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An accident waiting to happen? Exposing the potential of urogenital schistosomiasis transmission in the Lake Albert region, Uganda.

التفاصيل البيبلوغرافية
العنوان: An accident waiting to happen? Exposing the potential of urogenital schistosomiasis transmission in the Lake Albert region, Uganda.
المؤلفون: Tumusiime J; Department of Biology, Mbarara University of Science and Technology, Mbarara, Uganda. jtumusiime90@must.ac.ug.; Institute of Animal Ecology and Systematics, Justus Liebig University Giessen, Giessen, Germany. jtumusiime90@must.ac.ug., Kagoro-Rugunda G; Department of Biology, Mbarara University of Science and Technology, Mbarara, Uganda., Tolo CU; Department of Biology, Mbarara University of Science and Technology, Mbarara, Uganda., Namirembe D; Department of Biology, Mbarara University of Science and Technology, Mbarara, Uganda., Schols R; Department of Biology, Royal Museum for Central Africa, Tervuren, Belgium.; Laboratory of Aquatic Biology, KU Leuven, Campus Kortrijk, Kortrijk, Belgium., Hammoud C; Department of Biology, Royal Museum for Central Africa, Tervuren, Belgium.; Department of Biology, Ghent University, Ghent, Belgium., Albrecht C; Department of Biology, Mbarara University of Science and Technology, Mbarara, Uganda.; Institute of Animal Ecology and Systematics, Justus Liebig University Giessen, Giessen, Germany., Huyse T; Department of Biology, Royal Museum for Central Africa, Tervuren, Belgium.
المصدر: Parasites & vectors [Parasit Vectors] 2023 Nov 03; Vol. 16 (1), pp. 398. Date of Electronic Publication: 2023 Nov 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central
مواضيع طبية MeSH: Schistosomiasis haematobia*, Animals ; Humans ; Lakes ; Uganda/epidemiology ; Schistosoma haematobium/genetics ; Bulinus/parasitology
مستخلص: Background: Urogenital schistosomiasis caused by the parasitic blood fluke Schistosoma haematobium is the most common form of that constitutes a majority of over 240 million schistosomiasis cases. The enigmatic absence of urogenital schistosomiasis in Uganda has, until now, been attributed to the absence of substantial populations of suitable snail intermediate hosts.
Methods: Malacological surveys were carried out in 73 sites southeast of Lake Albert, Uganda in October and November 2020. Collected snails were transported to the laboratory for identification. The snails were identified using partial mitochondrial cytochrome c oxidase subunit one and nuclear internal transcribed spacer barcoding. Schistosome infections in snails were also assessed using cercarial shedding and rapid diagnostic PCR techniques.
Results: We found Bulinus globosus and Bulinus nasutus productus, the main intermediate species in the transmission of S. haematobium in mainland East Africa. In this survey, B. globosus was more common than B. nasutus productus, with the former reported at four sites (total count = 188) and the latter reported at one site (total count = 79). Molecular testing revealed a high prevalence of Schistosoma bovis in B. nasutus productus (16%), but no S. haematobium infections were found.
Conclusions: Given the abundance of snail hosts and the risky human water contact behaviours observed, we highlight the potential for urogenital schistosomiasis transmission in the region.
(© 2023. The Author(s).)
References: Mol Biol Evol. 2018 Jun 1;35(6):1547-1549. (PMID: 29722887)
Parasitology. 2017 Jan;144(1):65-80. (PMID: 27572906)
J Mol Evol. 1985;22(2):160-74. (PMID: 3934395)
East Afr Med J. 1968 May;45(5):295-308. (PMID: 5674009)
Mol Biochem Parasitol. 1994 Jan;63(1):153-6. (PMID: 8183315)
Trans R Soc Trop Med Hyg. 1951 Apr;44(5):501-14. (PMID: 14835789)
Parasitol Res. 2020 Jul;119(7):2189-2205. (PMID: 32468189)
Trans R Soc Trop Med Hyg. 2019 Nov 1;113(11):722-729. (PMID: 31369105)
Parasit Vectors. 2008 Jun 10;1(1):15. (PMID: 18544153)
Sci Rep. 2022 Mar 30;12(1):5357. (PMID: 35354876)
Mol Mar Biol Biotechnol. 1994 Oct;3(5):294-9. (PMID: 7881515)
Emerg Infect Dis. 2019 Mar;25(3):613-615. (PMID: 30602122)
Ecosphere. 2022 Apr;13(4):. (PMID: 36285193)
Trop Med Infect Dis. 2021 Jun 22;6(3):. (PMID: 34206495)
PLoS Negl Trop Dis. 2022 Jul 5;16(7):e0010585. (PMID: 35788199)
Ann Soc Belg Med Trop. 1990 Sep;70(3):173-80. (PMID: 2122819)
PLoS Negl Trop Dis. 2023 Feb 10;17(2):e0010752. (PMID: 36763676)
PLoS Pathog. 2009 Sep;5(9):e1000571. (PMID: 19730700)
Parasit Vectors. 2019 Nov 27;12(1):565. (PMID: 31775865)
PLoS Negl Trop Dis. 2019 Aug 14;13(8):e0007617. (PMID: 31412023)
Acta Trop. 2018 Sep;185:412-418. (PMID: 29935144)
Infect Dis Poverty. 2020 Aug 31;9(1):121. (PMID: 32867849)
Data Brief. 2018 Sep 06;20:991-998. (PMID: 30225313)
معلومات مُعتمدة: B2/191/P1/MicroResist BRAIN-be 2.0 under the MicroResist project
فهرسة مساهمة: Keywords: Bulinus globosus; Bulinus nasutus productus; Emerging disease; Lake Albert; Schistosoma haematobium; Schistosomiasis
تواريخ الأحداث: Date Created: 20231103 Date Completed: 20231106 Latest Revision: 20231106
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10623741
DOI: 10.1186/s13071-023-06017-3
PMID: 37919743
قاعدة البيانات: MEDLINE
الوصف
تدمد:1756-3305
DOI:10.1186/s13071-023-06017-3