دورية أكاديمية
أعرض في EDS

Phenolic constituents with antibacterial activity from Eleutherine bulbosa.

التفاصيل البيبلوغرافية
العنوان: Phenolic constituents with antibacterial activity from Eleutherine bulbosa.
المؤلفون: Sun Z; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China., Li Q; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China., Zhang J; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China., Sun Z; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China., Wu H; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China., Liang H; Department of Biomedicine, Beijing City University, Beijing 100094, China., Ma M; Key Laboratory of Resource Chemistry and Eco-environmental Protection in Qinghai-Tibet Plateau, Qinghai Minzu University, Xining 810007, China., Huang L; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China., Xu X; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. Electronic address: xdxu@implad.ac.cn., Ma G; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. Electronic address: mgxfl8785@163.com.
المصدر: Fitoterapia [Fitoterapia] 2024 Jan; Vol. 172, pp. 105787. Date of Electronic Publication: 2023 Dec 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : [Amsterdam] : Elsevier
Original Publication: Milano : Inverni & Della Beffa S.p.A.
مواضيع طبية MeSH: Anti-Bacterial Agents* , Iridaceae*, Animals ; Humans ; Molecular Structure ; Staphylococcus aureus ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Microbial Sensitivity Tests ; Phenols/pharmacology ; Phenols/chemistry ; Escherichia coli
مستخلص: Eleutherine bulbosa (Mill.) Urb. is a medicinal and edible plant with various benefits for humans and animals. In this work, four new phenolic constituents (1-4), along with six known phenolic compounds (5-10) were obtained from the red bulbs of E. bulbosa. Their structures with absolute configurations were characterized by extensive spectroscopic analysis, combined with HR-ESI-MS and quantum mechanical electronic circular dichroism (ECD). Compounds 1 and 2 are novel homologous and heterodimers, respectively, featuring an unusual spiro ring system. All isolated phenolic constituents were tested for their antibacterial effects. The results revealed four phenolic compounds 1-3 and 7 showed moderate antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Escherichia coli with minimum inhibitory concentration (MIC) values ranging from 15.6 to 250.0 μg/mL.
Competing Interests: Declaration of Competing Interest The authors declare no conflicts of interest.
(Copyright © 2023. Published by Elsevier B.V.)
فهرسة مساهمة: Keywords: Antibacterial activity; Dimers; Eleutherine bulbosa; Phenolic constituents
المشرفين على المادة: 0 (Anti-Bacterial Agents)
0 (Plant Extracts)
0 (Phenols)
تواريخ الأحداث: Date Created: 20231220 Date Completed: 20240112 Latest Revision: 20240112
رمز التحديث: 20240112
DOI: 10.1016/j.fitote.2023.105787
PMID: 38122855
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-6971
DOI:10.1016/j.fitote.2023.105787