دورية أكاديمية
Ethnic Differences in Carotid Intima Media Thickness and Plaque Presence - The HELIUS study.
| العنوان: | Ethnic Differences in Carotid Intima Media Thickness and Plaque Presence - The HELIUS study. |
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| المؤلفون: | Vriend EMC, Bouwmeester TA, Artola Arita VA, Bots ML, Meijer R, Galenkamp H, Stronks K, Collard D, Moll van Charante EP, van den Born BH, Franco OH |
| المصدر: | Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2023 Dec 13. Date of Electronic Publication: 2023 Dec 13. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Karger Country of Publication: Switzerland NLM ID: 9100851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9786 (Electronic) Linking ISSN: 10159770 NLM ISO Abbreviation: Cerebrovasc Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel ; New York : Karger, 1990- |
| مستخلص: | Introduction In the Netherlands, the prevalence of cardiovascular diseases (CVD) is higher among South-Asian Surinamese and lower among Moroccans compared to the Dutch. Traditional risk factors for atherosclerotic CVD do not fully explain these disparities. We aim to assess ethnic differences in plaque presence and intima media thickness (cIMT) and explore to which extent these differences are explained by traditional risk factors. Methods We used cross-sectional data from a subgroup of participants enrolled in the multi-ethnic population-based HEalthy Life In an Urban Setting (HELIUS) study who underwent carotid ultrasonography. Logistic and linear regression models were built to assess ethnic differences in plaque presence and cIMT with the Dutch population as reference. Additional models were created to adjust for socioeconomic status, body height and cardiovascular risk factors. Results Of the 3022 participants, 1183, 1051 and 790 individuals were of Dutch, South-Asian Surinamese and Moroccan descent. Mean age was 60.9 years (SD 8.0), 52.8% was female. Compared to the Dutch, we found lower odds for plaque presence in Moroccans (0.77, 95% CI 0.62; 0.95) and no significant differences between the South-Asian Surinamese and Dutch population (0.91, 95% CI 0.76; 1.10). After adjustment for CVD risk factors, we found a lower plaque presence in South-Asian Surinamese (0.63, 95% CI 0.48; 0.82). In both Moroccan and South-Asian Surinamese individuals, adjustment for socioeconomic status did not materially change the results. cIMT was lower in South-Asian Surinamese compared to the Dutch (-17.9 µm, 95% CI -27.9; -7.9) and partly explained by ethnic differences in body height as South-Asian Surinamese individuals were, on average, shorter than the Dutch population. No differences in cIMT between Moroccans and Dutch were found. Conclusions cIMT and plaque prevalence differ between ethnic groups independent of CVD risk. Lower plaque prevalence in Moroccans was partly attributable to a lower prevalence of traditional CVD risk factors, while body height was an important contributor to differences in cIMT in South-Asians. This study emphasizes the need for ethnic-specific cut-off values for plaque presence and cIMT. (The Author(s). Published by S. Karger AG, Basel.) |
| تواريخ الأحداث: | Date Created: 20231213 Latest Revision: 20231213 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1159/000535713 |
| PMID: | 38091958 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1421-9786 |
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| DOI: | 10.1159/000535713 |