دورية أكاديمية
أعرض في EDS

Hydrolysis of Oligodeoxyribonucleotides on the Microarray Surface and in Solution by Catalytic Anti-DNA Antibodies in Systemic Lupus Erythematosus.

التفاصيل البيبلوغرافية
العنوان: Hydrolysis of Oligodeoxyribonucleotides on the Microarray Surface and in Solution by Catalytic Anti-DNA Antibodies in Systemic Lupus Erythematosus.
المؤلفون: Novikova TS; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia., Ermakov EA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia., Kostina EV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Sinyakov AN; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Sizikov AE; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Institute of Clinical Immunology, Siberian Branch of the Russian Academy of Sciences, 630099 Novosibirsk, Russia., Nevinsky GA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia., Buneva VN; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
المصدر: Current issues in molecular biology [Curr Issues Mol Biol] 2023 Dec 08; Vol. 45 (12), pp. 9887-9903. Date of Electronic Publication: 2023 Dec 08.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100931761 Publication Model: Electronic Cited Medium: Internet ISSN: 1467-3045 (Electronic) Linking ISSN: 14673037 NLM ISO Abbreviation: Curr Issues Mol Biol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2021- : Basel, Switzerland : MDPI
Original Publication: Wymondham, Norfolk, UK : Caister Academic Press,
مستخلص: Anti-DNA antibodies are known to be classical serological hallmarks of systemic lupus erythematosus (SLE). In addition to high-affinity antibodies, the autoantibody pool also contains natural catalytic anti-DNA antibodies that recognize and hydrolyze DNA. However, the specificity of such antibodies is uncertain. In addition, DNA binding to a surface such as the cell membrane, can also affect its recognition by antibodies. Here, we analyzed the hydrolysis of short oligodeoxyribonucleotides (ODNs) immobilized on the microarray surface and in solution by catalytic anti-DNA antibodies from SLE patients. It has been shown that IgG antibodies from SLE patients hydrolyze ODNs more effectively both in solution and on the surface, compared to IgG from healthy individuals. The data obtained indicate a more efficient hydrolysis of ODNs in solution than immobilized ODNs on the surface. In addition, differences in the specificity of recognition and hydrolysis of certain ODNs by anti-DNA antibodies were revealed, indicating the formation of autoantibodies to specific DNA motifs in SLE. The data obtained expand our understanding of the role of anti-DNA antibodies in SLE. Differences in the recognition and hydrolysis of surface-tethered and dissolved ODNs need to be considered in DNA microarray applications.
References: J Am Chem Soc. 2002 Sep 18;124(37):10988-9. (PMID: 12224940)
J Immunol. 2013 Nov 15;191(10):4926-39. (PMID: 24108696)
Biomed Pharmacother. 2003 Sep;57(7):278-81. (PMID: 14499173)
Scand J Immunol. 2001 Jul-Aug;54(1-2):211-9. (PMID: 11439169)
Immunol Lett. 2000 Jul 3;73(1):29-34. (PMID: 10963808)
Clin Immunol. 2001 Aug;100(2):157-63. (PMID: 11465944)
Langmuir. 2005 Apr 26;21(9):4050-7. (PMID: 15835973)
J Mol Recognit. 2016 Dec;29(12):596-610. (PMID: 27558754)
Curr Opin Biotechnol. 2005 Aug;16(4):385-92. (PMID: 16005203)
Nat Rev Nephrol. 2016 Jul;12(7):402-13. (PMID: 27241241)
Nat Rev Rheumatol. 2020 Oct;16(10):565-579. (PMID: 32884126)
Nat Rev Rheumatol. 2016 Feb;12(2):102-10. (PMID: 26581343)
RMD Open. 2018 Nov 27;4(2):e000793. (PMID: 30564454)
