دورية أكاديمية
Current Applications of Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) in Pharmaceutical Analysis: Review.
| العنوان: | Current Applications of Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) in Pharmaceutical Analysis: Review. |
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| المؤلفون: | Alaoui Mansouri M; Nano and Molecular Systems Research Unit, University of Oulu, FI-90014 Oulu, Finland; University of Liege (ULiege), CIRM, Vibra-Santé HUB, Laboratory of Pharmaceutical Analytical Chemistry, CHU, B36, B-4000, Liege, Belgium. Electronic address: mohammed.alaouimansouri@oulu.fi., Kharbach M; Research Unit of Mathematical Sciences, University of Oulu, FI-90014 Oulu, Finland. Electronic address: mourad1kharbach@gmail.com., Bouklouze A; Bio-Pharmaceutical and Toxicological Analysis Research Team, Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco. |
| المصدر: | Journal of pharmaceutical sciences [J Pharm Sci] 2024 Apr; Vol. 113 (4), pp. 856-865. Date of Electronic Publication: 2023 Dec 08. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : New York, NY : Elsevier Original Publication: Easton, Pa., American Pharmaceutical Assn. |
| مواضيع طبية MeSH: | Biopharmaceutics*, Least-Squares Analysis ; Pharmaceutical Preparations ; Multivariate Analysis |
| مستخلص: | The present review encompasses various applications of multivariate curve resolution- alternating least squares (MCR-ALS) as a promising data handling, which is issued by analytical techniques in pharmaceutics. It involves different sections starting from a concise theory of MCR-ALS and four detailed applications in drugs analysis. Dissolution, stability, polymorphism, and quantification are the main four detailed applications. The data generated by analytical techniques associated with MCR-ALS deals accurately with different challenges compared to other chemometric tools. For each reviewed purpose, it was explained how MCR-ALS was applied and detailed information was given. Different approaches were introduced to overcome challenges that limit the use of MCR-ALS efficiently in pharmaceutical mixture were also discussed. Competing Interests: Declaration of Competing Interest The authors declare that there is no conflict of interest. (Copyright © 2023 American Pharmacists Association. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Dissolution; Drug stability; MCR-ALS; Pharmaceutical analysis; Photodegradation; Polymorphism; Quantitation |
| المشرفين على المادة: | 0 (Pharmaceutical Preparations) |
| تواريخ الأحداث: | Date Created: 20231210 Date Completed: 20240319 Latest Revision: 20240807 |
| رمز التحديث: | 20240807 |
| DOI: | 10.1016/j.xphs.2023.12.004 |
| PMID: | 38072117 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1520-6017 |
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| DOI: | 10.1016/j.xphs.2023.12.004 |