دورية أكاديمية
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Effects of overground gait training assisted by a wearable exoskeleton in patients with Parkinson's disease.

التفاصيل البيبلوغرافية
العنوان: Effects of overground gait training assisted by a wearable exoskeleton in patients with Parkinson's disease.
المؤلفون: Otlet V; Institute of Mechanics, Materials, and Civil Engineering, UCLouvain, Louvain-la-Neuve, Belgium. virginie.otlet@uclouvain.be.; Institute of Neuroscience, UCLouvain, Brussels, Belgium. virginie.otlet@uclouvain.be.; Louvain Bionics, UCLouvain, Louvain-la-Neuve, Belgium. virginie.otlet@uclouvain.be., Vandamme C; Institute of Neuroscience, UCLouvain, Brussels, Belgium.; Louvain Bionics, UCLouvain, Louvain-la-Neuve, Belgium.; Institute of Information and Communication Technologies, Electronics and Applied Mathematics, UCLouvain, Louvain-la-Neuve, Belgium., Warlop T; Institute of Neuroscience, UCLouvain, Brussels, Belgium.; Louvain Bionics, UCLouvain, Louvain-la-Neuve, Belgium.; Service de Neurologie, Centre Hospitalier de Wallonie Picarde, Tournai, Belgium.; Service de Neurologie (Pathologie du Mouvement), Centre Hospitalier Universitaire de Lille, Lille, France., Crevecoeur F; Institute of Neuroscience, UCLouvain, Brussels, Belgium.; Louvain Bionics, UCLouvain, Louvain-la-Neuve, Belgium.; Institute of Information and Communication Technologies, Electronics and Applied Mathematics, UCLouvain, Louvain-la-Neuve, Belgium., Ronsse R; Institute of Mechanics, Materials, and Civil Engineering, UCLouvain, Louvain-la-Neuve, Belgium.; Institute of Neuroscience, UCLouvain, Brussels, Belgium.; Louvain Bionics, UCLouvain, Louvain-la-Neuve, Belgium.
المصدر: Journal of neuroengineering and rehabilitation [J Neuroeng Rehabil] 2023 Nov 16; Vol. 20 (1), pp. 156. Date of Electronic Publication: 2023 Nov 16.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101232233 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-0003 (Electronic) Linking ISSN: 17430003 NLM ISO Abbreviation: J Neuroeng Rehabil Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, 2004-
مواضيع طبية MeSH: Parkinson Disease*/rehabilitation , Exoskeleton Device* , Robotics*, Humans ; Gait ; Exercise Therapy ; Walking
مستخلص: Background: In the recent past, wearable devices have been used for gait rehabilitation in patients with Parkinson's disease. The objective of this paper is to analyze the outcome of a wearable hip orthosis whose assistance adapts in real time to the patient's gait kinematics via adaptive oscillators. In particular, this study focuses on a metric characterizing natural gait variability, i.e., the level of long-range autocorrelations (LRA) in series of stride durations.
Methods: Eight patients with Parkinson's disease (Hoehn and Yahr stages 1[Formula: see text]2.5) performed overground gait training three times per week for four consecutive weeks, assisted by a wearable hip orthosis. Gait was assessed based on performance metrics such as the hip range of motion, speed, stride length and duration, and the level of LRA in inter-stride time series assessed using the Adaptive Fractal Analysis. These metrics were measured before, directly after, and 1 month after training.
Results: After training, patients increased their hip range of motion, their gait speed and stride length, and decreased their stride duration. These improvements were maintained 1 month after training. Regarding long-range autocorrelations, the population's behavior was standardized towards a metric closer to the one of healthy individuals after training, but with no retention after 1 month.
Conclusion: This study showed that an overground gait training with adaptive robotic assistance has the potential to improve key gait metrics that are typically affected by Parkinson's disease and that lead to higher prevalence of fall.
Trial Registration: ClinicalTrials.gov Identifer NCT04314973. Registered on 11 April 2020.
(© 2023. The Author(s).)
