دورية أكاديمية
Plateauing atrial fibrillation burden in acute ischemic stroke admissions in the United States from 2010 to 2020.
| العنوان: | Plateauing atrial fibrillation burden in acute ischemic stroke admissions in the United States from 2010 to 2020. |
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| المؤلفون: | Otite FO; Department of Neurology, State University of New York Upstate Medical University, Syracuse, NY, USA., Patel SD; Department of Neurosurgery, University of Connecticut, Hartford, CT, USA., Aneni E; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA., Lamikanra O; Department of Critical Care, Springfield Clinic, Springfield, IL, USA., Wee C; Department of Neurology, State University of New York Upstate Medical University, Syracuse, NY, USA., Albright KC; Department of Neurology, State University of New York Upstate Medical University, Syracuse, NY, USA., Burke D; Department of Neurology, State University of New York Upstate Medical University, Syracuse, NY, USA., Latorre JG; Department of Neurology, State University of New York Upstate Medical University, Syracuse, NY, USA., Morris NA; Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA., Anikpezie N; Department of Population Health, University of Mississippi Medical Center, Jackson, MS, USA., Singla A; Department of Neurosurgery, Rutgers University, Newark, NJ, USA., Sonig A; Department of Neurosurgery, Rutgers University, Newark, NJ, USA., Kamel H; Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY, USA., Khandelwal P; Department of Neurosurgery, Rutgers University, Newark, NJ, USA., Chaturvedi S; Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA. |
| المصدر: | International journal of stroke : official journal of the International Stroke Society [Int J Stroke] 2024 Jun; Vol. 19 (5), pp. 547-558. Date of Electronic Publication: 2024 Jan 02. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 101274068 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4949 (Electronic) Linking ISSN: 17474930 NLM ISO Abbreviation: Int J Stroke Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : Thousand Oaks, CA : SAGE Publications Original Publication: Oxford, UK : Blackwell Pub., c2005- |
| مواضيع طبية MeSH: | Atrial Fibrillation*/epidemiology , Atrial Fibrillation*/complications , Ischemic Stroke*/epidemiology , Hospitalization*/statistics & numerical data , Hospitalization*/trends, Humans ; Male ; Female ; United States/epidemiology ; Middle Aged ; Aged ; Cross-Sectional Studies ; Prevalence ; Aged, 80 and over ; Adult ; Young Adult ; Adolescent |
| مستخلص: | Background: Utilization of oral anticoagulants for acute ischemic stroke (AIS) prevention in patients with atrial fibrillation (AF) increased in the United States over the last decade. Whether this increase has been accompanied by any change in AF prevalence in AIS at the population level remains unknown. The aim of this study is to evaluate trends in AF prevalence in AIS hospitalizations in various age, sex, and racial subgroups over the last decade. Methods: We used data contained in the 2010-2020 National Inpatient Sample to conduct a serial cross-sectional study. Primary AIS hospitalizations with and without comorbid AF were identified using International Classification of Diseases Codes. Joinpoint regression was used to compute annualized percentage change (APC) in prevalence and to identify points of change in prevalence over time. Results: Of 5,190,148 weighted primary AIS hospitalizations over the study period, 25.1% had comorbid AF. The age- and sex-standardized prevalence of AF in AIS hospitalizations increased across the entire study period 2010-2020 (average APC: 1.3%, 95% confidence interval (CI): 0.8-1.7%). Joinpoint regression showed that prevalence increased in the period 2010-2015 (APC: 2.8%, 95% CI: 1.9-3.9%) but remained stable in the period 2015-2020 (APC: -0.3%, 95% CI: -1.0 to 1.9%). Upon stratification by age and sex, prevalence increased in all age/sex groups from 2010 to 2015 and continued to increase throughout the entire study period in hospitalizations in men 18-39 years (APC: 4.0%, 95% CI: 0.2-7.9%), men 40-59 years (APC: 3.4%, 95% CI: 1.9-4.9%) and women 40-59 years (APC: 4.4%, 95% CI: 2.0-6.8%). In contrast, prevalence declined in hospitalizations in women 60-79 (APC: -1.0%, 95% CI: -0.5 to -1.5%) and women ⩾ 80 years over the period 2015-2020 but plateaued in hospitalizations in similar-aged men over the same period. Conclusion: AF prevalence in AIS hospitalizations in the United States increased over the period 2010-2015, then plateaued over the period 2015-2020 due to declining prevalence in hospitalizations in women ⩾ 60 years and plateauing prevalence in hospitalizations in men ⩾ 60 years. Competing Interests: Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Dr Kamel is an associate editor for JAMA neurology; and the principal investigator of the ARCADIA trial, testing antithrombotic strategies in patients with stroke and atrial cardiopathy; and of the ASPIRE trial, which is testing antithrombotic strategies in patients with atrial fibrillation and intracerebral hemorrhage. Dr Chaturvedi is an associate editor for the Stroke journal. |
| فهرسة مساهمة: | Keywords: Stroke subtypes; cardio-aortic embolism; epidemiology; ischemic stroke; prevention; risk factors |
| تواريخ الأحداث: | Date Created: 20231212 Date Completed: 20240528 Latest Revision: 20240528 |
| رمز التحديث: | 20240528 |
| DOI: | 10.1177/17474930231222163 |
| PMID: | 38086764 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1747-4949 |
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| DOI: | 10.1177/17474930231222163 |