دورية أكاديمية

Preparation and biomedical applications of artificial cells.

التفاصيل البيبلوغرافية
العنوان: Preparation and biomedical applications of artificial cells.
المؤلفون: Xu Q; Department of Materials Physics and Chemistry, School of Materials Science and Engineering, Key Laboratory for Anisotropy and Texture of Materials, Ministry of Education, Northeastern University, Shenyang, Liaoning, 110819, China.; Institute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning, 110016, China., Zhang Z; Institute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning, 110016, China.; School of Materials Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China., Lui PPY; Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, 999077, Hong Kong., Lu L; Institute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning, 110016, China.; School of Materials Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China., Li X; Department of Materials Physics and Chemistry, School of Materials Science and Engineering, Key Laboratory for Anisotropy and Texture of Materials, Ministry of Education, Northeastern University, Shenyang, Liaoning, 110819, China., Zhang X; Institute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning, 110016, China.; School of Materials Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.
المصدر: Materials today. Bio [Mater Today Bio] 2023 Nov 24; Vol. 23, pp. 100877. Date of Electronic Publication: 2023 Nov 24 (Print Publication: 2023).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101757228 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-0064 (Electronic) Linking ISSN: 25900064 NLM ISO Abbreviation: Mater Today Bio Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [London] : Elsevier Ltd., [2019]-
مستخلص: Artificial cells have received much attention in recent years as cell mimics with typical biological functions that can be adapted for therapeutic and diagnostic applications, as well as having an unlimited supply. Although remarkable progress has been made to construct complex multifunctional artificial cells, there are still significant differences between artificial cells and natural cells. It is therefore important to understand the techniques and challenges for the fabrication of artificial cells and their applications for further technological advancement. The key concepts of top-down and bottom-up methods for preparing artificial cells are summarized, and the advantages and disadvantages of the bottom-up methods are compared and critically discussed in this review. Potential applications of artificial cells as drug carriers (microcapsules), as signaling regulators for coordinating cellular communication and as bioreactors for biomolecule fabrication, are further discussed. The challenges and future trends for the development of artificial cells simulating the real activities of natural cells are finally described.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2023 The Authors.)
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فهرسة مساهمة: Keywords: Artificial cells; Bioreactors; Bottom-up approach; Cellular communication; Microcapsules
تواريخ الأحداث: Date Created: 20231211 Latest Revision: 20231211
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10701372
DOI: 10.1016/j.mtbio.2023.100877
PMID: 38075249
قاعدة البيانات: MEDLINE
الوصف
تدمد:2590-0064
DOI:10.1016/j.mtbio.2023.100877