دورية أكاديمية

The Need to Rethink Harm Reduction for People Using Drugs Alone to Reduce Overdose Fatalities.

التفاصيل البيبلوغرافية
العنوان: The Need to Rethink Harm Reduction for People Using Drugs Alone to Reduce Overdose Fatalities.
المؤلفون: Deo VS; Jack, Joseph and Morton Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, Ohio, USA., Bhullar MK; Cuyahoga County Medical Examiner's Office, Cleveland, Ohio, USA., Gilson TP; Cuyahoga County Medical Examiner's Office, Cleveland, Ohio, USA., Flannery DJ; Jack, Joseph and Morton Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, Ohio, USA., Fulton SE; Jack, Joseph and Morton Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
المصدر: Substance use & misuse [Subst Use Misuse] 2024; Vol. 59 (3), pp. 450-458. Date of Electronic Publication: 2024 Jan 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9602153 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2491 (Electronic) Linking ISSN: 10826084 NLM ISO Abbreviation: Subst Use Misuse Subsets: MEDLINE
أسماء مطبوعة: Publication: London : Informa Healthcare
Original Publication: Monticello, NY : Dekker, 1996-
مواضيع طبية MeSH: Drug Overdose*/epidemiology , Substance-Related Disorders*, Adult ; Humans ; Fentanyl ; Harm Reduction ; Naloxone/therapeutic use ; Analgesics, Opioid
مستخلص: Background : During the ongoing opioid epidemic, Cuyahoga County (second largest in Ohio) reported overdose mortality rates (54/per 100,000) higher than the national average. Prior research demonstrates that people who use drugs often use alone but there is minimal research on people who died of overdose while using alone. The objective of this study is to examine sociodemographic, toxicologic, and injury characteristics, and emergency medical response to overdose decedents who died using drugs alone. Method : Data from the Cuyahoga County Medical Examiner's Office (2016-2020, N  = 2944) on unintentional overdose deaths in adults was tabulated including socio-demographic, toxicologic, and injury-related information. Decedents using drugs alone were identified and compared to those not using alone via Chi-square and Fisher's exact tests. We further fit a multivariate logistic regression model to evaluate socio-demographic, toxicologic, and injury-related factors associated with increased odds of using alone. All results are reported with 95% confidence intervals. Result : Among decedents, 75% ( n  = 2205) were using drugs alone. Decedents using alone were more likely to be using drugs at home ( p =  0.001) or be found dead at the scene ( p  < 0.001) and less likely to receive naloxone ( p  < 0.001) have other person/bystander, not using, present ( p =  0.002). Using drugs at home (aOR = 1.61[1.19-2.20]) was associated with higher odds of using alone; and being married (aOR = 0.57[0.38-0.86]), having history of illicit drug use (aOR = 0.25[0.08-0.81]) and other person present, who was not using (aOR = 0.58[0.42-0.79]) were associated with lower odds of using alone. Conclusion : New harm reduction approaches targeting people using drugs alone are needed to reduce overdose deaths.
معلومات مُعتمدة: NO. 5-NU17CE925005-02-00 United States CC CDC HHS
فهرسة مساهمة: Keywords: Unintentional overdose death; analogs; harm reduction; illicitly manufactured fentanyl; using alone
المشرفين على المادة: UF599785JZ (Fentanyl)
36B82AMQ7N (Naloxone)
0 (Analgesics, Opioid)
تواريخ الأحداث: Date Created: 20231115 Date Completed: 20240126 Latest Revision: 20240131
رمز التحديث: 20240131
DOI: 10.1080/10826084.2023.2280534
PMID: 37964569
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-2491
DOI:10.1080/10826084.2023.2280534