دورية أكاديمية
Trends, clinical characteristics, antimicrobial susceptibility patterns, and outcomes of Campylobacter bacteraemia: a multicentre retrospective study.
العنوان: | Trends, clinical characteristics, antimicrobial susceptibility patterns, and outcomes of Campylobacter bacteraemia: a multicentre retrospective study. |
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المؤلفون: | Baek YJ; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.; Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea., Song JE; Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Republic of Korea., Kim EJ; Department of Infectious Diseases, Ajou University College of Medicine, Suwon, Republic of Korea., Choi H; National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea., Sohn Y; Department of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Republic of Korea., Jeon YD; Department of Internal Medicine, Kangwon National University College of Medicine, Chuncheon, Republic of Korea., Lee EH; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Ahn JY; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Jeong SJ; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Ku NS; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Choi JY; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Yeom JS; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Song YG; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim JH; Division of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. qetu1111@yuhs.ac. |
المصدر: | Infection [Infection] 2024 Jun; Vol. 52 (3), pp. 857-864. Date of Electronic Publication: 2023 Nov 01. |
نوع المنشور: | Journal Article; Multicenter Study |
اللغة: | English |
بيانات الدورية: | Publisher: Springer Heidelberg Country of Publication: Germany NLM ID: 0365307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0973 (Electronic) Linking ISSN: 03008126 NLM ISO Abbreviation: Infection Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2011- : Heidelberg : Springer Heidelberg Original Publication: München, Verlagsgesellschaft Otto Spatz. |
مواضيع طبية MeSH: | Bacteremia*/microbiology , Bacteremia*/mortality , Bacteremia*/epidemiology , Bacteremia*/drug therapy , Campylobacter Infections*/microbiology , Campylobacter Infections*/epidemiology , Campylobacter Infections*/drug therapy , Campylobacter Infections*/mortality , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/therapeutic use, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Aged ; Adult ; Drug Resistance, Bacterial ; Microbial Sensitivity Tests ; Campylobacter/drug effects ; Aged, 80 and over ; Campylobacter jejuni/drug effects ; Risk Factors ; Young Adult ; Hospital Mortality |
مستخلص: | Purpose: We aimed to explore the clinical characteristics of Campylobacter bacteraemia and identify the trends, risk factors for mortality, and antimicrobial susceptibility patterns from clinical samples. Methods: This retrospective cohort study included patients confirmed to have Campylobacter bacteraemia from seven hospitals between January 2010 and June 2021. Data on demographics and underlying history, clinical manifestation, and antimicrobial susceptibility patterns were collected and analyzed. Annual cases of Campylobacter enteritis were extracted from a public database. Results: A total of 108 patients were included, and five species were isolated. Campylobacter jejuni accounted for 54 (50.0%) cases and 17 (16%) patients had no symptoms other than fever. In-hospital mortality occurred in 14 (13.0%) patients. C. jejuni bacteraemia was associated with lower mortality compared to non-C. jejuni bacteraemia. Underlying cancer and septic shock were the significant factors associated with in-hospital mortality. Quinolone resistance was high (59%), whereas only 4% of isolates exhibited macrolide resistance. There has been a significant increase in the number of Campylobacter enteritis cases, which was strongly correlated with the number of Campylobacter bacteraemia cases (Pearson's coefficient: 0.953; p < 0.0001). Conclusion: The notably increasing incidence of Campylobacter bacteraemia and antibiotic resistance patterns can challenge the treatment, necessitating collective efforts of national surveillance and networks by many departments. (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.) |
