دورية أكاديمية
Ranavirus (Frog Virus 3) Infection in Free-Living Three-Toed Box Turtles (Terrapene mexicana triunguis) in Missouri, USA.
| العنوان: | Ranavirus (Frog Virus 3) Infection in Free-Living Three-Toed Box Turtles (Terrapene mexicana triunguis) in Missouri, USA. |
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| المؤلفون: | Apakupakul K; Saint Louis Zoo Institute for Conservation Medicine, 1 Government Dr., St. Louis, Missouri 63110, USA., Duncan M; Saint Louis Zoo Department of Animal Health, 1 Government Dr., St. Louis, Missouri 63110, USA., Subramaniam K; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, 2187 Mowry Rd., Bldg. 0471, Gainesville, Florida 32611, USA.; Emerging Pathogens Institute, University of Florida, 2055 Mowry Rd., Gainesville, Florida 32610, USA., Brenn-White M; Saint Louis Zoo Institute for Conservation Medicine, 1 Government Dr., St. Louis, Missouri 63110, USA., Palmer JL; Saint Louis Zoo Institute for Conservation Medicine, 1 Government Dr., St. Louis, Missouri 63110, USA., Viadanna PHO; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, 2187 Mowry Rd., Bldg. 0471, Gainesville, Florida 32611, USA.; Emerging Pathogens Institute, University of Florida, 2055 Mowry Rd., Gainesville, Florida 32610, USA., Vann JA; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, 2187 Mowry Rd., Bldg. 0471, Gainesville, Florida 32611, USA.; Emerging Pathogens Institute, University of Florida, 2055 Mowry Rd., Gainesville, Florida 32610, USA., Adamovicz L; Wildlife Epidemiology Laboratory, University of Illinois College of Veterinary Medicine, 2001 S. Lincoln Ave., Urbana, Illinois 61802, USA., Waltzek TB; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, 2187 Mowry Rd., Bldg. 0471, Gainesville, Florida 32611, USA.; Emerging Pathogens Institute, University of Florida, 2055 Mowry Rd., Gainesville, Florida 32610, USA.; Current affiliation: Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, P.O. Box 647034, Pullman, Washington, USA., Deem SL; Saint Louis Zoo Institute for Conservation Medicine, 1 Government Dr., St. Louis, Missouri 63110, USA. |
| المصدر: | Journal of wildlife diseases [J Wildl Dis] 2024 Jan 01; Vol. 60 (1), pp. 151-163. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wildlife Disease Association Country of Publication: United States NLM ID: 0244160 Publication Model: Print Cited Medium: Internet ISSN: 1943-3700 (Electronic) Linking ISSN: 00903558 NLM ISO Abbreviation: J Wildl Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Lawrence, KS : Wildlife Disease Association Original Publication: Ames, Iowa, Wildlife Disease Assn. |
| مواضيع طبية MeSH: | Turtles* , Ranavirus* , Nucleic Acids* , DNA Virus Infections*/veterinary, Animals ; Missouri/epidemiology ; Animals, Wild |
| مستخلص: | Frog virus 3 (FV3) and related ranaviruses are emerging infectious disease threats to ectothermic vertebrate species globally. Although the impact of these viruses on amphibian health is relatively well studied, less is understood about their effects on reptile health. We report two cases of FV3 infection, 11 mo apart, in three-toed box turtles (Terrapene mexicana triunguis) from a wildlife rehabilitation center. Case 1 had upper respiratory signs upon intake but had no clinical signs at the time of euthanasia 1 mo later. Case 2 presented for vehicular trauma, had ulcerative pharyngitis and glossitis, and died overnight. In case 1, we detected FV3 nucleic acid with qPCR in oral swabs, kidney, liver, spleen, and tongue. In case 2, we detected FV3 in an oral swab, an oral plaque, heart, kidney, lung, liver, spleen, and tongue. We also detected FV3 nucleic acid with in situ hybridization for case 2. For both cases, FV3 was isolated in cell culture and identified with DNA sequencing. Histopathologic examination of postmortem tissue from case 1 was unremarkable, whereas acute hemorrhagic pneumonia and splenic necrosis were noted in case 2. The difference in clinical signs between the two cases may have been due to differences in the temporal course of FV3 disease at the time of necropsy. Failure to detect this infection previously in Missouri reptiles may be due to lack of surveillance, although cases may also represent a novel spillover to box turtles in Missouri. Our findings reiterate previous suggestions that the range of FV3 infection may be greater than previously documented and that infection may occur in host species yet to be tested. (© Wildlife Disease Association 2024.) |
| فهرسة مساهمة: | Keywords: in situ hybridization; Box turtle; FV3; chelonian; ranavirus; reptile; surveillance; transmission |
| المشرفين على المادة: | 0 (Nucleic Acids) |
| تواريخ الأحداث: | Date Created: 20231103 Date Completed: 20240105 Latest Revision: 20240423 |
| رمز التحديث: | 20240423 |
| DOI: | 10.7589/JWD-D-23-00057 |
| PMID: | 37921651 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1943-3700 |
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| DOI: | 10.7589/JWD-D-23-00057 |