دورية أكاديمية
أعرض في EDS

Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho.

التفاصيل البيبلوغرافية
العنوان: Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho.
المؤلفون: Narvestad-Bøttger H; Department of Clinical Genetics., Winther-Larsen A; Department of Clinical Biochemistry and Clinical Medicine., Haugbølle Bjerre J; Department of Pathology., Dziegiel MH; Department of Immunology, Copenhagen University Hospital, Denmark., Hansen AT; Department of Immunology, Copenhagen University Hospital, Denmark., Hasle H; Department of Pediatrics and Adolescent Medicine and Department of Clinical Medicine, Aarhus University Hospital, Aarhus.
المصدر: Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2024 Jan 01; Vol. 46 (1), pp. e111-e114. Date of Electronic Publication: 2023 Nov 24.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505928 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3678 (Electronic) Linking ISSN: 10774114 NLM ISO Abbreviation: J Pediatr Hematol Oncol Subsets: MEDLINE
أسماء مطبوعة: Publication: 1998- : Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: New York, NY : Raven Press, c1995-
مواضيع طبية MeSH: Reticulocytosis* , Hemoglobins, Abnormal*, Male ; Humans ; Child, Preschool ; Splenectomy/adverse effects ; Erythrocyte Inclusions
مستخلص: Background: Patients with Hb Mizuho may be splenectomized at a young age to decrease their need for blood transfusions.
Observations: Transfusion-dependency decreased dramatically in a 4-year-old white boy with Hb Mizuho after splenectomy. Surprisingly, he developed reticulocytosis (>1000×10 9 /L) with a peak reticulocyte percentage of 49%, and erythrocyte abnormalities, including Heinz bodies, Howell-Jolly bodies, and basophilic stippling. Manual reticulocyte counting and flow cytometric measurement with anti-CD71 antibodies supported a truly elevated reticulocyte count.
Conclusions: We propose possible explanations for the extreme reticulocytosis that arose postsplenectomy and compare the reticulocyte count in the present case with previously published cases.
Competing Interests: The authors declare no conflict of interest.
(Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
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المشرفين على المادة: 64366-48-9 (hemoglobin Mizuho)
0 (Hemoglobins, Abnormal)
تواريخ الأحداث: Date Created: 20231127 Date Completed: 20240104 Latest Revision: 20240104
رمز التحديث: 20240104
DOI: 10.1097/MPH.0000000000002790
PMID: 38011049
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-3678
DOI:10.1097/MPH.0000000000002790