دورية أكاديمية

Is there still yaws in Nigeria? Active case search in endemic areas of southern Nigeria.

التفاصيل البيبلوغرافية
العنوان: Is there still yaws in Nigeria? Active case search in endemic areas of southern Nigeria.
المؤلفون: Ekeke N; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Iyama FS; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Chukwu JN; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Asiedu K; Department of Control of Neglected Tropical Diseases, WHO, Geneva, Switzerland., Marks M; Department of Clinical Research, London School of Hygiene and Tropical Medicine (LSHTM), London, England., Omotowo B; Institute of Public Health, University of Nigeria, Nsukka, Nigeria., Agwu-Umahi O; Institute of Public Health, University of Nigeria, Nsukka, Nigeria., Nvene VO; Institute of Public Health, University of Nigeria, Nsukka, Nigeria., Paul S; Neglected Tropical Diseases Division, Federal Ministry of Health, Abuja, Nigeria., Nwafor CC; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Meka AO; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Eze CC; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Ezeakile OE; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Njoku MI; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria., Murphy-Okpala NN; German Leprosy and Tuberculosis Relief Association (GLRA), Enugu, Nigeria.
المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Nov 20; Vol. 17 (11), pp. e0011753. Date of Electronic Publication: 2023 Nov 20 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Treponema pallidum* , Yaws*/diagnosis , Yaws*/epidemiology , Yaws*/microbiology, Child ; Humans ; Nigeria/epidemiology ; Treponema
مستخلص: Background: Yaws is a disease caused by the bacteria Treponema pallidum subspecies pertenue, which is most commonly seen among children below 15 years. In the twentieth century yaws was endemic in Nigeria but eradication strategies markedly reduced the disease burden. Currently there is minimal data on the ongoing transmission of yaws in Nigeria, despite reports of confirmed yaws cases in neighbouring West African countries.
Methods: We conducted both community and school-based active yaws case search among school-aged children in southeast Nigeria. Children were screened by trained community volunteers. Suspected yaws cases were clinically reviewed and tested using rapid diagnostic serological tests.
Results: Between February and May 2021, up to 28 trained community volunteers screened a total of 105,015 school children for yaws. Overall, 7,706 children with various skin lesions were identified. Eight (8) suspected cases of yaws were reported, reviewed and screened, but none was confirmed using rapid diagnostic tests. The four most common skin conditions identified were scabies (39%), papular urticaria (29%), tinea corporis (14%) and tinea capitis (12%).
Conclusions: No case of yaws was confirmed in this large population of children in south-east Nigeria. Continuous community awareness and yaws case finding activities have been recommended across Nigeria.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2023 Ekeke et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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معلومات مُعتمدة: 001 International WHO_ World Health Organization
SCR Organism: Treponema pallidum subsp. pertenue
تواريخ الأحداث: Date Created: 20231120 Date Completed: 20231206 Latest Revision: 20231214
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10695364
DOI: 10.1371/journal.pntd.0011753
PMID: 37983269
قاعدة البيانات: MEDLINE
الوصف
تدمد:1935-2735
DOI:10.1371/journal.pntd.0011753