دورية أكاديمية
Trends, clinical characteristics, antimicrobial susceptibility patterns, and outcomes of Campylobacter bacteraemia: a multicentre retrospective study.
| العنوان: | Trends, clinical characteristics, antimicrobial susceptibility patterns, and outcomes of Campylobacter bacteraemia: a multicentre retrospective study. |
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| المؤلفون: | Baek YJ; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.; Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea., Song JE; Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Republic of Korea., Kim EJ; Department of Infectious Diseases, Ajou University College of Medicine, Suwon, Republic of Korea., Choi H; National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea., Sohn Y; Department of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Republic of Korea., Jeon YD; Department of Internal Medicine, Kangwon National University College of Medicine, Chuncheon, Republic of Korea., Lee EH; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Ahn JY; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Jeong SJ; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Ku NS; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Choi JY; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Yeom JS; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Song YG; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim JH; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. qetu1111@yuhs.ac. |
| المصدر: | Infection [Infection] 2024 Jun; Vol. 52 (3), pp. 857-864. Date of Electronic Publication: 2023 Nov 01. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Heidelberg Country of Publication: Germany NLM ID: 0365307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0973 (Electronic) Linking ISSN: 03008126 NLM ISO Abbreviation: Infection Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2011- : Heidelberg : Springer Heidelberg Original Publication: München, Verlagsgesellschaft Otto Spatz. |
| مواضيع طبية MeSH: | Bacteremia*/microbiology , Bacteremia*/mortality , Bacteremia*/epidemiology , Bacteremia*/drug therapy , Campylobacter Infections*/microbiology , Campylobacter Infections*/epidemiology , Campylobacter Infections*/drug therapy , Campylobacter Infections*/mortality , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/therapeutic use, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Aged ; Adult ; Drug Resistance, Bacterial ; Microbial Sensitivity Tests ; Campylobacter/drug effects ; Aged, 80 and over ; Campylobacter jejuni/drug effects ; Risk Factors ; Young Adult ; Hospital Mortality |
| مستخلص: | Purpose: We aimed to explore the clinical characteristics of Campylobacter bacteraemia and identify the trends, risk factors for mortality, and antimicrobial susceptibility patterns from clinical samples. Methods: This retrospective cohort study included patients confirmed to have Campylobacter bacteraemia from seven hospitals between January 2010 and June 2021. Data on demographics and underlying history, clinical manifestation, and antimicrobial susceptibility patterns were collected and analyzed. Annual cases of Campylobacter enteritis were extracted from a public database. Results: A total of 108 patients were included, and five species were isolated. Campylobacter jejuni accounted for 54 (50.0%) cases and 17 (16%) patients had no symptoms other than fever. In-hospital mortality occurred in 14 (13.0%) patients. C. jejuni bacteraemia was associated with lower mortality compared to non-C. jejuni bacteraemia. Underlying cancer and septic shock were the significant factors associated with in-hospital mortality. Quinolone resistance was high (59%), whereas only 4% of isolates exhibited macrolide resistance. There has been a significant increase in the number of Campylobacter enteritis cases, which was strongly correlated with the number of Campylobacter bacteraemia cases (Pearson's coefficient: 0.953; p < 0.0001). Conclusion: The notably increasing incidence of Campylobacter bacteraemia and antibiotic resistance patterns can challenge the treatment, necessitating collective efforts of national surveillance and networks by many departments. (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.) |
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| فهرسة مساهمة: | Keywords: Bacteraemia; Campylobacter infection; One health; Risk factors; Trends |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20231101 Date Completed: 20240531 Latest Revision: 20240815 |
| رمز التحديث: | 20240815 |
| DOI: | 10.1007/s15010-023-02118-4 |
| PMID: | 37910310 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1439-0973 |
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| DOI: | 10.1007/s15010-023-02118-4 |