دورية أكاديمية
Toxicities of Legacy and Current-Use PFAS in an Anuran: Do Larval Exposures Influence Responses to a Terrestrial Pathogen Challenge?
| العنوان: | Toxicities of Legacy and Current-Use PFAS in an Anuran: Do Larval Exposures Influence Responses to a Terrestrial Pathogen Challenge? |
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| المؤلفون: | Barragan EM; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States., Hoskins TD; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States., Allmon EB; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States., McQuigg JL; Department of Biology, Drew University, Madison, New Jersey 07940, United States., Hamilton MT; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States., Christian EN; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States., Coogan GSM; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States., Searle CL; Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, United States., Choi YJ; Agronomy, Purdue University, West Lafayette, Indiana 47907, United States., Lee LS; Agronomy, Purdue University, West Lafayette, Indiana 47907, United States., Hoverman JT; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States., Sepúlveda MS; Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States.; Sustainability Research Center and PhD in Conservation Medicine, Life Sciences Faculty, Universidad Andres Bello, Santiago 7550196, Chile. |
| المصدر: | Environmental science & technology [Environ Sci Technol] 2023 Dec 05; Vol. 57 (48), pp. 19180-19189. Date of Electronic Publication: 2023 Nov 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0213155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5851 (Electronic) Linking ISSN: 0013936X NLM ISO Abbreviation: Environ Sci Technol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Washington DC : American Chemical Society Original Publication: Easton, Pa. : American Chemical Society, c1967- |
| مواضيع طبية MeSH: | Fluorocarbons*/toxicity , Alkanesulfonic Acids*/toxicity, Animals ; Larva/microbiology ; Anura/microbiology |
| مستخلص: | Legacy polyfluoroalkyl substances (PFAS) [perfluorooctanesulfonate (PFOS) and perfluorooctanoic acid (PFOA)] are being replaced by various other fluorinated compounds, such as hexafluoropropylene oxide dimer acid (GenX). These alternatives are thought to be less bioaccumulative and, therefore, less toxic than legacy PFAS. Contaminant exposures occur concurrently with exposure to natural stressors, including the fungal pathogen Batrachocytrium dendrobatidis ( Bd ). Despite evidence that other pollutants can increase the adverse effects of Bd on anurans, no studies have examined the interactive effects of Bd and PFAS. This study tested the growth and developmental effects of PFOS, PFOA, and GenX on gray treefrog ( Hyla versicolor ) tadpoles, followed by a Bd challenge after metamorphosis. Despite PFAS exposure only occurring during the larval stage, carry-over effects on growth were observed post metamorphosis. Further, PFAS interacted with Bd exposure to influence growth; Bd -exposed animals had significantly shorter SVL [snout-vent length (mm)] with significantly increased body condition, among other time-dependent effects. Our data suggest that larval exposure to PFAS can continue to impact growth in the juvenile stage after exposure has ended. Contrary to predictions, GenX affected terrestrial performance more consistently than its legacy congener, PFOA. Given the role of Bd in amphibian declines, further investigation of interactions of PFAS with Bd and other environmentally relevant pathogens is warranted. |
| فهرسة مساهمة: | Keywords: amphibian; frog; fungi; toxicity; wildlife |
| المشرفين على المادة: | 947VD76D3L (perfluorooctanoic acid) 0 (Fluorocarbons) 9H2MAI21CL (perfluorooctane sulfonic acid) 0 (Alkanesulfonic Acids) |
| تواريخ الأحداث: | Date Created: 20231114 Date Completed: 20231207 Latest Revision: 20231207 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1021/acs.est.3c03191 |
| PMID: | 37962853 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 1520-5851 |
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| DOI: | 10.1021/acs.est.3c03191 |