دورية أكاديمية
Vasopressin in vasoplegic shock in surgical patients: systematic review and meta-analysis.
| العنوان: | Vasopressin in vasoplegic shock in surgical patients: systematic review and meta-analysis. |
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| المؤلفون: | Szeles TF; Universidade de São Paulo - Medical School - Anesthesiology Department - São Paulo (SP) - Brazil., Almeida JP; Universidade de São Paulo - Medical School - Anesthesiology Department - São Paulo (SP) - Brazil., Cruz JASD; Universidade de São Paulo - Medical School - Anesthesiology Department - São Paulo (SP) - Brazil., Artifon ELA; Universidade de São Paulo - Medical School - Anesthesiology Department - São Paulo (SP) - Brazil. |
| المصدر: | Acta cirurgica brasileira [Acta Cir Bras] 2023 Dec 01; Vol. 38, pp. e387523. Date of Electronic Publication: 2023 Dec 01 (Print Publication: 2023). |
| نوع المنشور: | Meta-Analysis; Systematic Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina Country of Publication: Brazil NLM ID: 9103983 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2674 (Electronic) Linking ISSN: 01028650 NLM ISO Abbreviation: Acta Cir Bras Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Sao Paulo : Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina Original Publication: São Paulo : A Sociedade, |
| مواضيع طبية MeSH: | Vasopressins*/therapeutic use , Vasoplegia*/drug therapy, Humans ; Vasoconstrictor Agents/therapeutic use ; Norepinephrine/therapeutic use ; Blood Pressure |
| مستخلص: | Purpose: Vasoplegia, or vasoplegic shock, is a syndrome whose main characteristic is reducing blood pressure in the presence of a standard or high cardiac output. For the treatment, vasopressors are recommended, and the most used is norepinephrine. However, new drugs have been evaluated, and conflicting results exist in the literature. Methods: This is a systematic review of the literature with meta-analysis, written according to the recommendations of the PRISMA report. The SCOPUS, PubMed, and ScienceDirect databases were used to select the scientific articles included in the study. Searches were conducted in December 2022 using the terms "vasopressin," "norepinephrine," "vasoplegic shock," "postoperative," and "surgery." Meta-analysis was performed using Review Manager (RevMan) 5.4. The endpoint associated with the study was efficiency in treating vasoplegic shock and reduced risk of death. Results: In total, 2,090 articles were retrieved; after applying the inclusion and exclusion criteria, ten studies were selected to compose the present review. We found no significant difference when assessing the outcome mortality comparing vasopressin versus norepinephrine (odds ratio = 1.60; confidence interval 0.47-5.50), nor when comparing studies on vasopressin versus placebo. When we analyzed the length of hospital stay compared to the use of vasopressin and norepinephrine, we identified a shorter length of hospital stay in cases that used vasopressin; however, the meta-analysis did not demonstrate statistical significance. Conclusions: Considering the outcomes included in our study, it is worth noting that most studies showed that using vasopressin was safe and can be considered in managing postoperative vasoplegic shock. |
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| المشرفين على المادة: | 11000-17-2 (Vasopressins) 0 (Vasoconstrictor Agents) X4W3ENH1CV (Norepinephrine) |
| تواريخ الأحداث: | Date Created: 20231206 Date Completed: 20231211 Latest Revision: 20231211 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC10691175 |
| DOI: | 10.1590/acb387523 |
| PMID: | 38055405 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-2674 |
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| DOI: | 10.1590/acb387523 |