دورية أكاديمية
أعرض في EDS

Quantification of Straylight Induced by Silicone Oil Adherent to Intraocular Lenses of Different Materials.

التفاصيل البيبلوغرافية
العنوان: Quantification of Straylight Induced by Silicone Oil Adherent to Intraocular Lenses of Different Materials.
المؤلفون: Hammer M; From the Department of Ophthalmology, University Clinic Heidelberg (M.H., L.B., A.S., R.K., G.Ł., G.U.A.); David J Apple Laboratory for Vision Research (M.H., L.B., S.S., D.M., A.S., R.K., G.Ł., G.U.A.)., Britz L; From the Department of Ophthalmology, University Clinic Heidelberg (M.H., L.B., A.S., R.K., G.Ł., G.U.A.); David J Apple Laboratory for Vision Research (M.H., L.B., S.S., D.M., A.S., R.K., G.Ł., G.U.A.)., Schickhardt S; David J Apple Laboratory for Vision Research (M.H., L.B., S.S., D.M., A.S., R.K., G.Ł., G.U.A.)., Lieberwirth I; Heidelberg, Department of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Mainz (I.L.)., Munro D; David J Apple Laboratory for Vision Research (M.H., L.B., S.S., D.M., A.S., R.K., G.Ł., G.U.A.)., Uhl P; Institute for Pharmacy and Molecular Biotechnology, Heidelberg (P.U.), Germany., Scheuerle A; From the Department of Ophthalmology, University Clinic Heidelberg (M.H., L.B., A.S., R.K., G.Ł., G.U.A.); David J Apple Laboratory for Vision Research (M.H., L.B., S.S., D.M., A.S., R.K., G.Ł., G.U.A.)., Khoramnia R; From the Department of Ophthalmology, University Clinic Heidelberg (M.H., L.B., A.S., R.K., G.Ł., G.U.A.)., Łabuz G; From the Department of Ophthalmology, University Clinic Heidelberg (M.H., L.B., A.S., R.K., G.Ł., G.U.A.); David J Apple Laboratory for Vision Research (M.H., L.B., S.S., D.M., A.S., R.K., G.Ł., G.U.A.)., Auffarth GU; From the Department of Ophthalmology, University Clinic Heidelberg (M.H., L.B., A.S., R.K., G.Ł., G.U.A.); David J Apple Laboratory for Vision Research (M.H., L.B., S.S., D.M., A.S., R.K., G.Ł., G.U.A.). Electronic address: Gerd.auffarth@med.uni-heidelberg.de.
المصدر: American journal of ophthalmology [Am J Ophthalmol] 2024 Jun; Vol. 262, pp. 192-198. Date of Electronic Publication: 2023 Nov 26.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : New York, NY : Elsevier Science
Original Publication: [Chicago, etc., Ophthalmic Pub. Co., etc.]
مواضيع طبية MeSH: Silicone Oils*/adverse effects , Lenses, Intraocular*/adverse effects , Scattering, Radiation* , Endotamponade*, Humans ; Light/adverse effects ; Microscopy, Electron, Scanning ; Glare ; Hydrophobic and Hydrophilic Interactions
مستخلص: Purpose: A complication of using silicone oil as an intraocular endotamponade is its adhesion to intraocular lenses (IOLs). Forward light scattering is a measure to quantify the optical disturbance caused by adherent oil droplets. We tested the straylight caused by silicone oil adhesion to different IOLs and examined whether an approved cleaning solution, F4H5, reverses the induced straylight.
Design: An experimental study.
Methods: Two hydrophobic acrylic IOL models and 1 hydrophilic model with a hydrophobic surface (n = 8 per model: 24 lenses) had straylight measured before contact with silicone oils, providing a baseline for subsequent testing: 12 lenses with lighter-than-water silicone oil (Siluron 2000) and 12 with heavier-than-water oil (Densiron 68). The final measurement was performed after cleansing with F4H5 when we used scanning electron and light microscopy to detect surface changes.
Results: Straylight was majorly increased in IOLs with adherent silicone oil (baseline vs adherent oil median 3.1 [2.1, 3.9] and 39.7 [22.7, 87.8] deg 2 /sr, respectively; P < .001). No difference was seen between heavier- and lighter-than-water silicone oils. Between IOL types, induced straylight varied significantly, with 1 hydrophobic model reaching the highest average straylight. F4H5 significantly reduced straylight values in all IOL types (median 9.4 [5.4, 13.8] deg 2 /sr). The microscopy revealed surface changes on the IOLs even after cleaning.
Conclusions: Silicone oil adhesion to IOLs can induce amounts of straylight known to cause severe optical disturbance. F4H5 cleansing solution reversed straylight values to only slightly increased values. We found no difference in straylight formation between the lighter- and heavier-than-water silicone oils.
(Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.)
تواريخ الأحداث: Date Created: 20231128 Date Completed: 20240516 Latest Revision: 20240516
رمز التحديث: 20240517
DOI: 10.1016/j.ajo.2023.11.018
PMID: 38016528
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1891
DOI:10.1016/j.ajo.2023.11.018