دورية أكاديمية
Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
العنوان: | Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings. |
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المؤلفون: | Vaz LM; Chemical Process Engineering and Forest Products Research Centre, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal., Branco R; Centre for Mechanical Engineering, Materials and Processes, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal., Morais PV; Centre for Mechanical Engineering, Materials and Processes, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal., Guiomar AJ; Chemical Process Engineering and Forest Products Research Centre, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal. |
المصدر: | Membranes [Membranes (Basel)] 2023 Nov 08; Vol. 13 (11). Date of Electronic Publication: 2023 Nov 08. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101577807 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0375 (Print) Linking ISSN: 20770375 NLM ISO Abbreviation: Membranes (Basel) Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI Publishing |
مستخلص: | Wound infection is a common complication of chronic wounds. It can impair healing, which may not occur without external help. Antimicrobial dressings (AMDs) are a type of external help to infected chronic wounds. In this study, highly porous membranes made of only chitosan and containing the antiseptic polyhexanide (poly(hexamethylene biguanide); PHMB) were prepared by cryogelation, aiming to be used in AMDs. These membranes exhibited a water swelling capacity of 748%, a water drop penetration time of 11 s in a dry membrane and a water vapor transmission rate of 34,400 g H |
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معلومات مُعتمدة: | PTDC/CTMBIO73640/2014 Fundação para a Ciência e Tecnologia; ERA-MIN 2 REVIVING ERA-MIN-2019_67 Fundação para a Ciência e Tecnologia; UIDB/00102/2020 Fundação para a Ciência e Tecnologia; UIDP/00102/2020 Fundação para a Ciência e Tecnologia; UIDB/00285/2020 Fundação para a Ciência e Tecnologia; UIDB/04564/2020 Fundação para a Ciência e Tecnologia; BIORECOVER (grant agreement no. 821096) European Union's Horizon 2020 research and innovation programme |
فهرسة مساهمة: | Keywords: PHMB; antimicrobial; chitosan; controlled drug release; drug delivery; membrane; poly(hexamethylene biguanide); polyhexamethylene biguanide; polyhexanide; wound dressing |
تواريخ الأحداث: | Date Created: 20231124 Latest Revision: 20231127 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC10673555 |
DOI: | 10.3390/membranes13110877 |
PMID: | 37999363 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2077-0375 |
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DOI: | 10.3390/membranes13110877 |