دورية أكاديمية
Dietary approaches for controlling cancer by limiting the Warburg effect: a review.
| العنوان: | Dietary approaches for controlling cancer by limiting the Warburg effect: a review. |
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| المؤلفون: | Shimi G; Department of Cellular and Molecular Nutrition, Faculty of Nutrition Science and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. |
| المصدر: | Nutrition reviews [Nutr Rev] 2024 Sep 01; Vol. 82 (9), pp. 1281-1291. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0376405 Publication Model: Print Cited Medium: Internet ISSN: 1753-4887 (Electronic) Linking ISSN: 00296643 NLM ISO Abbreviation: Nutr Rev Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : Oxford Oxford University Press Original Publication: [Washington, D.C.] : International Life Sciences Institute |
| مواضيع طبية MeSH: | Neoplasms*/diet therapy , Warburg Effect, Oncologic*, Humans ; Diet/methods ; Glucose/metabolism ; Lactic Acid/metabolism |
| مستخلص: | Cancer is a mysterious disease. Among other alterations, tumor cells, importantly, have metabolic modifications. A well-known metabolic modification commonly observed in cancer cells has been termed the Warburg effect. This phenomenon is defined as a high preference for glucose uptake, and increased lactate production from that glucose, even when oxygen is readily available. Some anti-cancer drugs target the proposed Warburg effect, and some dietary regimens can function similarly. However, the most suitable dietary strategies for treating particular cancers are not yet well understood. The aim of this review was to describe findings regarding the impact of various proposed dietary regimens targeting the Warburg effect. The evidence suggests that combining routine cancer therapies with diet-based strategies may improve the outcome in treating cancer. However, designing individualized therapies must be our ultimate goal. (© The Author(s) 2023. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.) |
| فهرسة مساهمة: | Keywords: OXPHOS; cancer; diet; glycolysis; oxidative phosphorylation; the Warburg effect |
| المشرفين على المادة: | IY9XDZ35W2 (Glucose) 33X04XA5AT (Lactic Acid) |
| تواريخ الأحداث: | Date Created: 20231030 Date Completed: 20240812 Latest Revision: 20240812 |
| رمز التحديث: | 20240813 |
| DOI: | 10.1093/nutrit/nuad130 |
| PMID: | 37903372 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1753-4887 |
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| DOI: | 10.1093/nutrit/nuad130 |