دورية أكاديمية
أعرض في EDS

From premature birth to premature kidney disease: does accelerated aging play a role?

التفاصيل البيبلوغرافية
العنوان: From premature birth to premature kidney disease: does accelerated aging play a role?
المؤلفون: Sanderson KR; Department of Medicine-Nephrology, University of North Carolina, Chapel Hill, NC, USA. keia_sanderson@med.unc.edu., Wekon-Kemeni C; Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.; Division of Pediatric Nephrology, Emory University School of Medicine, and Children's Healthcare of Atlanta, Atlanta, GA, USA., Charlton JR; Department of Pediatrics, Division of Nephrology, University of Virginia, Charlottesville, VA, USA.
المصدر: Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2024 Jul; Vol. 39 (7), pp. 2001-2013. Date of Electronic Publication: 2023 Nov 10.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8708728 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-198X (Electronic) Linking ISSN: 0931041X NLM ISO Abbreviation: Pediatr Nephrol Subsets: MEDLINE
أسماء مطبوعة: Publication: Berlin : Springer International
Original Publication: Berlin : Springer International, c1987-
مواضيع طبية MeSH: Premature Birth*/epidemiology , Aging, Premature*/etiology , Aging, Premature*/physiopathology , Renal Insufficiency, Chronic*/etiology , Renal Insufficiency, Chronic*/physiopathology , Renal Insufficiency, Chronic*/therapy, Humans ; Infant, Newborn ; Aging/physiology ; Pregnancy ; Female ; Risk Factors
مستخلص: As the limits of fetal viability have increased over the past 30 years, there has been a growing body of evidence supporting the idea that chronic disease should be taken into greater consideration in addition to survival after preterm birth. Accumulating evidence also suggests there is early onset of biologic aging after preterm birth. Similarly, chronic kidney disease (CKD) is also associated with a phenotype of advanced biologic age which exceeds chronologic age. Yet, significant knowledge gaps remain regarding the link between premature biologic age after preterm birth and kidney disease. This review summarizes the four broad pillars of aging, the evidence of premature aging following preterm birth, and in the setting of CKD. The aim is to provide additional plausible biologic mechanisms to explore the link between preterm birth and CKD. There is a need for more research to further elucidate the biologic mechanisms of the premature aging paradigm and kidney disease after preterm birth. Given the emerging research on therapies for premature aging, this paradigm could create pathways for prevention of advanced CKD.
(© 2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)
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معلومات مُعتمدة: R21 DK134104 United States DK NIDDK NIH HHS; R56 DK110622 United States DK NIDDK NIH HHS; R41 DK129138 United States DK NIDDK NIH HHS; K23DK131289 United States DK NIDDK NIH HHS; K23 DK131289 United States DK NIDDK NIH HHS; L40 DK130155 United States DK NIDDK NIH HHS; R21DK134104-01 United States DK NIDDK NIH HHS; P50 DK096373 United States DK NIDDK NIH HHS; L40DK130155 United States DK NIDDK NIH HHS; K23DK131289 United States DK NIDDK NIH HHS; L40DK130155 United States DK NIDDK NIH HHS; R21DK134104-01 United States DK NIDDK NIH HHS
فهرسة مساهمة: Keywords: Acute kidney injury; Chronic kidney disease; ELGANS; Infants; Neonates; Premature aging; Very low birth weight
تواريخ الأحداث: Date Created: 20231110 Date Completed: 20240603 Latest Revision: 20240702
رمز التحديث: 20240702
مُعرف محوري في PubMed: PMC11082067
DOI: 10.1007/s00467-023-06208-1
PMID: 37947901
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-198X
DOI:10.1007/s00467-023-06208-1