دورية أكاديمية
أعرض في EDS

Altered cortical thickness of the superior frontal gyrus and fusiform gyrus in individuals with subthreshold social anxiety.

التفاصيل البيبلوغرافية
العنوان: Altered cortical thickness of the superior frontal gyrus and fusiform gyrus in individuals with subthreshold social anxiety.
المؤلفون: Kim BH; Department of Psychiatry, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-Ro, Bundang-Gu, Seongnam-Si, Gyeonggi-Do, 463-712, Republic of Korea., Park SY; CHA University School of Medicine, Seongnam, Republic of Korea., Park CI; Department of Psychiatry, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-Ro, Bundang-Gu, Seongnam-Si, Gyeonggi-Do, 463-712, Republic of Korea., Bang M; Department of Psychiatry, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-Ro, Bundang-Gu, Seongnam-Si, Gyeonggi-Do, 463-712, Republic of Korea., Kim HJ; Department of Psychiatry, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-Ro, Bundang-Gu, Seongnam-Si, Gyeonggi-Do, 463-712, Republic of Korea. hyunju3141@chamc.co.kr., Lee SH; Department of Psychiatry, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-Ro, Bundang-Gu, Seongnam-Si, Gyeonggi-Do, 463-712, Republic of Korea. drshlee@cha.ac.kr.; CHA University School of Medicine, Seongnam, Republic of Korea. drshlee@cha.ac.kr.
المصدر: Scientific reports [Sci Rep] 2023 Dec 09; Vol. 13 (1), pp. 21822. Date of Electronic Publication: 2023 Dec 09.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Brain* , Performance Anxiety*, Humans ; Temporal Lobe ; Fear ; Prefrontal Cortex ; Magnetic Resonance Imaging
مستخلص: Subthreshold social anxiety (SSA) is a condition in which individuals experience social anxiety that does not reach the threshold required for a clinical diagnosis of a social anxiety disorder (SAD). Although SSA may not impair lives as severely as SAD, it can affect social functioning. However, only a few studies focused on structural neural correlates of SSA. We recruited 65 individuals with SSA and used the Leibowitz Social Anxiety Scale to assess their social and performance anxiety levels and other relevant measures of social anxiety. Voxel-wise whole-brain correlational analyses showed a positive association between the cortical thickness (CT) of the superior frontal gyrus (SFG) and social anxiety levels and a negative correlation between the CT of the fusiform gyrus (FG) and performance anxiety levels in individuals with SSA. Exploratory Pearson's correlation analyses showed significant positive correlations between the CT of the SFG and Generalized Anxiety Disorder-7 total scores and negative associations between the CT of the FG and Beck Anxiety Inventory total scores. Our study provides insight into the neural basis of SSA, particularly performance anxiety, by highlighting the association between CT in specific brain regions and SSA characteristics.
(© 2023. The Author(s).)
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معلومات مُعتمدة: HI23C0297000023 Ministry of Health & Welfare, Republic of Korea; NRF-2021R1C1C1012901 Ministry of Science and ICT, South Korea; NRF-2019M3C7A1032262 Ministry of Science and ICT, South Korea
تواريخ الأحداث: Date Created: 20231209 Date Completed: 20231216 Latest Revision: 20231226
رمز التحديث: 20231227
مُعرف محوري في PubMed: PMC10710474
DOI: 10.1038/s41598-023-49288-7
PMID: 38071248
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-023-49288-7