تقرير
Symptomatic Hypocalcemia due to Nutritional Vitamin D Deficiency in Three Adolescents during the COVID-19 Pandemic.
العنوان: | Symptomatic Hypocalcemia due to Nutritional Vitamin D Deficiency in Three Adolescents during the COVID-19 Pandemic. |
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المؤلفون: | Sasidharan Pillai S; Division of Pediatric Endocrinology, Hasbro Children's Hospital, Providence, USA.; Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, USA., Topor LS; Division of Pediatric Endocrinology, Hasbro Children's Hospital, Providence, USA.; Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, USA. |
المصدر: | Case reports in pediatrics [Case Rep Pediatr] 2023 Oct 19; Vol. 2023, pp. 3588196. Date of Electronic Publication: 2023 Oct 19 (Print Publication: 2023). |
نوع المنشور: | Case Reports |
اللغة: | English |
بيانات الدورية: | Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101581030 Publication Model: eCollection Cited Medium: Print ISSN: 2090-6803 (Print) NLM ISO Abbreviation: Case Rep Pediatr Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: New York, NY : Hindawi Pub. Corp. |
مستخلص: | Background: Symptomatic hypocalcemia secondary to vitamin D deficiency (VDD) is rare among adolescents without underlying medical disorders, but its prevalence is higher in known risk populations. We report on three adolescent males with low nutritional intake of vitamin D and calcium and limited sun exposure who presented with hypocalcemic tetany and muscle cramps due to VDD during the COVID-19 pandemic. Case Reports . Three adolescent males (age range 14 to 16 years) presented with symptomatic hypocalcemia: paresthesia, carpopedal spasms, and muscle cramps. All reported limited dairy intake and sun exposure. Laboratory studies showed mean ionized calcium (iCa) 2.73 mg/dl (range 2.69-2.8), mean phosphorus 4.17 mg/dl (range, 3-5.4), mean parathyroid hormone (PTH) 431.67 pg/mL (range, 320-527), and mean 25-hydroxyvitamin D (25(OH)D) 7.37 ng/mL (range 5.3-10.8). All the patients presented during the COVID-19 pandemic, and one had COVID-19 infection. All were treated with oral calcium and high dose ergocalciferol. Patients 2 and 3 were also treated with intravenous calcium gluconate infusion and oral calcitriol. Conclusion: Severe VDD with symptomatic hypocalcemia can occur among adolescents without underlying medical diagnoses due to dietary and behavioral habits that limit nutritional intake and sun exposure. Risk factors of the patients may have been potentiated by pandemic-related behaviors such as more time indoors at home related to social distancing, as well as diets with limited nutrient intake. Adolescents presenting with nonspecific musculoskeletal symptoms should be screened for VDD and hypocalcemia. Appropriate treatment and preventive measures can stop immediate and long-term complications. Competing Interests: The authors declare that they have no conflicts of interest. (Copyright © 2023 Sabitha Sasidharan Pillai and Lisa Swartz Topor.) |
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تواريخ الأحداث: | Date Created: 20231030 Latest Revision: 20231031 |
رمز التحديث: | 20231031 |
مُعرف محوري في PubMed: | PMC10602705 |
DOI: | 10.1155/2023/3588196 |
PMID: | 37901796 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2090-6803 |
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DOI: | 10.1155/2023/3588196 |