دورية أكاديمية
Selection for antimicrobial resistance in the plastisphere.
| العنوان: | Selection for antimicrobial resistance in the plastisphere. |
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| المؤلفون: | Stevenson EM; European Centre for Environment and Human Health, Environment and Sustainability Institute, University of Exeter Medical School, Faculty of Health and Life Sciences, Penryn Campus, Cornwall, UK; Marine Ecology & Biodiversity, Plymouth Marine Laboratory, Prospect Place, West Hoe, Plymouth PL1 3DH, UK; Faculty of Environment, Science and Economy, University of Exeter, Penryn Campus, Cornwall TR10 9FE, UK., Buckling A; Faculty of Environment, Science and Economy, University of Exeter, Penryn Campus, Cornwall TR10 9FE, UK., Cole M; Marine Ecology & Biodiversity, Plymouth Marine Laboratory, Prospect Place, West Hoe, Plymouth PL1 3DH, UK., Lindeque PK; Marine Ecology & Biodiversity, Plymouth Marine Laboratory, Prospect Place, West Hoe, Plymouth PL1 3DH, UK; Faculty of Environment, Science and Economy, University of Exeter, Penryn Campus, Cornwall TR10 9FE, UK., Murray AK; European Centre for Environment and Human Health, Environment and Sustainability Institute, University of Exeter Medical School, Faculty of Health and Life Sciences, Penryn Campus, Cornwall, UK. Electronic address: a.k.murray@exeter.ac.uk. |
| المصدر: | The Science of the total environment [Sci Total Environ] 2024 Jan 15; Vol. 908, pp. 168234. Date of Electronic Publication: 2023 Nov 02. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1026 (Electronic) Linking ISSN: 00489697 NLM ISO Abbreviation: Sci Total Environ Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam, Elsevier. |
| مواضيع طبية MeSH: | Anti-Bacterial Agents*/pharmacology , Drug Resistance, Bacterial*/genetics, Animals ; Humans ; Microplastics ; Plastics ; Commerce |
| مستخلص: | Microplastics and antimicrobials are widespread contaminants that threaten global systems and frequently co-exist in the presence of human or animal pathogens. Whilst the impact of each of these contaminants has been studied in isolation, the influence of this co-occurrence in driving antimicrobial resistance (AMR) 1 in microplastic-adhered microbial communities, known as 'the Plastisphere', is not well understood. This review proposes the mechanisms by which interactions between antimicrobials and microplastics may drive selection for AMR in the Plastisphere. These include: 1) increased rates of horizontal gene transfer in the Plastisphere compared with free-living counterparts and natural substrate controls due to the proximity of cells, co-occurrence of environmental microplastics with AMR selective compounds and the sequestering of extracellular antibiotic resistance genes in the biofilm matrix. 2) An elevated AMR selection pressure in the Plastisphere due to the adsorbing of AMR selective or co-selective compounds to microplastics at concentrations greater than those found in surrounding mediums and potentially those adsorbed to comparator particles. 3) AMR selection pressure may be further elevated in the Plastisphere due to the incorporation of antimicrobial or AMR co-selective chemicals in the plastic matrix during manufacture. Implications for both ecological functioning and environmental risk assessments are discussed, alongside recommendations for further research. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2023. Published by Elsevier B.V.) |
| فهرسة مساهمة: | Keywords: Antimicrobial resistance; Biofilm; Evolution; Microplastic; Plastisphere; Pollution |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (Microplastics) 0 (Plastics) |
| تواريخ الأحداث: | Date Created: 20231104 Date Completed: 20231127 Latest Revision: 20231127 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.scitotenv.2023.168234 |
| PMID: | 37924893 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-1026 |
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| DOI: | 10.1016/j.scitotenv.2023.168234 |