References: Disabil Rehabil Assist Technol. 2011;6(1):77-85. (PMID: 20666620)
J Biomech. 2018 Jul 25;76:144-151. (PMID: 29914740)
J Mot Behav. 1983 Dec;15(4):302-30. (PMID: 15151864)
Medicine (Baltimore). 2021 Feb 5;100(5):e24348. (PMID: 33592882)
Mov Disord. 2015 Mar;30(3):359-67. (PMID: 25546558)
J Neurol Phys Ther. 2019 Jan;43(1):56-62. (PMID: 30531387)
Ann Phys Rehabil Med. 2019 Sep;62(5):303-312. (PMID: 31377382)
Drugs Aging. 2019 Feb;36(2):103-113. (PMID: 30556112)
J Neurophysiol. 2023 Aug 1;130(2):417-426. (PMID: 37465888)
Med Biol Eng Comput. 2011 Oct;49(10):1173-85. (PMID: 21881902)
CMAJ. 2016 Nov 1;188(16):1157-1165. (PMID: 27221269)
PLoS Comput Biol. 2010 Jul 15;6(7):e1000856. (PMID: 20657664)
NeuroRehabilitation. 2014;35(4):779-88. (PMID: 25318782)
Mov Disord. 2017 Aug;32(8):1147-1154. (PMID: 28605054)
Funct Neurol. 2016 Jul-Sep;31(3):163-70. (PMID: 27678210)
Chaos. 2013 Dec;23(4):043109. (PMID: 24387548)
Hum Mov Sci. 2017 Oct;55:31-42. (PMID: 28750259)
Front Physiol. 2018 Feb 06;9:68. (PMID: 29467673)
Chaos. 2009 Jun;19(2):026113. (PMID: 19566273)
NeuroRehabilitation. 2013;33(2):323-8. (PMID: 23949054)
Gait Posture. 2017 Jan;51:64-69. (PMID: 27710836)
Neurorehabil Neural Repair. 2012 Nov-Dec;26(9):1027-34. (PMID: 22623206)
Parkinsonism Relat Disord. 2012 Sep;18(8):990-3. (PMID: 22673035)
J Appl Physiol (1985). 1996 May;80(5):1448-57. (PMID: 8727526)
Ann Biomed Eng. 2014 Apr;42(4):742-50. (PMID: 24366525)
Parkinsonism Relat Disord. 2018 Dec;57:1-8. (PMID: 30041848)
Phys Ther. 2022 Apr 1;102(4):. (PMID: 34963139)
Intern Med. 2022 Sep 1;61(17):2573-2580. (PMID: 35135928)
J Neurol. 2001 Nov;248(11):950-8. (PMID: 11757958)
J Neurol Neurosurg Psychiatry. 2012 Oct;83(10):979-85. (PMID: 22752693)
Parkinsonism Relat Disord. 2013 Jun;19(6):605-10. (PMID: 23490463)
J Rehabil Med. 2016 Nov 11;48(10):865-871. (PMID: 27735982)
Gait Posture. 2005 Feb;21(2):178-85. (PMID: 15639397)
BMC Neurol. 2013 May 24;13:50. (PMID: 23706025)
J Neurol Sci. 2015 Aug 15;355(1-2):75-8. (PMID: 26048047)
J Neuroeng Rehabil. 2010 Oct 14;7:51. (PMID: 20946640)
Crit Rev Biomed Eng. 2012;40(6):485-500. (PMID: 23356693)
Biometrics. 1997 Sep;53(3):983-97. (PMID: 9333350)
Eur J Phys Rehabil Med. 2021 Jun;57(3):472-477. (PMID: 33826278)
Parkinsons Dis. 2019 Sep 22;2019:5679187. (PMID: 31662843)
Gait Posture. 2020 Mar;77:195-200. (PMID: 32058283)
Sensors (Basel). 2019 May 13;19(9):. (PMID: 31086054)
Eur J Phys Rehabil Med. 2022 Oct;58(5):723-737. (PMID: 35708047)
IEEE Trans Neural Syst Rehabil Eng. 2023 Feb 14;PP:. (PMID: 37022872)
PLoS One. 2016 Sep 01;11(9):e0161689. (PMID: 27583564)
J Neuroeng Rehabil. 2011 Feb 24;8:12. (PMID: 21345241)
Gait Posture. 2022 May;94:9-14. (PMID: 35189574)
Neurorehabil Neural Repair. 2012 May;26(4):353-61. (PMID: 22258155)
J Neurol. 2013 Jan;260(1):296-8. (PMID: 23070468)
IEEE Trans Biomed Eng. 2011 Apr;58(4):1001-12. (PMID: 20977981)
Front Physiol. 2012 Sep 28;3:371. (PMID: 23060804)
J Neuroeng Rehabil. 2017 Apr 14;14(1):29. (PMID: 28410594)
معلومات مُعتمدة: PDR T.0200.19: PaDAWAn project Fonds De La Recherche Scientifique - FNRS
فهرسة مساهمة: Keywords: Long-range autocorrelations; Parkinson’s disease; Walking assistance; Wearable device
سلسلة جزيئية: ClinicalTrials.gov NCT04314973
تواريخ الأحداث: Date Created: 20231117 Date Completed: 20231127 Latest Revision: 20240118
رمز التحديث: 20240118
مُعرف محوري في PubMed: PMC10655429
DOI: 10.1186/s12984-023-01280-y
PMID: 37974229
قاعدة البيانات: MEDLINE
الوصف
تدمد:1743-0003
DOI:10.1186/s12984-023-01280-y