دورية أكاديمية
Lactiplantibacillus plantarum as a promising adjuvant for neurological disorders therapy through the brain-gut axis and related action pathways.
| العنوان: | Lactiplantibacillus plantarum as a promising adjuvant for neurological disorders therapy through the brain-gut axis and related action pathways. |
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| المؤلفون: | Duarte Luiz J; Department of Health Sciences, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil., Manassi C; Federal Institute of Science and Technology of Paraná (IFPR), Paranavaí, Brazil., Magnani M; Laboratory of Microbial Processes in Foods, Federal University of Paraiba, João Pessoa, PB, Brazil., Cruz AGD; Science and Technology of Rio de Janeiro (IFRJ), Department of Food, Federal Institute of Education, Rio de Janeiro, Brazil., Pimentel TC; Federal Institute of Science and Technology of Paraná (IFPR), Paranavaí, Brazil., Verruck S; Department of Health Sciences, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil.; Graduate Program of Food Science, Department of Food Science and Technology, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil. |
| المصدر: | Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2023 Nov 11, pp. 1-13. Date of Electronic Publication: 2023 Nov 11. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 8914818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-7852 (Electronic) Linking ISSN: 10408398 NLM ISO Abbreviation: Crit Rev Food Sci Nutr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : Taylor & Francis Group Original Publication: Boca Raton, Fla. : CRC Press, c1980- |
| مستخلص: | Dysbiosis in neurological disorders has highlighted the gut-microbiota-brain axis and psychobiotics and their ability to act on the brain-gut axis. Studying and discovering new approaches in therapies for neuropsychiatric disorders are strategies that have been discussed and put into practice. Lactiplantibacillus plantarum is a lactic acid bacteria species with an extensive history of safe use whose action as a psychobiotic has been successfully explored. This review describes and discusses the mechanisms of action of L. plantarum and its potential for the prevention and treatment of neurological disorders. Randomized and controlled trials in humans or animals and using supplements based on different strains of L. plantarum were selected. The psychobiotic effect of L. plantarum has been shown, mainly through its action on the Hypothalamic-Pituitary-Adrenal (HPA) axis and regulation of levels of pro-inflammatory cytokines. Furthermore, it could protect the integrity of the intestinal barrier and decrease inflammation, alleviating a series of symptoms of neurological diseases. The results showed improvements in cognitive function, memory, anxiety, hyperactivity, Attention Deficit Hyperactivity Disorder (ADHD), sleep quality, and growth stimulation of beneficial species of bacteria in the gut. Larger and deeper studies are needed to use psychobiotics to prevent and treat neurological disorders. |
| فهرسة مساهمة: | Keywords: Lactobacillus plantarum; Stress; anxiety; depression; major depressive disorder; microbiota |
| تواريخ الأحداث: | Date Created: 20231111 Latest Revision: 20231111 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/10408398.2023.2280247 |
| PMID: | 37950651 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1549-7852 |
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| DOI: | 10.1080/10408398.2023.2280247 |