التفاصيل البيبلوغرافية
| العنوان: |
The Application of Organoids in the Research of Skeletal Diseases: Current Status and Prospects. |
| المؤلفون: |
Wu J; The Third School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China., Yang Z; The Third School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China., Yang B; The Third School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China., Huang H; Osteoporosis Research Institute, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. |
| المصدر: |
Studies in health technology and informatics [Stud Health Technol Inform] 2023 Nov 23; Vol. 308, pp. 597-604. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9214582 Publication Model: Print Cited Medium: Internet ISSN: 1879-8365 (Electronic) Linking ISSN: 09269630 NLM ISO Abbreviation: Stud Health Technol Inform |
| أسماء مطبوعة: |
Original Publication: Amsterdam ; Washington, DC : IOS Press, 1991- |
| مواضيع طبية MeSH: |
Organoids* , Tissue Engineering*, Stem Cells ; Engineering |
| مستخلص: |
Organoids, which are clumps of cells formed after in vitro 3D culture utilizing autologous tissue and stem cells, possess the 3D structure and corresponding functional and genetic features of the original tissue and organ. This model has immense potential in modeling the ontogeny of specific organismal organs, as well as in drug screening and studying molecular mechanisms. The newly developed concept of bone organoids, a special type of complex hard tissues that can be created in vitro using tissue engineering 3D culture technology, mimics the complex biological functions of bone tissue in vivo. These bone organoids are highly useful in elucidating the regulatory mechanisms of bone regeneration, screening tissue engineering materials, and promoting bone regeneration and repair. They offer promising applications in bone regeneration research. |
| فهرسة مساهمة: |
Keywords: 3D cell culture; Bone organoids; Bone regeneration; Tissue engineering; skeletal diseases |
| تواريخ الأحداث: |
Date Created: 20231126 Date Completed: 20231128 Latest Revision: 20231128 |
| رمز التحديث: |
20231128 |
| DOI: |
10.3233/SHTI230890 |
| PMID: |
38007789 |
| قاعدة البيانات: |
MEDLINE |
