دورية أكاديمية
BONEcheck: A digital tool for personalized bone health assessment.
| العنوان: | BONEcheck: A digital tool for personalized bone health assessment. |
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| المؤلفون: | Nguyen DT; School of Biomedical Engineering, University of Technology, Sydney, Australia.; Saigon Precision Medicine Research Center, Ho Chi Minh, Viet Nam., Ho-Le TP; School of Biomedical Engineering, University of Technology, Sydney, Australia.; Faculty of Engineering and Information Technology, Hatinh University, Hatinh, Viet Nam., Pham L; Saigon Precision Medicine Research Center, Ho Chi Minh, Viet Nam., Ho-Van VP; Faculty of Engineering and Information Technology, Hatinh University, Hatinh, Viet Nam., Hoang TD; Faculty of Engineering and Information Technology, Hatinh University, Hatinh, Viet Nam., Tran TS; School of Biomedical Engineering, University of Technology, Sydney, Australia.; Garvan Institute of Medical Research, Sydney, Australia., Frost S; University of Wollongong, Wollongong, Australia., Nguyen TV; School of Biomedical Engineering, University of Technology, Sydney, Australia.; Tam Anh Research Institute, Ho Chi Minh, Viet Nam.; School of Population Health, UNSW Sydney, Australia. |
| المصدر: | Osteoporosis and sarcopenia [Osteoporos Sarcopenia] 2023 Sep; Vol. 9 (3), pp. 79-87. Date of Electronic Publication: 2023 Sep 19. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: The Korean Society of Osteoporosis ; production and hosting by Elsevier B.V Country of Publication: Netherlands NLM ID: 101666399 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-5263 (Electronic) Linking ISSN: 24055255 NLM ISO Abbreviation: Osteoporos Sarcopenia Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Amsterdam] : The Korean Society of Osteoporosis ; production and hosting by Elsevier B.V., [2015]- |
| مستخلص: | Objectives: Osteoporotic fracture is a significant public health burden associated with increased mortality risk and substantial healthcare costs. Accurate and early identification of high-risk individuals and mitigation of their risks is a core part of the treatment and prevention of fractures. Here we introduce a digital tool called 'BONEcheck' for personalized assessment of bone health. Methods: The development of BONEcheck primarily utilized data from the prospective population-based Dubbo Osteoporosis Epidemiology Study and the Danish Nationwide Registry. BONEcheck has 3 modules: input data, risk estimates, and risk context. Input variables include age, gender, prior fracture, fall incidence, bone mineral density (BMD), comorbidities, and genetic variants associated with BMD. Results: Based on the input variables, BONEcheck estimates the probability of any fragility fracture and hip fracture within 5 years, subsequent fracture risk, skeletal age, and time to reach osteoporosis. The probability of fracture is shown in both numeric and human icon array formats. The risk is also contextualized within the framework of treatment and management options on Australian guidelines, with consideration given to the potential fracture risk reduction and survival benefits. Skeletal age was estimated as the sum of chronological age and years of life lost due to a fracture or exposure to risk factors that elevate mortality risk. Conclusions: BONEcheck is an innovative tool that empowers doctors and patients to engage in well-informed discussions and make decisions based on the patient's risk profile. Public access to BONEcheck is available via https://bonecheck.org and in Apple Store (iOS) and Google Play (Android). Competing Interests: Thach Tran, Thao Ho-Le, Dinh Nguyen, Vinh Ho-Van, Tien Hoang and Steve Frost have no competing interests to declare. Dinh Nguyen is supported by a grant from the Medical Research Future Fund (grant number APP1176600). Tuan Van Nguyen has received grants from Australian 10.13039/501100000925National Health and Medical Research Council and 10.13039/100002429Amgen Competitive Grant Program; fees for lectures from 10.13039/100002429Amgen, Bridge Health Care (VN), DKSH Pharma, MSD and VT Health Care (VN); and support from 10.13039/100002429Amgen for attending the annual meeting of APCO and from VT Health Care (VN) for attending the Vietnam Osteoporosis Society Annual Scientific Meeting. Dr. Nguyen is also Chair of the Research Committee for the Australian and New Zealand Bone and Mineral Society, a Senior Advisor for the Vietnam Osteoporosis Society, and an Executive Member of the Asia Pacific Consortium on Osteoporosis. (© 2023 The Korean Society of Osteoporosis. Publishing services by Elsevier B.V.) |
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| فهرسة مساهمة: | Keywords: BONEcheck; BONEcheck guidelines; Osteoporosis prediction; Research translation; Risk assessment tools; Risk prediction |
| تواريخ الأحداث: | Date Created: 20231109 Latest Revision: 20231110 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC10627863 |
| DOI: | 10.1016/j.afos.2023.08.002 |
| PMID: | 37941533 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2405-5263 |
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| DOI: | 10.1016/j.afos.2023.08.002 |