاديمية
أعرض في EDS

Depression, anxiety, and quality of life as predictors of rehospitalization in patients with chronic heart failure.

التفاصيل البيبلوغرافية
العنوان: Depression, anxiety, and quality of life as predictors of rehospitalization in patients with chronic heart failure.
المؤلفون: Veskovic J; Department of Internal Medicine, Cardiology, CVK, Charité University Medicine Berlin, 13353, Berlin, Germany. jovan.veskovic@charite.de.; Scirent Clinical Research and Science, 13353, Berlin, Germany. jovan.veskovic@charite.de., Cvetkovic M; Department of Internal Medicine, Cardiology, CVK, Charité University Medicine Berlin, 13353, Berlin, Germany., Tahirovic E; Scirent Clinical Research and Science, 13353, Berlin, Germany., Zdravkovic M; Department of Cardiology, Faculty of Medicine, University Clinical Hospital Center Bezanijska Kosa, University of Belgrade, Belgrade, 11000, Serbia., Apostolovic S; Department for Cardiovascular Diseases, Clinical Centre Niš, University of Niš, Niš, 18000, Serbia., Kosevic D; Institute for Cardiovascular Diseases Dedinje, Department of Cardiology, Belgrade, 11000, Serbia., Loncar G; Institute for Cardiovascular Diseases Dedinje, Department of Cardiology, Belgrade, 11000, Serbia.; Faculty of Medicine, Department of Cardiology, University of Belgrade, University Clinical Center of Serbia, Belgrade, 11000, Serbia., Obradovic D; Heart Center of Leipzig, University of Leipzig, 04289, Leipzig, Germany., Matic D; Department of Cardiology, University Clinical Centre of Serbia, Belgrade, 11000, Serbia., Ignjatovic A; Faculty of Medicine, University of Niš, Niš, 18000, Serbia., Cvetkovic T; Faculty of Medicine, University of Niš, Niš, 18000, Serbia., Posch MG; Scirent Clinical Research and Science, 13353, Berlin, Germany., Radenovic S; Department of Internal Medicine, Cardiology, CVK, Charité University Medicine Berlin, 13353, Berlin, Germany., Ristić AD; Faculty of Medicine, Department of Cardiology, University of Belgrade, University Clinical Center of Serbia, Belgrade, 11000, Serbia., Dokic D; Scirent Clinical Research and Science, 13353, Berlin, Germany., Milošević N; Scirent Clinical Research and Science, 13353, Berlin, Germany., Panic N; Scirent Clinical Research and Science, 13353, Berlin, Germany., Düngen HD; Department of Internal Medicine, Cardiology, CVK, Charité University Medicine Berlin, 13353, Berlin, Germany. hans-dirk.duengen@charite.de.; German Centre for Cardiovascular Research (DZHK), Partner Site Berlin, 13353, Berlin, Germany. hans-dirk.duengen@charite.de.
المصدر: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2023 Oct 27; Vol. 23 (1), pp. 525. Date of Electronic Publication: 2023 Oct 27.
نوع المنشور: Observational Study; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Quality of Life* , Heart Failure*/diagnosis , Heart Failure*/therapy, Humans ; Depression/diagnosis ; Depression/epidemiology ; Depression/etiology ; Patient Readmission ; Prospective Studies ; Anxiety/diagnosis ; Anxiety/epidemiology ; Anxiety/etiology ; Chronic Disease ; Surveys and Questionnaires
مستخلص: Background: Chronic heart failure (CHF) is a severe condition, often co-occurring with depression and anxiety, that strongly affects the quality of life (QoL) in some patients. Conversely, depressive and anxiety symptoms are associated with a 2-3 fold increase in mortality risk and were shown to act independently of typical risk factors in CHF progression. The aim of this study was to examine the impact of depression, anxiety, and QoL on the occurrence of rehospitalization within one year after discharge in CHF patients.
Methods: 148 CHF patients were enrolled in a 10-center, prospective, observational study. All patients completed two questionnaires, the Hospital Anxiety and Depression Scale (HADS) and the Questionnaire Short Form Health Survey 36 (SF-36) at discharge timepoint.
Results: It was found that demographic and clinical characteristics are not associated with rehospitalization. Still, the levels of depression correlated with gender (p ≤ 0.027) and marital status (p ≤ 0.001), while the anxiety values ​​were dependent on the occurrence of chronic obstructive pulmonary disease (COPD). However, levels of depression (HADS-Depression) and anxiety (HADS-Anxiety) did not correlate with the risk of rehospitalization. Univariate logistic regression analysis results showed that rehospitalized patients had significantly lower levels of Bodily pain (BP, p = 0.014), Vitality (VT, p = 0.005), Social Functioning (SF, p = 0.007), and General Health (GH, p = 0.002). In the multivariate model, poor GH (OR 0.966, p = 0.005) remained a significant risk factor for rehospitalization, and poor General Health is singled out as the most reliable prognostic parameter for rehospitalization (AUC = 0.665, P = 0.002).
Conclusion: Taken together, our results suggest that QoL assessment complements clinical prognostic markers to identify CHF patients at high risk for adverse events.
Clinical Trial Registration: The study is registered under http://clinicaltrials.gov (NCT01501981, first posted on 30/12/2011), sponsored by Charité - Universitätsmedizin Berlin.
(© 2023. The Author(s).)
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فهرسة مساهمة: Keywords: Anxiety; Depression; Heart failure; Prediction; Quality of life; Rehospitalization
سلسلة جزيئية: ClinicalTrials.gov NCT01501981
تواريخ الأحداث: Date Created: 20231027 Date Completed: 20231030 Latest Revision: 20231031
رمز التحديث: 20231031
مُعرف محوري في PubMed: PMC10612261
DOI: 10.1186/s12872-023-03500-8
PMID: 37891464
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2261
DOI:10.1186/s12872-023-03500-8