دورية أكاديمية

Maternal antioxidant micronutrient deficiencies among pre-eclamptic women in Enugu, Nigeria: a cross-sectional analytical study.

التفاصيل البيبلوغرافية
العنوان: Maternal antioxidant micronutrient deficiencies among pre-eclamptic women in Enugu, Nigeria: a cross-sectional analytical study.
المؤلفون: Enebe JT; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine/Teaching Hospital, Enugu, Nigeria., Dim CC; Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Ituku/Ozalla Campus, Enugu state, Nigeria., Omeke AC; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine/Teaching Hospital, Enugu, Nigeria.
المصدر: The Journal of international medical research [J Int Med Res] 2023 Nov; Vol. 51 (11), pp. 3000605231209159.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Sage Publications Country of Publication: England NLM ID: 0346411 Publication Model: Print Cited Medium: Internet ISSN: 1473-2300 (Electronic) Linking ISSN: 03000605 NLM ISO Abbreviation: J Int Med Res Subsets: MEDLINE
أسماء مطبوعة: Publication: Nov. 2012- : London : Sage Publications
Original Publication: Northampton, Eng., Cambridge Medical Publications ltd.
مواضيع طبية MeSH: Trace Elements* , Pre-Eclampsia*/epidemiology , Malnutrition*, Female ; Pregnancy ; Humans ; Antioxidants ; Manganese ; Nigeria/epidemiology ; Cross-Sectional Studies ; Micronutrients
مستخلص: Objectives: To determine the prevalence of antioxidant micronutrient deficiencies in pregnant women with pre-eclampsia and healthy pregnant women, and to assess the relationships between trace element deficiency in pregnancy and the severity of pre-eclampsia in Enugu, Nigeria.
Methods: We performed a secondary analysis of a cross-sectional analytical study of serum concentrations of copper, selenium, zinc, magnesium, and manganese in 81 pregnant women with pre-eclampsia and healthy pregnant women (controls) who were matched for age, gestational age, body mass index, and parity. This study was performed at the University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu. Participants' sera were analyzed with an atomic absorption spectrophotometer.
Results: Trace element deficiencies were common and similar between women with pre-eclampsia and controls. However, women with pre-eclampsia were more likely to be deficient in manganese than controls (odds ratio = 2.28, 95% confidence interval: 1.90-2.75). Among the micronutrients studied, only manganese concentrations were significantly lower in women without severe symptoms of pre-eclampsia than in those with severe symptoms of pre-eclampsia.
Conclusions: Micronutrient deficiency is common in pregnant women with pre-eclampsia and in healthy pregnant women in Enugu, Nigeria. Only manganese deficiency is higher in women with pre-eclampsia than in healthy pregnant women.
Competing Interests: Declaration of conflicting interestThe authors declare that there is no conflict of interest.
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فهرسة مساهمة: Keywords: Pre-eclampsia; copper; deficiency; magnesium; manganese; micro-nutrient; selenium; zinc
المشرفين على المادة: 0 (Antioxidants)
0 (Trace Elements)
42Z2K6ZL8P (Manganese)
0 (Micronutrients)
تواريخ الأحداث: Date Created: 20231108 Date Completed: 20231110 Latest Revision: 20231113
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10637183
DOI: 10.1177/03000605231209159
PMID: 37940611
قاعدة البيانات: MEDLINE
الوصف
تدمد:1473-2300
DOI:10.1177/03000605231209159