دورية أكاديمية
Antiviral potency of lupane and oleanane alkynyl-derivatives against human cytomegalovirus and papillomavirus.
| العنوان: | Antiviral potency of lupane and oleanane alkynyl-derivatives against human cytomegalovirus and papillomavirus. |
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| المؤلفون: | Khusnutdinova EF; Ufa Institute of Chemistry of the Ufa Federal Research Centre of the Russian Academy of Sciences, 71 Prospect Oktyabrya, 450054, Ufa, Russian Federation. elmaH@inbox.ru., Petrova AV; Ufa Institute of Chemistry of the Ufa Federal Research Centre of the Russian Academy of Sciences, 71 Prospect Oktyabrya, 450054, Ufa, Russian Federation., Kazakova OB; Ufa Institute of Chemistry of the Ufa Federal Research Centre of the Russian Academy of Sciences, 71 Prospect Oktyabrya, 450054, Ufa, Russian Federation. |
| المصدر: | The Journal of antibiotics [J Antibiot (Tokyo)] 2024 Jan; Vol. 77 (1), pp. 50-56. Date of Electronic Publication: 2023 Nov 07. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0151115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1469 (Electronic) Linking ISSN: 00218820 NLM ISO Abbreviation: J Antibiot (Tokyo) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2009- : London : Nature Publishing Group Original Publication: Tokyo, Japan Antibiotics Research Assn. |
| مواضيع طبية MeSH: | Oleanolic Acid*/pharmacology , Triterpenes*/pharmacology, Humans ; Cytomegalovirus ; Antiviral Agents/pharmacology ; Lupanes |
| مستخلص: | A library of 18 structurally diverse semisynthetic lupane, oleanane, and ursane types triterpenoids, including C19- or C28-(1,2,3-triazolyl)- and aminomethylated derivatives obtained by the «click» reaction with various aromatic and sugar azides or by Mannich reaction with secondary amines, were tested for antiviral activity against HCMV, HSV-1, and HPV-11 types. C28-Triazolyl-derivative with a benzyl substituent of 2,3-indolo-oleanolic acid was the most active against the HCMV virus with EC (© 2023. The Author(s), under exclusive licence to the Japan Antibiotics Research Association.) |
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| المشرفين على المادة: | 0 (oleanane) 6SMK8R7TGJ (Oleanolic Acid) 0 (Triterpenes) 0 (Antiviral Agents) 0 (Lupanes) |
| تواريخ الأحداث: | Date Created: 20231107 Date Completed: 20240108 Latest Revision: 20240416 |
| رمز التحديث: | 20240416 |
| DOI: | 10.1038/s41429-023-00672-5 |
| PMID: | 37935823 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1881-1469 |
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| DOI: | 10.1038/s41429-023-00672-5 |