دورية أكاديمية
Pediatric Corneal Transplantation in Uyo, Nigeria: Early Experiences.
| العنوان: | Pediatric Corneal Transplantation in Uyo, Nigeria: Early Experiences. |
|---|---|
| المؤلفون: | Nkanga ED; Paediatric Ophthalmology and Strabismus Unit, Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Umana UE; Department of Ophthalmology, Marion Eye Centre, Marion, Illinois, USA., Ibanga AA; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Nkanga ED; Department of Pediatrics, All Saints University of Medicine, Common Wealth of Dominica, Rivers State, Nigeria., Ezeh EI; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Ani EU; Department of Ophthalmology, The Ophthalmic Specialists, Port Harcourt, Rivers State, Nigeria., Nkanga DG; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Etim BA; Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria., Akpan SI; Department of Ophthalmology, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, Nigeria. |
| المصدر: | Nigerian journal of clinical practice [Niger J Clin Pract] 2023 Nov 01; Vol. 26 (11), pp. 1772-1776. Date of Electronic Publication: 2023 Dec 04. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications Country of Publication: India NLM ID: 101150032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1119-3077 (Print) NLM ISO Abbreviation: Niger J Clin Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Mumbai : Medknow Publications Original Publication: [Lagos?] : Medical and Dental Consultants' Association of Nigeria |
| مواضيع طبية MeSH: | Corneal Transplantation* , Corneal Diseases*/epidemiology , Corneal Diseases*/surgery, Male ; Humans ; Child ; Child, Preschool ; Nigeria ; Keratoplasty, Penetrating ; Treatment Outcome ; Retrospective Studies ; Blindness/epidemiology ; Blindness/etiology ; Blindness/surgery |
| مستخلص: | Abstract: The burden of avoidable blindness from corneal disease is significantly higher where access to specialist eye care, the cost of treatment and the treatment infrastructure including eye banking, are beyond the reach of the impoverished masses. Corneal transplantation in children is challenging: it is more technically complex; patients often require multiple examinations under general anaesthesia to optimize treatment outcomes. There is also the increased risk of several complications including graft dehiscence, infection, rejection, and inappropriate patient or caregiver care. However, when successful, it restores vision. We present a report of our initial experience with penetrating keratoplasty in 2 children with blinding corneal disease in Uyo, Nigeria. Corneal transplantation history was retrieved and data (including data on age, sex, aetiology of corneal disease, indications for corneal transplantation, pre-operative and post-operative visual acuity and intraocular pressure measurements) was extracted for this report. Both patients had standard penetrating keratoplasty performed by one surgeon, under general anaesthesia. Case one was a 10-year-old male presenting with profound visual impairment from congenital hereditary endothelial dystrophy. His best corrected post-operative visual acuity was 6/24. Case two was a 3-year-old male with vision loss due to a corneal leucoma following treated herpes simplex keratitis. Post-operatively, his best corrected visual acuity improved to 6/12. Corneal graft tissue remained clear at more than 3 years of follow-up. Although amblyopia was a notable co-morbidity, corneal transplantation significantly improved their vision. Corneal banking services are advocated for in resource-limited settings where the magnitude of corneal blindness is greatest. (Copyright © 2023 Copyright: © 2023 Nigerian Journal of Clinical Practice.) |
| References: | Pascolini D, Mariotti SP. Global estimates of visual impairment:2010. Br J Ophthalmol 2011;96:614–8. Waziri-Erameh JM, Omoti AE, Chukwuka IO. The problem of retro-prosthetic membrane following keratoprosthesis in Nigerian eyes. Am J Case Rep 2008;9:211–5. Mun-Wei L, Md Said H, Punitan R, Ibrahim M, Shatriah I. Indications, clinical outcomes, and survival rate of pediatric penetrating keratoplasty in suburban Malaysia:A 10-year experience. Cureus 2018;10:e3744. doi:10.7759/cureus.3744. (PMID: 10.7759/cureus.3744) Umana UI, Ezeh EI, Nkanga DG, Utam UA, Ibanga AA, Etim BA, et al. Early experience with penetrating keratoplasty in South-South Nigeria:Initial audit of indications and outcome. Arch Int Surg 2018;8:101–7. Trief D, Marquezan MC, Rapuano CJ, Prescott CR. Pediatric corneal transplants. Curr Opin Ophthalmol 2017;28:477–84. Ezeh EI, Ezeh RN. Contact corneal thermal burn from domestic electric clothes iron in a female teenager:A case report. Calabar J Health Sci 2021;5:28–30. Sharma A, Sharma R. pediatric corneal transplant surgery:Challenges for successful outcome. Nepal J Ophthalmol 2019;11:197–210. Kannabiran C, Chaurasia S, Ramappa M, Mootha VV. Update on the genetics of corneal endothelial dystrophies. Indian J Ophthalmol 2022;70:2239–48. Al-Ghamdi A, Al-Rajhi A, Wagoner MD. Primary pediatric keratoplasty:Indications, graft survival, and visual outcome. J AAPOS 2007;11:41–7. Zhu AY, Marquezan MC, Kraus CL, Prescott CR. Pediatric corneal transplants:Review of current practice patterns. Cornea 2018;37:973–80. Javadi MA, Baradaran AR. Penetrating keratoplasty in young children with congenital hereditary endothelial dystrophy. Cornea 2003;22:420–3. Özdemir B, Kubaloğlu A, Koytak A, Coskun E, Çinar Y, Sari ES, et al. Penetrating keratoplasty in congenital hereditary endothelial dystrophy. Cornea 2012;31:359–65. Mittal V, Sehdev N, Mittal R. Descemet membrane endothelial keratoplasty in congenital hereditary endothelial dystrophy:Initial experiences. Cornea 2021;40:972–6. Patel HY, Ormonde S, Brookes NH, Moffatt LS, McGhee CNJ. The indications and outcome of paediatric corneal transplantation in New Zealand:1991-2003. Br J Ophthalmol 2005;89:404–8. Kusumesh R, Vanathi M. Graft rejection in pediatric penetrating keratoplasty:Clinical features and outcomes. Oman J Ophthalmol 2015;8:33–7. |
| تواريخ الأحداث: | Date Created: 20231204 Date Completed: 20231205 Latest Revision: 20231205 |
| رمز التحديث: | 20240628 |
| DOI: | 10.4103/njcp.njcp_459_23 |
| PMID: | 38044787 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1119-3077 |
|---|---|
| DOI: | 10.4103/njcp.njcp_459_23 |