Autoimmun Rev. 2006 May;5(5):324-30. (PMID: 16782557)
Arthritis Rheumatol. 2014 May;66(5):1061-9. (PMID: 24470458)
IUBMB Life. 2018 Feb;70(2):153-164. (PMID: 29341394)
J Mol Biol. 1994 Feb 18;236(2):405-11. (PMID: 8107130)
Clin Immunol. 2021 Oct;231:108848. (PMID: 34492381)
Arthritis Res Ther. 2017 May 2;19(1):85. (PMID: 28464939)
J Mol Biol. 2001 Dec 7;314(4):807-22. (PMID: 11733999)
Arthritis Rheum. 2001 Oct;44(10):2342-9. (PMID: 11665975)
Arthritis Rheum. 2006 Nov;54(11):3623-32. (PMID: 17075807)
Clin Immunol. 2017 Dec;185:40-50. (PMID: 27612436)
Front Immunol. 2019 Jul 17;10:1667. (PMID: 31379858)
Int J Mol Sci. 2020 Jul 29;21(15):. (PMID: 32751323)
Mol Immunol. 1983 Jun;20(6):581-8. (PMID: 6192329)
Appl Biochem Biotechnol. 2023 Feb;195(2):1514-1540. (PMID: 36222989)
J Inflamm Res. 2020 Oct 08;13:681-699. (PMID: 33116748)
Org Lett. 2003 Apr 17;5(8):1257-60. (PMID: 12688733)
Clin Rev Allergy Immunol. 2020 Apr;58(2):213-228. (PMID: 31161341)
N Engl J Med. 2005 Dec 15;353(24):2550-8. (PMID: 16354891)
J Immunol Methods. 1987 Jul 16;101(1):63-71. (PMID: 3611793)
Front Immunol. 2019 Mar 19;10:502. (PMID: 30941136)
Eur J Clin Invest. 2018 Nov;48(11):e13015. (PMID: 30079480)
Int J Mol Sci. 2022 May 07;23(9):. (PMID: 35563617)
Clin Immunol. 2023 Oct;255:109763. (PMID: 37673226)
J Immunol. 2015 Jan 1;194(1):13-20. (PMID: 25527792)
Biochemistry. 1996 Feb 6;35(5):1624-33. (PMID: 8634294)
Nat Rev Dis Primers. 2016 Jun 16;2:16039. (PMID: 27306639)
J Cell Mol Med. 2003 Jul-Sep;7(3):265-76. (PMID: 14594551)
Arthritis Rheumatol. 2017 Mar;69(3):487-493. (PMID: 27899010)
J Am Chem Soc. 2002 Dec 18;124(50):14868-70. (PMID: 12475327)
IUBMB Life. 2019 Sep;71(9):1201-1210. (PMID: 31091350)
J Immunol Methods. 1988 Nov 25;115(1):71-8. (PMID: 2461416)
Trends Biotechnol. 2008 Jun;26(6):328-37. (PMID: 18430479)
Int J Nephrol Renovasc Dis. 2011;4:17-28. (PMID: 21694945)
Nat Rev Rheumatol. 2015 Sep;11(9):530-40. (PMID: 26034836)
Int J Mol Sci. 2022 Nov 08;23(22):. (PMID: 36430159)
Bioorg Khim. 2015 Jan-Feb;41(1):124-8. (PMID: 26050481)
Anal Chem. 2005 Oct 15;77(20):6528-34. (PMID: 16223236)
Rheumatology (Oxford). 2023 May 19;:. (PMID: 37208196)
J Autoimmun. 2011 Sep;37(2):144-50. (PMID: 21624820)
Clin Exp Immunol. 2021 Jan;203(1):32-40. (PMID: 32959462)
Endocr Metab Immune Disord Drug Targets. 2022;22(8):852-861. (PMID: 35249511)
Clin Immunol. 2006 Feb-Mar;118(2-3):209-18. (PMID: 16298553)
J Mol Recognit. 2013 Oct;26(10):450-60. (PMID: 23996487)
Eur J Rheumatol. 2018 Sep;5(3):173-178. (PMID: 30185370)
Ann Rheum Dis. 2019 Sep;78(9):1151-1159. (PMID: 31383717)
Mol Biol (Mosk). 2021 Jul-Aug;55(4):562-577. (PMID: 34432774)
Am J Hum Genet. 2020 Feb 6;106(2):202-214. (PMID: 32004449)
Langmuir. 2012 Oct 16;28(41):14665-71. (PMID: 22978617)
Anal Chem. 2004 May 1;76(9):2664-8. (PMID: 15117213)
Nat Rev Rheumatol. 2016 Nov 22;12(12):716-730. (PMID: 27872476)
Science. 1992 May 1;256(5057):665-7. (PMID: 1585181)
معلومات مُعتمدة: 23-15-00357 Russian Science Foundation; 121031300042-1 Russian state-funded project for ICBFM SB RAS; 121031300041-4 Russian state-funded project for ICBFM SB RAS
فهرسة مساهمة: Keywords: DNase I; SLE; abzymes; anti-DNA antibodies; antinuclear antibodies; microarray; natural catalytic antibodies; recognition; sequence specificity; systemic lupus erythematosus
تواريخ الأحداث: Date Created: 20231222 Latest Revision: 20231224
رمز التحديث: 20231224
مُعرف محوري في PubMed: PMC10742339
DOI: 10.3390/cimb45120617
PMID: 38132463
قاعدة البيانات: MEDLINE
الوصف
تدمد:1467-3045
DOI:10.3390/cimb45120617