دورية أكاديمية
Regular Practice of Physical Activity Improves Cholesterol Transfers to High-Density Lipoprotein (HDL) and Other HDL Metabolic Parameters in Older Adults.
العنوان: | Regular Practice of Physical Activity Improves Cholesterol Transfers to High-Density Lipoprotein (HDL) and Other HDL Metabolic Parameters in Older Adults. |
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المؤلفون: | Braga PGS; Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-900, Brazil., Freitas FR; Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-900, Brazil., Bachi ALL; Post-Graduation Program in Health Sciences, Santo Amaro University (UNISA), Sao Paulo 04829-300, Brazil., Amirato GR; Centro Educacional e Esportivo Mane Garrincha, Secretaria Municipal de Esportes, Lazer e Recreacao, Sao Paulo 04039-034, Brazil., Baroni RV; Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-900, Brazil., Alves MJNN; Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-900, Brazil., Vieira RP; Post-Graduate Program in Sciences of Human Movement and Rehabilitation, Universidade Federal de Sao Paulo (UNIFESP), Santos 11060-001, Brazil.; Post-Graduate Program in Human Movement and Rehabilitation and in Pharmaceutical Sciences, Evangelical University of Goiás (Unievangélica), Anápolis 75083-515, Brazil.; Post-Graduate Program in Bioengineering, Universidade Brasil, São Paulo 08230-030, Brazil., Vaisberg MW; Departamento de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo 04023-062, Brazil., Aldin MN; Departamento de Nutricao, Faculdade de Saude Publica da Universidade de São Paulo (FSP-USP), Sao Paulo 01246-904, Brazil., Kalil Filho R; Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-900, Brazil., Figueiredo Neto AM; Instituto de Fisica (IF), Universidade de Sao Paulo, Sao Paulo 05508-090, Brazil., Damasceno NRT; Departamento de Nutricao, Faculdade de Saude Publica da Universidade de São Paulo (FSP-USP), Sao Paulo 01246-904, Brazil., Tavoni TM; Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-900, Brazil., Maranhão RC; Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-900, Brazil.; Faculdade de Ciencias Farmaceuticas, Universidade de Sao Paulo, Sao Paulo 05508-000, Brazil. |
المصدر: | Nutrients [Nutrients] 2023 Nov 22; Vol. 15 (23). Date of Electronic Publication: 2023 Nov 22. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI Publishing |
مواضيع طبية MeSH: | Lipoproteins, HDL* , Antioxidants*, Humans ; Aged ; Aryldialkylphosphatase ; Cholesterol ; Cholesterol Esters ; Exercise ; Cholesterol, HDL |
مستخلص: | The effects of regular physical activity on two important anti-atherosclerosis functions of high-density lipoprotein (HDL), namely its capacity to receive both forms of cholesterol and its anti-oxidant function, were investigated in this study comparing older adults with young individuals. One-hundred and eight healthy adult individuals were enrolled and separated into the following groups: active older (60-80 yrs, n = 24); inactive older (60-79 yrs, n = 21); active young (20-34 yrs, n = 39); and inactive young (20-35 yrs, n = 24). All performed cardiopulmonary tests. Blood samples were collected in order to assess the following measures: lipid profile, HDL anti-oxidant capacity, paraoxonase-1 activity, HDL subfractions, and lipid transfer to HDL. Comparing active older and active young groups with inactive older and inactive young groups, respectively, the active groups presented higher HDL-C levels ( p < 0.01 for both comparisons), unesterified cholesterol transfer ( p < 0.01, p < 0.05), and intermediate and larger HDL subfractions ( p < 0.001, p < 0.01) than the respective inactive groups. In addition, the active young group showed higher esterified cholesterol transfer than the inactive young group ( p < 0.05). As expected, the two active groups had higher VO |
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معلومات مُعتمدة: | 2014/03742-0 São Paulo Research Foundation |
فهرسة مساهمة: | Keywords: HDL function; HDL metabolism; aging; cholesterol; physical activity |
المشرفين على المادة: | 0 (Lipoproteins, HDL) 0 (Antioxidants) EC 3.1.8.1 (Aryldialkylphosphatase) 97C5T2UQ7J (Cholesterol) 0 (Cholesterol Esters) 0 (Cholesterol, HDL) |
تواريخ الأحداث: | Date Created: 20231209 Date Completed: 20231216 Latest Revision: 20231216 |
رمز التحديث: | 20231217 |
مُعرف محوري في PubMed: | PMC10708266 |
DOI: | 10.3390/nu15234871 |
PMID: | 38068730 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2072-6643 |
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DOI: | 10.3390/nu15234871 |