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Updating the striatal-pallidal wiring diagram.

التفاصيل البيبلوغرافية
العنوان: Updating the striatal-pallidal wiring diagram.
المؤلفون: Fang LZ; Washington University Pain Center, Department of Anesthesiology, St. Louis, MO, USA.; Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, Newfoundland and Labrador, Canada., Creed MC; Washington University Pain Center, Department of Anesthesiology, St. Louis, MO, USA. meaghan.creed@wustl.edu.; Departments of Psychiatry, Neuroscience and Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA. meaghan.creed@wustl.edu.
المصدر: Nature neuroscience [Nat Neurosci] 2024 Jan; Vol. 27 (1), pp. 15-27. Date of Electronic Publication: 2023 Dec 06.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE
أسماء مطبوعة: Publication: <2002->: New York, NY : Nature Publishing Group
Original Publication: New York, NY : Nature America Inc., c1998-
مواضيع طبية MeSH: Corpus Striatum* , Globus Pallidus*, Basal Ganglia/physiology ; Neurons ; Neostriatum ; Neural Pathways/physiology
مستخلص: The striatal and pallidal complexes are basal ganglia structures that orchestrate learning and execution of flexible behavior. Models of how the basal ganglia subserve these functions have evolved considerably, and the advent of optogenetic and molecular tools has shed light on the heterogeneity of subcircuits within these pathways. However, a synthesis of how molecularly diverse neurons integrate into existing models of basal ganglia function is lacking. Here, we provide an overview of the neurochemical and molecular diversity of striatal and pallidal neurons and synthesize recent circuit connectivity studies in rodents that takes this diversity into account. We also highlight anatomical organizational principles that distinguish the dorsal and ventral basal ganglia pathways in rodents. Future work integrating the molecular and anatomical properties of striatal and pallidal subpopulations may resolve controversies regarding basal ganglia network function.
(© 2023. Springer Nature America, Inc.)
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معلومات مُعتمدة: R01 DA058755 United States DA NIDA NIH HHS
تواريخ الأحداث: Date Created: 20231206 Date Completed: 20240110 Latest Revision: 20240110
رمز التحديث: 20240110
DOI: 10.1038/s41593-023-01518-x
PMID: 38057614
قاعدة البيانات: MEDLINE
الوصف
تدمد:1546-1726
DOI:10.1038/s41593-023-01518-x