References: | WHO. Campylobacter, https://www.who.int/news-room/fact-sheets/detail/campylobacter . Accessed 20 Jul 2023. CDC Foodborne Disease Active Surveillance Network (FoodNet), https://wwwn.cdc.gov/foodnetfast/ Accessed 20 Jul 2023. Ray LCCJ, Griffin PM. Decreased incidence of infections caused by pathogens transmitted commonly through food during the COVID-19 pandemic—foodborne diseases active surveillance network, 10 US Sites, 2017–2020. MMWR Morb Mortal Wkly Rep. 2021;70:1332–6. https://doi.org/10.15585/mmwr.mm7038a4 . (PMID: 10.15585/mmwr.mm7038a4345550028459900) de Miguel BR, Trigo E, De La Calle-Prieto F, Arsuaga M, Díaz-Menéndez M. Social distancing to combat COVID-19 led to a marked decrease in food-borne infections and sexually transmitted diseases in Spain. J Travel Med. 2020;27:taaa134. https://doi.org/10.1093/jtm/taaa134 . (PMID: 10.1093/jtm/taaa134) Ahn SY, Park JY, Lim IS, Chae SA, Yun SW, Lee NM, et al. Changes in the occurrence of gastrointestinal infections after COVID-19 in Korea. J Korean Med Sci. 2021. https://doi.org/10.3346/jkms.2021.36.e180 . (PMID: 10.3346/jkms.2021.36.e180349314968763880) Nielsen H, Hansen KK, Gradel KO, Kristensen B, Ejlertsen T, Østergaard C, et al. Bacteraemia as a result of Campylobacter species: a population-based study of epidemiology and clinical risk factors. Clin Microbiol Infect. 2010;16:57–61. https://doi.org/10.1111/j.1469-0691.2009.02900.x . (PMID: 10.1111/j.1469-0691.2009.02900.x19673969) Alfredson DA, Korolik V. Antibiotic resistance and resistance mechanisms in Campylobacter jejuni and Campylobacter coli. FEMS Microbiol Lett. 2007;277:123–32. https://doi.org/10.1111/j.1574-6968.2007.00935.x . (PMID: 10.1111/j.1574-6968.2007.00935.x18031331) Kim YJ, Park KH, Park DA, Park J, Bang BW, Lee SS, et al. Guideline for the antibiotic use in acute gastroenteritis. Infect Chemother. 2019;51:217–43. https://doi.org/10.3947/ic.2019.51.2.217 . (PMID: 10.3947/ic.2019.51.2.217312710036609748) Post A, Martiny D, van Waterschoot N, Hallin M, Maniewski U, Bottieau E, et al. Antibiotic susceptibility profiles among Campylobacter isolates obtained from international travelers between 2007 and 2014. Eur J Clin Microbiol Infect Dis. 2017;36:2101–7. (PMID: 10.1007/s10096-017-3032-6286235505653722) HIRA, https://opendata.hira.or.kr/op/opc/olap4thDsInfoTab1.do Accessed 20 Jul 2023. The European Committee on Antimicrobial Susceptibility Testing. Breakpoint tables for interpretation of MICs and zone diameters. Version 12.0, 2022. Costa D, Iraola G. Pathogenomics of emerging Campylobacter Species. Clin Microbiol Rev. 2019;32:e00072-e118. https://doi.org/10.1128/CMR.00072-18 . (PMID: 10.1128/CMR.00072-18312701266750134) Dearlove BL, Cody AJ, Pascoe B, Méric G, Wilson DJ, Sheppard SK. Rapid host switching in generalist Campylobacter strains erodes the signal for tracing human infections. ISME J. 2016;10:721–9. https://doi.org/10.1038/ismej.2015.149 . (PMID: 10.1038/ismej.2015.14926305157) Liu F, Ma R, Wang Y, Zhang L. The clinical importance of campylobacter concisus and other human hosted Campylobacter species. Front Cell Infect Microbiol. 2018;8:243. https://doi.org/10.3389/fcimb.2018.00243 . (PMID: 10.3389/fcimb.2018.00243300878576066527) Liao CH, Chuang CY, Huang YT, Lee PI, Hsueh PR. Bacteremia caused by antimicrobial resistant Campylobacter species at a medical center in Taiwan, 1998–2008. J Infect. 2012;65(5):392–9. https://doi.org/10.1016/j.jinf.2012.06.014 . (PMID: 10.1016/j.jinf.2012.06.01422771419) Pacanowski J, Lalande V, Lacombe K, Boudraa C, Lesprit P, Legrand P, et al. Campylobacter bacteremia: clinical features and factors associated with fatal outcome. Clin Infect Dis. 2008;47:790–6. https://doi.org/10.1086/591530 . (PMID: 10.1086/59153018699745) Tinévez C, Velardo F, Ranc AG, Dubois D, Pailhoriès H, Codde C, et al. Retrospective multicentric study on Campylobacter spp. Bacteremia in France: the Campylobacteremia study. Clin Infect Dis. 2022;75:702–9. https://doi.org/10.1093/cid/ciab983 . (PMID: 10.1093/cid/ciab98334849656) Francois Watkins LK, Laughlin ME, Joseph LA, Chen JC, Nichols M, Basler C, et al. Ongoing outbreak of extensively drug-resistant Campylobacter jejuni infections associated with US pet store puppies, 2016–2020. JAMA Netw Open. 2021;4:e2125203. https://doi.org/10.1001/jamanetworkopen.2021.25203 . (PMID: 10.1001/jamanetworkopen.2021.25203345244348444031) Kuhn KG, Nygård KM, Guzman-Herrador B, Sunde LS, Rimhanen-Finne R, Trönnberg L, et al. Campylobacter infections expected to increase due to climate change in Northern Europe. Sci Rep. 2020;10:13874. https://doi.org/10.1038/s41598-020-70593-y . (PMID: 10.1038/s41598-020-70593-y328078107431569) Ravel A, Pintar K, Nesbitt A, Pollari F. Non food-related risk factors of campylobacteriosis in Canada: a matched case-control study. BMC Public Health. 