دورية أكاديمية

Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.

التفاصيل البيبلوغرافية
العنوان: Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
المؤلفون: Jana J; Institut für Biochemie, Universität Greifswald, Felix-Hausdorff Str. 4, Greifswald D-17489, Germany. weisz@uni-greifswald.de., Vianney YM; Institut für Biochemie, Universität Greifswald, Felix-Hausdorff Str. 4, Greifswald D-17489, Germany. weisz@uni-greifswald.de., Weisz K; Institut für Biochemie, Universität Greifswald, Felix-Hausdorff Str. 4, Greifswald D-17489, Germany. weisz@uni-greifswald.de.
المصدر: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Jan 18; Vol. 60 (7), pp. 854-857. Date of Electronic Publication: 2024 Jan 18.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: PubMed not MEDLINE; MEDLINE
أسماء مطبوعة: Original Publication: Cambridge : Royal Society of Chemistry
مستخلص: A G-rich core sequence G 3 -TCA-G 3 -T 1,2 -G 3 -T 1,2 -G 3 can be designed to fold into a parallel or into two different (3+1) hybrid-type G-quadruplexes, among them an elusive topology with one lateral followed by two propeller loops. Favored folds can be rationalized based on the number of intervening thymidines and on additional complementary flanking sequences.
تواريخ الأحداث: Date Created: 20231222 Latest Revision: 20240118
رمز التحديث: 20240118
DOI: 10.1039/d3cc05625b
PMID: 38131370
قاعدة البيانات: MEDLINE
الوصف
تدمد:1364-548X
DOI:10.1039/d3cc05625b