دورية أكاديمية
أعرض في EDS

Body Mass Index Profile of Adult Patients with Inflammatory Bowel Disease in a Multicenter Study in Northeastern Brazil.

التفاصيل البيبلوغرافية
العنوان: Body Mass Index Profile of Adult Patients with Inflammatory Bowel Disease in a Multicenter Study in Northeastern Brazil.
المؤلفون: Lima JS; Department of Gastroenterology, Hospital das Clínicas, Federal University of Pernambuco, Recife, Pernambuco, Brazil., de Brito CAA; Department of Gastroenterology, Hospital das Clínicas, Federal University of Pernambuco, Recife, Pernambuco, Brazil.; Department of Gastroenterology, Member of Organização Brasileira de Doença de Crohn e Retocolite - GEDIIB, São Paulo, Brazil.; Department of Internal Medicine, Center of Medical Sciences of Federal University of Pernambuco, Pernambuco, Brazil.; Department of Immunology, Autoimune Research Institute, Recife, Pernambuco, Brazil., Celani LMS; Department of Gastroenterology, Member of Organização Brasileira de Doença de Crohn e Retocolite - GEDIIB, São Paulo, Brazil.; Department of Gastroenterology, Onofre Lopes Hospital, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., de Araújo MVT; Department of Gastroenterology, Member of Organização Brasileira de Doença de Crohn e Retocolite - GEDIIB, São Paulo, Brazil.; Department of Gastroenterology, Lauro Wanderley Hospital, Federal University of Paraíba, João Pessoa, Paraíba, Brazil., de Lucena MT; Department of Coloproctology, Barão de Lucena Hospital, Recife, Pernambuco, Brazil., Vasconcelos GBS; Department of Gastroenterology, Hospital das Clínicas, Federal University of Pernambuco, Recife, Pernambuco, Brazil.; Department of Gastroenterology, Member of Organização Brasileira de Doença de Crohn e Retocolite - GEDIIB, São Paulo, Brazil.; Department of Gastroenterology, University of Pernambuco, Recife, Pernambuco, Brazil., Lima GAS; Department of Gastroenterology, Hospital das Clínicas, Federal University of Pernambuco, Recife, Pernambuco, Brazil.; Department of Gastroenterology, Member of Organização Brasileira de Doença de Crohn e Retocolite - GEDIIB, São Paulo, Brazil.; Department of Immunology, Autoimune Research Institute, Recife, Pernambuco, Brazil., Nóbrega FJF; Department of Gastroenterology, Lauro Wanderley Hospital, Federal University of Paraíba, João Pessoa, Paraíba, Brazil., Diniz GTN; Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Brazil., Lucena-Silva N; Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Brazil., Maio R; Department of Nutrition, Federal University of Pernambuco, Recife, Pernambuco, Brazil., Martinelli VF; Department of Gastroenterology, Hospital das Clínicas, Federal University of Pernambuco, Recife, Pernambuco, Brazil.; Department of Gastroenterology, Member of Organização Brasileira de Doença de Crohn e Retocolite - GEDIIB, São Paulo, Brazil.; Department of Immunology, Autoimune Research Institute, Recife, Pernambuco, Brazil.
المصدر: Clinical and experimental gastroenterology [Clin Exp Gastroenterol] 2023 Nov 14; Vol. 16, pp. 213-224. Date of Electronic Publication: 2023 Nov 14 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101532800 Publication Model: eCollection Cited Medium: Print ISSN: 1178-7023 (Print) Linking ISSN: 11787023 NLM ISO Abbreviation: Clin Exp Gastroenterol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Auckland, N.Z.] : Dove Medical Press, c2008-
مستخلص: Purpose: Inflammatory bowel disease (IBD) is a disease of increasing prevalence in developing countries. Obesity has emerged as a potential risk for IBD; however, the data in the literature are conflicting, and relevant studies in Brazil are limited. Here, we report body mass index profile (BMI) of patients with IBD treated at reference centers in three states of northeastern Brazil.
Patients and Methods: Observational descriptive study conducted from January 2021 through December 2021 in patient with IBD.
Results: Of 470 patients with IBD, 194 (41%) were classified as normal weight, 42 (9%) as underweight, 155 (33%) as overweight, and 79 (17%) as obese; CD patients were significantly more likely to be underweight than UC patients ( p =0.031)Overweight patients were older (median age: 47 years) than normal-weight and underweight patients at diagnosis (38.5 and 35.5 years, respectively [ p <0.0001]). IBD onset and diagnosis among overweight and obese individuals were associated with older age. More extensive disease behavior patterns predominated in UC, while forms associated with complications were prevalent in CD, irrespective of nutritional status. There was a higher frequency of compatible symptoms with axial joint inflammation among obese patients ( p =0.005) and a lower frequency of compatible symptoms with peripheral joint inflammation in underweight patients ( p =0.044) than in patients of normal weight. No significant difference in the frequency of different drug or surgical treatments was observed among the groups.
Conclusion: Despite the predominance of overweight and obesity in patients with IBD, no differences in the patterns of disease were seen between the overweight and normal-weight groups; however, obesity was associated with IBD onset in older adults and a higher frequency compatible symptom with axial joint inflammation. These data reinforce the importance of monitoring the nutritional status of IBD patients and the need for a multidisciplinary approach, as recommended in the current guidelines.
Competing Interests: The authors report no conflicts of interest in this work.
(© 2023 Lima et al.)
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فهرسة مساهمة: Keywords: Crohn’s disease; obesity; overweight; ulcerative colitis
تواريخ الأحداث: Date Created: 20231129 Latest Revision: 20231201
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10656846
DOI: 10.2147/CEG.S436699
PMID: 38023814
قاعدة البيانات: MEDLINE
الوصف
تدمد:1178-7023
DOI:10.2147/CEG.S436699