دورية أكاديمية
أعرض في EDS

Medication error and associated factors among adults admitted to emergency ward at the university of Gondar comprehensive specialized hospital, North-West Ethiopia: a cross-sectional study, 2022.

التفاصيل البيبلوغرافية
العنوان: Medication error and associated factors among adults admitted to emergency ward at the university of Gondar comprehensive specialized hospital, North-West Ethiopia: a cross-sectional study, 2022.
المؤلفون: Gebremariam SN; Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia. saronnaji@gmail.com., Sema FD; Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia., Jara AG; Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia., Mekonen BT; Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia., Mekonnen GA; Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
المصدر: Journal of pharmaceutical policy and practice [J Pharm Policy Pract] 2023 Nov 17; Vol. 16 (1), pp. 148. Date of Electronic Publication: 2023 Nov 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Informa UK Limited Country of Publication: England NLM ID: 101627192 Publication Model: Electronic Cited Medium: Print ISSN: 2052-3211 (Print) Linking ISSN: 20523211 NLM ISO Abbreviation: J Pharm Policy Pract Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2024- : London : Informa UK Limited
Original Publication: London : BioMed Central, 2013-
مستخلص: Background: Medication errors are the most common cause of preventable adverse drug events at the emergency ward.
Objectives: This study assessed medication errors and associated factors among adult patients admitted to the emergency ward at the University of Gondar Comprehensive Specialized Hospital, North-West Ethiopia.
Methods: A cross-sectional study was conducted from June 1, 2022, to August 30, 2022. Data were entered into EpiData Manager 4.6.0.0 for clearing and exported to SPSS version 24 for analysis. Descriptive statistics such as frequencies, medians with an interquartile range and inferential statistics like binary logistic regression were used for data analysis. The level of significance was declared at a p value less than 0.05 with a 95% confidence interval.
Results: From 422 study participants, medication errors were found in three-fourths (74.4%) of study participants. The most frequent type of medication error was omitted dose (26.27%). From a total of 491 medication errors, 97.75% were not prevented before reaching patients. More than one-third (38.9%) of medication errors had potentially moderate harmful outcomes. More than half (55.15%) of possible causes of medication errors committed by staff are due to behavioral factors. Physicians accepted 99.16% and nurses accepted 98.71% of clinical pharmacist intervention. Hospital stay ≥ 6 days (AOR: 3.00 95% CI 1.65-5.45, p < 0.001), polypharmacy (AOR: 5.47, 95% CI 2.77-10.81 p < 0.001), and Charlson comorbidity index ≥ 3 (AOR: 1.94, 95% CI (1.02-3.68), p < 0.04) significantly associated with medication error.
Conclusions: About three-fourths of adult patients admitted to the emergency ward experienced medication errors. A considerable amount of medication errors were potentially moderately harmful. Most medication errors were due to behavioral factors. Most clinical pharmacists' interventions were accepted by physicians and nurses. Patients who stayed longer at the emergency ward, had a Charlson comorbidity index value of ≥ 3, and were on polypharmacy were at high risk of medication error. The hospital should strive to reduce medication errors at the emergency ward.
(© 2023. The Author(s).)
