دورية أكاديمية
Holter Electrocardiographic Approach to Predicting Outcomes of Pediatric Patients With Long QT Syndrome.
| العنوان: | Holter Electrocardiographic Approach to Predicting Outcomes of Pediatric Patients With Long QT Syndrome. |
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| المؤلفون: | Yoshinaga M; Department of Pediatrics, National Hospital Organization Kagoshima Medical Center.; Orange Medical and Welfare Center for Severe Motor and Intellectual Disabilities., Ninomiya Y; Department of Pediatrics, National Hospital Organization Kagoshima Medical Center., Tanaka Y; Department of Pediatrics, National Hospital Organization Kagoshima Medical Center., Fukuyama M; Department of Cardiovascular Medicine, Shiga University of Medical Science., Kato K; Department of Cardiovascular Medicine, Shiga University of Medical Science., Ohno S; Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center., Horie M; Department of Cardiovascular Medicine, Shiga University of Medical Science., Ogata H; Graduate School of Kagawa Nutrition University. |
| المصدر: | Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2024 Jun 25; Vol. 88 (7), pp. 1176-1184. Date of Electronic Publication: 2023 Dec 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Japanese Circulation Society Country of Publication: Japan NLM ID: 101137683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-4820 (Electronic) Linking ISSN: 13469843 NLM ISO Abbreviation: Circ J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kyoto, Japan : Japanese Circulation Society, [2002- |
| مواضيع طبية MeSH: | Long QT Syndrome*/diagnosis , Long QT Syndrome*/physiopathology , Electrocardiography, Ambulatory*/methods, Humans ; Retrospective Studies ; Child ; Male ; Female ; Child, Preschool ; Adolescent ; Prognosis ; Infant ; Predictive Value of Tests ; Heart Rate |
| مستخلص: | Background: This study was performed to clarify the clinical findings of pediatric patients diagnosed with long QT syndrome (LQTS) through electrocardiographic screening programs and to predict their outcome using Holter electrocardiographic approaches.Methods and Results: This retrospective study included pediatric patients with a Schwartz score of ≥3.5 who visited the National Hospital Organization Kagoshima Medical Center between April 2005 and March 2019. Resting 12-lead and Holter electrocardiograms were recorded at every visit. The maximum resting QTc and maximum Holter QTc values among all recordings were used for statistical analyses. To test the prognostic value of QTc for the appearance of cardiac events after the first hospital visit, receiver operating characteristic curves were used to calculate the area under the curve (AUC). Among 207 patients, 181 (87%) were diagnosed through screening programs. The prevalence of cardiac events after the first hospital visit was 4% (8/207). Among QTc at diagnosis, maximum resting QTc, and maximum Holter QTc, only maximum Holter QTc value was a predictor (P=0.02) of cardiac events after the hospital visit in multivariate regression analysis. The AUC of the maximum Holter QTc was significantly superior to that of maximum resting QTc. Conclusions: The maximum Holter QTc value can be used to predict the appearance of symptoms in pediatric patients with LQTS. |
| فهرسة مساهمة: | Keywords: Children; Holter electrocardiogram; Long QT syndrome; Prognosis; Screening |
| تواريخ الأحداث: | Date Created: 20231203 Date Completed: 20240626 Latest Revision: 20240626 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1253/circj.CJ-23-0409 |
| PMID: | 38044147 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1347-4820 |
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| DOI: | 10.1253/circj.CJ-23-0409 |