دورية أكاديمية

Pharmacologic Management of Obesity after Liver Transplantation: A Critical Review.

التفاصيل البيبلوغرافية
العنوان: Pharmacologic Management of Obesity after Liver Transplantation: A Critical Review.
المؤلفون: Zahrawi F; Section of Digestive Diseases, Yale School of Medicine, PO Box 208019, New Haven, CT 06520, USA., Fathma S; Waterbury Hospital, Yale New Haven Health, 64 Robbins St, Waterbury, CT 06708, USA., Mehal WZ; Section of Digestive Diseases, Yale School of Medicine, PO Box 208019, New Haven, CT 06520, USA., Banini BA; Section of Digestive Diseases, Yale School of Medicine, PO Box 208019, New Haven, CT 06520, USA.
المصدر: Annals of gastroenterology and digestive disorders [Ann Gastroenterol Dig Disord] 2023; Vol. 6 (1), pp. 17-25. Date of Electronic Publication: 2023 Jun 07.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Somato Publications Country of Publication: United States NLM ID: 101744923 Publication Model: Print-Electronic Cited Medium: Internet NLM ISO Abbreviation: Ann Gastroenterol Dig Disord Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Middle town, Delaware : Somato Publications
مستخلص: Post liver transplant obesity is associated with the development of metabolic disorders such as diabetes mellitus and nonalcoholic fatty liver disease and is a strong predictor of post-transplant mortality. Anti-obesity pharmacotherapy could serve as an effective adjunct to lifestyle modification in the post-transplant setting. Currently, utilization of anti-obesity medication in post liver transplant patients is limited by scarce data on their efficacy and safety in the post-transplant setting. Newer classes of anti-obesity medications, including the glucagon-like peptide 1 agonists (GLP-1) do not only help with weight loss but are effective anti-diabetic agents and are in further development for their potential hepatoprotective and renoprotective effects and reduction in cardiovascular risk. The objective of this manuscript was to critically review the efficacy and safety of anti-obesity pharmacotherapy in post-liver transplant patients.
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معلومات مُعتمدة: U54 AA027989 United States AA NIAAA NIH HHS
فهرسة مساهمة: Keywords: Anti-obesity medication; GLP-1 agonists; Liver transplant; Obesity; Solid organ transplant; Weight loss
تواريخ الأحداث: Date Created: 20231215 Latest Revision: 20231216
رمز التحديث: 20231216
مُعرف محوري في PubMed: PMC10719957
PMID: 38098758
قاعدة البيانات: MEDLINE