References: BMC Health Serv Res. 2017 Sep 4;17(1):621. (PMID: 28870178)
J Emerg Med. 2018 Apr;54(4):402-409. (PMID: 29366616)
PLOS Glob Public Health. 2022 Dec 13;2(12):e0001085. (PMID: 36962880)
J Am Pharm Assoc (2003). 2015 Mar-Apr;55(2):e264-74; quiz e275-6. (PMID: 25749270)
Cureus. 2021 Dec 12;13(12):e20374. (PMID: 35036207)
BMC Health Serv Res. 2018 Apr 10;18(1):259. (PMID: 29631587)
BMC Health Serv Res. 2022 Mar 3;22(1):292. (PMID: 35241078)
Environ Health Prev Med. 2019 Mar 9;24(1):18. (PMID: 30851726)
Drug Healthc Patient Saf. 2021 Nov 08;13:221-228. (PMID: 34795534)
Drugs Real World Outcomes. 2018 Mar;5(1):1-24. (PMID: 29138993)
BMJ. 2005 Jul 30;331(7511):293-4. (PMID: 16052026)
Medicine (Baltimore). 2020 Aug 21;99(34):e21650. (PMID: 32846776)
BMC Nurs. 2020 Jan 13;19:4. (PMID: 31956293)
Am J Health Syst Pharm. 2018 Oct 1;75(19):1493-1517. (PMID: 30257844)
Pharmacy (Basel). 2022 Aug 31;10(5):. (PMID: 36136841)
Cancer Manag Res. 2021 May 10;13:3739-3748. (PMID: 34007209)
Stud Health Technol Inform. 2016;225:979-80. (PMID: 27332441)
BMC Health Serv Res. 2021 Aug 23;21(1):859. (PMID: 34425816)
Indian J Crit Care Med. 2020 Apr;24(4):252-257. (PMID: 32565635)
Eur J Hosp Pharm. 2021 Nov;28(Suppl 2):e56-e61. (PMID: 32576572)
Int J Clin Pharm. 2020 Feb;42(1):141-149. (PMID: 32026348)
BMC Geriatr. 2020 Jan 13;20(1):13. (PMID: 31931723)
Front Public Health. 2020 Nov 19;8:531038. (PMID: 33330300)
Int J Clin Pharm. 2017 Jun;39(3):542-550. (PMID: 28374341)
Clin Interv Aging. 2019 Mar 21;14:587-600. (PMID: 30962679)
J Physiother. 2016 Jul;62(3):171. (PMID: 27298055)
Drug Healthc Patient Saf. 2020 Jan 10;12:1-14. (PMID: 32021477)
BMJ Open. 2017 Jul 26;7(7):e013658. (PMID: 28751484)
Pharmacoepidemiol Drug Saf. 2017 May;26(5):481-497. (PMID: 28295821)
BMC Health Serv Res. 2019 Sep 6;19(1):644. (PMID: 31492182)
Nephron. 1976;16(1):31-41. (PMID: 1244564)
Saudi Pharm J. 2014 Apr;22(2):101-6. (PMID: 24648820)
J Investig Med. 2021 Jan;69(1):75-85. (PMID: 33051358)
Br J Clin Pharmacol. 2009 Jun;67(6):599-604. (PMID: 19594526)
Lancet Respir Med. 2019 Jan;7(1):13-15. (PMID: 30553847)
Pediatric Health Med Ther. 2017 May 12;8:57-64. (PMID: 29388628)
BMJ Open. 2020 Dec 17;10(12):e037997. (PMID: 33334828)
Lancet Oncol. 2018 Apr;19(4):e191-e199. (PMID: 29611527)
Ann Fam Med. 2009 Jul-Aug;7(4):357-63. (PMID: 19597174)
BMC Health Serv Res. 2020 Jan 22;20(1):56. (PMID: 31969138)
Pharmacy (Basel). 2019 Dec 20;8(1):. (PMID: 31861770)
Drugs Real World Outcomes. 2017 Jun;4(2):97-107. (PMID: 28527149)
Iran J Pharm Res. 2013 Fall;12(4):937-42. (PMID: 24523775)
Sci Rep. 2022 Oct 12;12(1):17107. (PMID: 36224350)
Lancet. 2017 Apr 29;389(10080):1680-1681. (PMID: 28463129)
فهرسة مساهمة: Keywords: Adverse drug event; Medication error; Patient safety
تواريخ الأحداث: Date Created: 20231118 Latest Revision: 20231124
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10655288
DOI: 10.1186/s40545-023-00616-2
PMID: 37978391
قاعدة البيانات: MEDLINE
الوصف
تدمد:2052-3211
DOI:10.1186/s40545-023-00616-2