دورية أكاديمية
Thrombosis density ratio can predict the occurrence of pulmonary embolism and post-thrombotic syndrome in lower-extremity deep vein thrombosis patients.
| العنوان: | Thrombosis density ratio can predict the occurrence of pulmonary embolism and post-thrombotic syndrome in lower-extremity deep vein thrombosis patients. |
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| المؤلفون: | Yao MM; Imaging Teaching and Research Office, School of Medicine, Quanzhou Medical College, Quanzhou, Fujian, China., Lin TT; Training Teaching and Research Section, School of Medicine, Quanzhou Medical College, Quanzhou, Fujian, China., Shi X; Imaging Teaching and Research Office, School of Medicine, Quanzhou Medical College, Quanzhou, Fujian, China., Chen MG; Department of Imaging, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China., Wu JX; Imaging Teaching and Research Office, School of Medicine, Quanzhou Medical College, Quanzhou, Fujian, China., Zhao YP; Imaging Teaching and Research Office, School of Medicine, Quanzhou Medical College, Quanzhou, Fujian, China., Lin BS; Department of Child Health, Quanzhou Women's and Children's Hospital, Quanzhou, Fujian, China. |
| المصدر: | Clinical hemorheology and microcirculation [Clin Hemorheol Microcirc] 2024; Vol. 86 (4), pp. 395-405. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Ios Press Country of Publication: Netherlands NLM ID: 9709206 Publication Model: Print Cited Medium: Internet ISSN: 1875-8622 (Electronic) Linking ISSN: 13860291 NLM ISO Abbreviation: Clin Hemorheol Microcirc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Ios Press Original Publication: Amsterdam ; Washington, DC : IOS Press, c1997- |
| مواضيع طبية MeSH: | Pulmonary Embolism*/diagnostic imaging , Venous Thrombosis*/diagnostic imaging , Venous Thrombosis*/complications , Postthrombotic Syndrome* , Lower Extremity*/blood supply, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Aged ; Adult |
| مستخلص: | Objective: Deep vein thrombosis (DVT) formation of lower extremities can lead to serious complications including pulmonary embolism (PE) and chronic post-thrombotic syndrome (PTS). We aimed to explore the relationship between the ratio of thrombotic density and the occurrence of PE and PTS in patients with DVT of the lower extremities. Methods: A retrospective analysis was conducted in patients who performed computed tomography venography, dividing into DVT with PE group (54 patients) and DVT-alone group (34 patients), The clinical data were recorded. Univariate and multivariate logistic regression analysis were used to analysis variables associated with PE. The ability of thrombosis density ratio and Wells score to diagnose PE was evaluated by using the receiver operating characteristic curve (ROC) area under the curve (AUC). According to the treatment and follow-up results, subgroup analysis was performed, and the Villata score was used to determine the presence or absence of PTS and its severity. Results: Compare with the DVT-alone group, more patients had dyspnea and chest pain in the DVT with PE group. DVT with PE group had lower the percentage of neutrophils, white blood cell count and platelet count, while had higher blood cell count, D-dimer, wells score, thrombus and thrombus density ratio. Multivariate logistic analysis showed that percentage of neutrophils (OR(95% CIs)=1.15 (1.01,1.31), P = 0.040), platelets (OR(95% CIs)=0.96 (0.93,0.99), P = 0.011), and thrombus density ratio (OR(95% CIs)=5.99 (1.96,18.35), P = 0.002) are independent predictors of PE. The Wells score and thrombosis density ratio were consistent in the diagnostic efficacy of PE. In the subgroup analysis, there was a relevance between the ratio of thrombosis density and the Villalta score. Conclusion: Percentage of neutrophils, platelets, and thrombus density ratio are independent predictors of PE. The thrombosis density of DVT patients may be an index to predict the risk of PE and PTS in DVT patients. |
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| فهرسة مساهمة: | Keywords: Deep vein thrombosis of lower limbs; post-thrombotic syndrome; pulmonary embolism; thrombotic density ratio |
| تواريخ الأحداث: | Date Created: 20231211 Date Completed: 20240510 Latest Revision: 20240516 |
| رمز التحديث: | 20240516 |
| مُعرف محوري في PubMed: | PMC11091615 |
| DOI: | 10.3233/CH-231778 |
| PMID: | 38073380 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1875-8622 |
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| DOI: | 10.3233/CH-231778 |