دورية أكاديمية
Altered Perception of the Bistable Motion Quartet in Albinism.
| العنوان: | Altered Perception of the Bistable Motion Quartet in Albinism. |
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| المؤلفون: | Al-Nosairy KO; Department of Ophthalmology, Otto-von-Guericke University, Magdeburg, Germany., Quanz EV; Department of Ophthalmology, Otto-von-Guericke University, Magdeburg, Germany., Eick CM; Department of Ophthalmology, Otto-von-Guericke University, Magdeburg, Germany., Hoffmann MB; Department of Ophthalmology, Otto-von-Guericke University, Magdeburg, Germany.; Center for Behavioral Brain Sciences, Otto-von-Guericke University, Magdeburg, Germany., Kornmeier J; Institute for Frontier Areas of Psychology and Mental Health, Freiburg, Germany.; Department of Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany. |
| المصدر: | Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2023 Nov 01; Vol. 64 (14), pp. 39. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Brookline Ma : Association For Research In Vision And Ophthalmology (Arvo) Original Publication: St. Louis, Mosby. |
| مواضيع طبية MeSH: | Albinism* , Motion Perception* , Nystagmus, Pathologic* , Optic Nerve*, Humans ; Optic Chiasm |
| مستخلص: | Purpose: Perception of the motion quartet (MQ) alternates between horizontal and vertical motion, with a bias toward vertical motion. This vertical bias has been explained by the dominance of intrahemispheric processing. In albinism, each hemisphere receives input from both visual hemifields owing to enhanced crossing of the optic nerves at the optic chiasm. This might affect the perception of the ambiguous MQ and particularly the vertical bias. Methods: The effect of optic nerve misrouting in persons with albinism and nystagmus (PWA, n = 14) on motion perception for MQ was compared with healthy controls (HC; n = 11) and with persons with nystagmus in the absence of optic nerve misrouting (PWN; n = 12). We varied the ratio of horizontal and vertical distances of MQ dots (aspect ratio [AR]) between 0.75 and 1.25 and compared the percentages of horizontal and vertical motion percepts as a function of AR between groups. Results: For HC, the probability of vertical motion perception increased as a sigmoid function with increasing AR exhibiting the expected vertical percept bias (mean, 58%; median, 54%; vertical motion percepts). PWA showed a surprisingly strong horizontal bias independent of the AR with a mean of 11% (median, 10%) vertical motion percepts. The PWN was in between PWA and HC, with a mean of 34% (median, 47%) vertical perception. Nystagmus alone is unlikely to explain this pattern of results because PWA and PWN had comparable fixation stabilities. Conclusions: The strong horizontal bias observed in PWA and PWN might partly result from the horizontal nystagmus. The even stronger horizontal bias in PWA indicates that the intrahemispherical corepresentation of both visual hemifields may play an additional role. The altered perception of the MQ in PWA opens opportunities to (i) understand the interplay of stability and plasticity in altered visual pathway conditions and (ii) identify visual pathway abnormalities with a perception-based test using the MQ. |
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| تواريخ الأحداث: | Date Created: 20231128 Date Completed: 20231129 Latest Revision: 20231205 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC10691394 |
| DOI: | 10.1167/iovs.64.14.39 |
| PMID: | 38015177 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1552-5783 |
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| DOI: | 10.1167/iovs.64.14.39 |