دورية أكاديمية
Primary malignant melanoma, an atypical presentation in the cervical spine: a case report.
| العنوان: | Primary malignant melanoma, an atypical presentation in the cervical spine: a case report. |
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| المؤلفون: | Kamabu LK; Department of Surgery, Neurosurgery, College of Medicine, Makerere University, Kampala, Uganda. kamabularry@gmail.com.; Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of the Congo. kamabularry@gmail.com., Kataka LM; Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of the Congo., Vivalya BMN; Department of Internal Medicine, Masereka General Hospital, Goma, North-Kivu, Democratic Republic of the Congo.; Department of Psychiatry and Mental Health, Kampala International University Western Campus, Ishaka, Uganda., Sikakulya FK; Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of the Congo.; Department of Surgery, Kampala International University, Western Campus, Ishaka, Uganda., Lekuya HM; Department of Surgery, Neurosurgery, College of Medicine, Makerere University, Kampala, Uganda.; Directorate of Surgical Services, Neurosurgical Unit, Mulago National Referral Hospital, Kampala, Uganda., Galukande M; Department of Surgery, Neurosurgery, College of Medicine, Makerere University, Kampala, Uganda. |
| المصدر: | Journal of medical case reports [J Med Case Rep] 2023 Dec 17; Vol. 17 (1), pp. 548. Date of Electronic Publication: 2023 Dec 17. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [London] : BioMed Central, [2007- |
| مواضيع طبية MeSH: | Melanoma*/diagnosis , Melanoma*/surgery , Melanoma*/pathology, Humans ; Male ; Middle Aged ; Radiography ; Magnetic Resonance Imaging ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery ; Neck/pathology |
| مستخلص: | Background: Few studies have documented the occurrence of melanoma in the cervical spine. Of all malignant melanoma cases, 1% are primary melanoma of the central nervous system, which makes it extremely uncommon and nonspecific. We aim to report a case of the uncommon presentation of primary melanoma in the cervical spine. Case Presentation: The patient was a 59-year-old Muganda male who presented with a 2-year history of anterior neck swelling as well as severe pain and a tingling sensation in the left shoulder and arm, which worsened in the recent 6 months. He developed weakness and paresthesia in the upper left arm and progressive gait disturbance of the left leg. A physical examination revealed masses in the left cervical and right submandibular region. Additionally, the upper and lower left extremities revealed hemiparesis and hemihypoesthesia. A magnetic resonance imaging scan showed a hyperintense lesion on TIWI and another hypointense lesion on T2WI, originating from the cervical spine and involving the vertebral bodies and paravertebral soft tissues. The patient underwent surgery, a black tumor was extracted, and histology revealed the tumor to be malignant melanoma. The patient died within 1 month after the diagnosis and surgery. Conclusion: This case is presented to highlight the significance and challenges associated with making a pre- and postoperative diagnosis of primary cervical melanoma with atypical radiological characteristics. Patients with extradural lesions that show hyperintensity on T1-weighted images and hypointensity on T2-weighted images should have spinal melanoma examined as a possible differential diagnosis. (© 2023. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Cervical spine; MRI; Malignant melanoma |
| تواريخ الأحداث: | Date Created: 20231216 Date Completed: 20231219 Latest Revision: 20231219 |
| رمز التحديث: | 20231219 |
| مُعرف محوري في PubMed: | PMC10725590 |
| DOI: | 10.1186/s13256-023-04290-5 |
| PMID: | 38104134 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1752-1947 |
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| DOI: | 10.1186/s13256-023-04290-5 |