دورية أكاديمية
أعرض في EDS

Comparison of clinical outcomes among patients with isolated axial vs muscular calf vein thrombosis: A systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Comparison of clinical outcomes among patients with isolated axial vs muscular calf vein thrombosis: A systematic review and meta-analysis.
المؤلفون: Wang C; Third Xiangya Hospital, Central South University, Changsha, Hunan, China., Shi C; Third Xiangya Hospital, Central South University, Changsha, Hunan, China., Guo R; Third Xiangya Hospital, Central South University, Changsha, Hunan, China., Wu T; Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, China. Electronic address: wutian-1987@163.com.
المصدر: Journal of vascular surgery. Venous and lymphatic disorders [J Vasc Surg Venous Lymphat Disord] 2024 Mar; Vol. 12 (2), pp. 101727. Date of Electronic Publication: 2023 Dec 02.
نوع المنشور: Systematic Review; Meta-Analysis; Journal Article; Comparative Study
اللغة: English
بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101607771 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-3348 (Electronic) NLM ISO Abbreviation: J Vasc Surg Venous Lymphat Disord
أسماء مطبوعة: Original Publication: New York, NY : Elsevier Inc., c2013-
مواضيع طبية MeSH: Venous Thrombosis*/diagnostic imaging , Venous Thrombosis*/therapy , Venous Thrombosis*/physiopathology , Recurrence* , Leg*/blood supply , Hemorrhage*, Humans ; Treatment Outcome ; Risk Factors ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/therapy ; Venous Thromboembolism ; Anticoagulants/therapeutic use
مستخلص: Objective: Thrombi in the axial calf veins have quite different anatomical and physiological characteristics from that in the muscular calf veins, but their treatment was usually addressed in the same manner. We performed a meta-analysis of randomized and cohort studies to compare clinical outcomes among patients with isolated axial vs muscular calf deep vein thrombosis (DVT).
Methods: Recurrent venous thromboembolism (VTE) was selected as the primary outcome. Resolution, proximal propagation of calf DVT, pulmonary embolism (PE), major bleeds, and clinically relevant non-major bleeds were separately analyzed as secondary outcomes. Data were pooled and compared with risk ratio (RR) and 95% confidence interval (CI).
Results: Thirteen studies, consisting of 4889 patients, met the inclusion criteria and were included for analysis. A greater rate of recurrent VTE (FE model: RR, 1.23; 95% CI, 1.00-1.53; I 2  = 29%), resolution (FE model: RR, 1.32; 95% CI, 1.01-1.72; I 2  = 31%), proximal propagation (FE model: RR, 1.63; 95% CI, 1.10-2.41; I 2  = 40%), and PE (FE model: RR, 2.79; 95% CI, 1.31-5.95; I 2  = 0%) in the axial group compared with the muscular group. There was no difference in the pooled estimates for major bleeds (FE model: RR, 1.09; 95% CI, 0.61-1.95; I 2  = 0%), and clinically relevant non-major bleeds (FE model: RR, 1.80; 95% CI, 0.93-3.48) in the axial and muscular arms.
Conclusions: Patients with calf DVT limited to muscular veins might have a lower rate of recurrent VTE, resolution, proximal propagation, and PE vs those with axial calf vein involvement and exhibited similar safety outcomes.
Competing Interests: Disclosures None.
(Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Anticoagulants; Calf vein thrombosis; Distal deep vein thrombosis; Pulmonary embolism; Venous thromboembolism
المشرفين على المادة: 0 (Anticoagulants)
تواريخ الأحداث: Date Created: 20231203 Date Completed: 20240807 Latest Revision: 20240814
رمز التحديث: 20240815
DOI: 10.1016/j.jvsv.2023.101727
PMID: 38043681
قاعدة البيانات: MEDLINE
الوصف
تدمد:2213-3348
DOI:10.1016/j.jvsv.2023.101727