دورية أكاديمية
Community transmission of SARS-CoV-2 during the Delta wave in New York City.
| العنوان: | Community transmission of SARS-CoV-2 during the Delta wave in New York City. |
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| المؤلفون: | Dai K; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th St, New York, NY, 10032, USA.; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Foerster S; New York City Department of Health and Mental Hygiene (DOHMH), Long Island City, NY, 11001, USA., Vora NM; New York City Department of Health and Mental Hygiene (DOHMH), Long Island City, NY, 11001, USA., Blaney K; New York City Department of Health and Mental Hygiene (DOHMH), Long Island City, NY, 11001, USA., Keeley C; New York City Department of Health and Mental Hygiene (DOHMH), Long Island City, NY, 11001, USA., Hendricks L; New York City Department of Health and Mental Hygiene (DOHMH), Long Island City, NY, 11001, USA., Varma JK; Department of Population Health Sciences, Weill Cornell Medical College, New York, NY, 10065, USA., Long T; NYC Health + Hospitals, New York, NY, USA.; Department of Population Health, New York University, New York, NY, 10016, USA., Shaman J; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th St, New York, NY, 10032, USA.; Columbia Climate School, Columbia University, New York, NY, 10025, USA., Pei S; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th St, New York, NY, 10032, USA. sp3449@cumc.columbia.edu. |
| المصدر: | BMC infectious diseases [BMC Infect Dis] 2023 Nov 02; Vol. 23 (1), pp. 753. Date of Electronic Publication: 2023 Nov 02. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, [2001- |
| مواضيع طبية MeSH: | COVID-19*/epidemiology , Coinfection*, Humans ; SARS-CoV-2 ; New York City/epidemiology |
| مستخلص: | Background: Understanding community transmission of SARS-CoV-2 variants of concern (VOCs) is critical for disease control in the post pandemic era. The Delta variant (B.1.617.2) emerged in late 2020 and became the dominant VOC globally in the summer of 2021. While the epidemiological features of the Delta variant have been extensively studied, how those characteristics shaped community transmission in urban settings remains poorly understood. Methods: Using high-resolution contact tracing data and testing records, we analyze the transmission of SARS-CoV-2 during the Delta wave within New York City (NYC) from May 2021 to October 2021. We reconstruct transmission networks at the individual level and across 177 ZIP code areas, examine network structure and spatial spread patterns, and use statistical analysis to estimate the effects of factors associated with COVID-19 spread. Results: We find considerable individual variations in reported contacts and secondary infections, consistent with the pre-Delta period. Compared with earlier waves, Delta-period has more frequent long-range transmission events across ZIP codes. Using socioeconomic, mobility and COVID-19 surveillance data at the ZIP code level, we find that a larger number of cumulative cases in a ZIP code area is associated with reduced within- and cross-ZIP code transmission and the number of visitors to each ZIP code is positively associated with the number of non-household infections identified through contact tracing and testing. Conclusions: The Delta variant produced greater long-range spatial transmission across NYC ZIP code areas, likely caused by its increased transmissibility and elevated human mobility during the study period. Our findings highlight the potential role of population immunity in reducing transmission of VOCs. Quantifying variability of immunity is critical for identifying subpopulations susceptible to future VOCs. In addition, non-pharmaceutical interventions limiting human mobility likely reduced SARS-CoV-2 spread over successive pandemic waves and should be encouraged for reducing transmission of future VOCs. (© 2023. The Author(s).) |
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| معلومات مُعتمدة: | R01AI163023 United States NH NIH HHS; NU38OT000297 United States CC CDC HHS; U01 CK000592 United States CK NCEZID CDC HHS; U01CK000592 United States CC CDC HHS; U01CK000592 United States ACL ACL HHS; R01 AI163023 United States AI NIAID NIH HHS |
| فهرسة مساهمة: | Keywords: Community transmission; Contact tracing; Delta variant; SARS-CoV-2; Transmission networks |
| SCR Organism: | SARS-CoV-2 variants |
| تواريخ الأحداث: | Date Created: 20231102 Date Completed: 20231103 Latest Revision: 20240228 |
| رمز التحديث: | 20240228 |
| مُعرف محوري في PubMed: | PMC10621074 |
| DOI: | 10.1186/s12879-023-08735-6 |
| PMID: | 37915079 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1471-2334 |
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| DOI: | 10.1186/s12879-023-08735-6 |