2016;16:1016. https://doi.org/10.1186/s12889-016-3679-4 . (PMID: 10.1186/s12889-016-3679-4276773385039884) Cho H, Lee SH, Lee JH, Lee SJ, Park SC. Epidemiologic and clinical features of Campylobacter enteritis before and during COVID-19 in Korea. J Korean Med Sci. 2023;38: e67. https://doi.org/10.3346/jkms.2023.38.e67 . (PMID: 10.3346/jkms.2023.38.e67368801089988435) Ternhag A, Asikainen T, Giesecke J, Ekdahl K. A meta-analysis on the effects of antibiotic treatment on duration of symptoms caused by infection with Campylobacter species. Clin Infect Dis. 2007;44:696–700. https://doi.org/10.1086/509924 . (PMID: 10.1086/50992417278062) Yoon JG, Lee SN, Hyun HJ, Choi MJ, Jeon JH, Jung E, et al. Campylobacter jejuni Bacteremia in a liver cirrhosis patient and review of literature: a case study. Infect Chemother. 2017;49:230–5. https://doi.org/10.3947/ic.2017.49.3.230 . (PMID: 10.3947/ic.2017.49.3.230286086615620392) Park SH, Kim BJ, Kwon YH, Hwang IY, Sung GH, Park EH, et al. Antimicrobial susceptibility and genetic analysis of Campylobacter jejuni isolated from diarrhea patients in Busan. Ann Clin Microbiol. 2019;22(2):42–9. https://doi.org/10.5145/ACM.2019.22.2.42 . (PMID: 10.5145/ACM.2019.22.2.42) Gahamanyi N, Song DG, Yoon KY, Mboera LEG, Matee MI, Mutangana D, et al. Antimicrobial resistance profiles, virulence genes, and genetic diversity of thermophilic Campylobacter species isolated from a layer poultry farm in Korea. Front Microbiol. 2021;12: 622275. https://doi.org/10.3389/fmicb.2021.622275 . (PMID: 10.3389/fmicb.2021.622275338596248043113) Oh JY, Kwon YK, Wei B, Jang HK, Lim SK, Kim CH, et al. Epidemiological relationships of Campylobacter jejuni strains isolated from humans and chickens in South Korea. J Microbiol. 2017;55:13–20. https://doi.org/10.1007/s12275-017-6308-8 . (PMID: 10.1007/s12275-017-6308-828035601) Khademi F, Sahebkar A. Prevalence of fluoroquinolone-resistant campylobacter species in Iran: a systematic review and meta-analysis. Int J Microbiol. 2020;2020:8868197. https://doi.org/10.1155/2020/8868197 . (PMID: 10.1155/2020/8868197334887287803110) The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2019–2020. EFSA J. 2022;20:e07209. https://doi.org/10.2903/j.efsa.2022.7209 . Park M, Kim J, Feinstein J, Lang KS, Ryu S, Jeon B. Development of fluoroquinolone resistance through antibiotic tolerance in Campylobacter jejuni. Microbiol Spectr. 2022;10: e0166722. https://doi.org/10.1128/spectrum.01667-22 . (PMID: 10.1128/spectrum.01667-2236066254) Goyal D, Watkins LKF, Montgomery MP, Jones SMB, Caidi H, Friedman CR. Antimicrobial susceptibility testing and successful treatment of hospitalised patients with extensively drug-resistant Campylobacter jejuni infections linked to a pet store puppy outbreak. J Glob Antimicrob Resist. 2021;26:84–90. https://doi.org/10.1016/j.jgar.2021.04.029 . (PMID: 10.1016/j.jgar.2021.04.029340489798448951) Heimesaat MM, Backert S, Alter T, Bereswill S. Human Campylobacteriosis—a serious infectious threat in a one health perspective. Curr Top Microbiol Immunol. 2021;431:1–23. https://doi.org/10.1007/978-3-030-65481-8_1 . (PMID: 10.1007/978-3-030-65481-8_133620646) |
فهرسة مساهمة: | Keywords: Bacteraemia; Campylobacter infection; One health; Risk factors; Trends |
المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
تواريخ الأحداث: | Date Created: 20231101 Date Completed: 20240531 Latest Revision: 20240815 |
رمز التحديث: | 20240815 |
DOI: | 10.1007/s15010-023-02118-4 |
PMID: | 37910310 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1439-0973 |
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DOI: | 10.1007/s15010-023-02118-4 |