دورية أكاديمية
People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training.
| العنوان: | People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training. |
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| المؤلفون: | Srisawat K; Research Institute for Sport, & Exercise Sciences, Liverpool, UK., Stead CA; Research Institute for Sport, & Exercise Sciences, Liverpool, UK., Hesketh K; Research Institute for Sport, & Exercise Sciences, Liverpool, UK., Pogson M; Research Institute for Sport, & Exercise Sciences, Liverpool, UK., Strauss JA; Research Institute for Sport, & Exercise Sciences, Liverpool, UK., Cocks M; Research Institute for Sport, & Exercise Sciences, Liverpool, UK., Siekmann I; Department of Applied Mathematics, Liverpool John Moores University, Liverpool, UK., Phillips SM; Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada., Lisboa PJ; Department of Applied Mathematics, Liverpool John Moores University, Liverpool, UK., Shepherd S; Research Institute for Sport, & Exercise Sciences, Liverpool, UK., Burniston JG; Research Institute for Sport, & Exercise Sciences, Liverpool, UK. |
| المصدر: | Proteomics [Proteomics] 2024 Jul; Vol. 24 (14), pp. e2300395. Date of Electronic Publication: 2023 Nov 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101092707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-9861 (Electronic) Linking ISSN: 16159853 NLM ISO Abbreviation: Proteomics Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Weinheim, Germany : Wiley-VCH, |
| مواضيع طبية MeSH: | Obesity*/metabolism , Proteostasis* , Muscle, Skeletal*/metabolism , Muscle Proteins*/metabolism , Exercise*/physiology, Humans ; Male ; Adult ; Proteomics/methods ; High-Intensity Interval Training/methods ; Pilot Projects ; Middle Aged ; Insulin Resistance |
| مستخلص: | This pilot experiment examines if a loss in muscle proteostasis occurs in people with obesity and whether endurance exercise positively influences either the abundance profile or turnover rate of proteins in this population. Men with (n = 3) or without (n = 4) obesity were recruited and underwent a 14-d measurement protocol of daily deuterium oxide (D (© 2023 The Authors. PROTEOMICS published by Wiley‐VCH GmbH.) |
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| معلومات مُعتمدة: | Royal Thai Government |
| فهرسة مساهمة: | Keywords: biosynthetic labelling; deuterium oxide; fractional synthesis rate; heat shock proteins; heavy water; muscle protein synthesis; protein turnover; proteomics; skeletal muscle; ubiquitin proteasome system |
| المشرفين على المادة: | 0 (Muscle Proteins) |
| تواريخ الأحداث: | Date Created: 20231114 Date Completed: 20240712 Latest Revision: 20240712 |
| رمز التحديث: | 20240712 |
| DOI: | 10.1002/pmic.202300395 |
| PMID: | 37963832 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1615-9861 |
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| DOI: | 10.1002/pmic.202300395 |